Cost-effectiveness of ventricular assist device therapy as a bridge to transplantation compared with nonbridged cardiac recipients

Circulation

Volumn 127, Issue 24, 2013, Pages 2424-2435

  Alba, Ana C ^a   Alba, Luis F ^a,b   Delgado, Diego H ^a   Rao, Vivek ^a   Ross, Heather J ^a   Goeree, Ron ^c  

^a TORONTO GENERAL HOSPITAL   (Canada)

^b UNIVERSIDAD NACIONAL DE CUYO   (Argentina)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Cost benefit analysis; Economics; Heart failure; Heart transplantation; Heart assist devices

Indexed keywords

ARTICLE; ASSISTED CIRCULATION; CARDIAC ALLOGRAFT VASCULOPATHY; CLINICAL DECISION MAKING; COST EFFECTIVENESS ANALYSIS; ECONOMIC EVALUATION; HEALTH CARE COST; HEART FAILURE; HEART GRAFT; HEART TRANSPLANTATION; HIGH RISK PATIENT; HOSPITAL ADMISSION; HUMAN; INFECTION COMPLICATION; INTRAAORTIC BALLOON PUMP; KIDNEY DYSFUNCTION; KIDNEY FAILURE; LOW RISK POPULATION; META ANALYSIS; PRIORITY JOURNAL; SURVIVAL; SURVIVAL TIME; SYSTEMATIC REVIEW; THROMBOEMBOLISM; VENTRICULAR ASSIST DEVICE;

COST-BENEFIT ANALYSIS; ECONOMICS; HEART FAILURE; HEART TRANSPLANTATION; HEART-ASSIST DEVICES;

ADULT; COST-BENEFIT ANALYSIS; DECISION SUPPORT TECHNIQUES; FEMALE; HEALTH CARE COSTS; HEART FAILURE; HEART TRANSPLANTATION; HEART-ASSIST DEVICES; HUMANS; MALE; MARKOV CHAINS; MIDDLE AGED; MODELS, STATISTICAL; SURVIVAL RATE; TRANSPLANTATION; TREATMENT OUTCOME;

EID: 84879295237     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.000194     Document Type: Article

References (36)

1. Dracup K, Walden JA, Stevenson L.W., Brecht M. Quality of life with advanced heart failure. J Heart Lung Transplant. 1992;11:273-279.
2. Murray SA, Boyd K, Kendall M., Worth A, Benton TF, Clausen H. Dying of lung cancer or cardiac failure: prospective qualitative interview study of patients and their carers in the community. BMJ. 2002;325:929.
3. Chow CM, Donovan L, Manuel D., Johasen H, Tu JV Regional variation in self-reported Herat disease prevalence in Canada. Can J Cardiol. 2005;21, 1265-1271.
4. Goodlin SJ, Hauptman PJ, Arnold R, Grady K., Hershberger RE, Kutner J, Masoudi F, Spertus J., Dracup K, Cleary JF, Medak R, Crispell K., Piña I, Stuart B., Whitney C, Rector T, Teno J., Renlund DG Consensus statement: palliative and supportive care in advanced heart failure. J Card Fail. 2004;10:200-209.
5. Hunt SA, Abraham WT, Chin M.H., Feldman AM, Francis GS, Ganiats TG, Jessup M, Konstam M.A., Mancini DM, Michl K, Oates JA, Rahko P.S., Silver MA, Stevenson LW, Yancy CW, Antman E.M., Smith SC Jr, Adams CD, Anderson JL, Faxon D P, Fuster V, Halperin J.L., Hiratzka LF, Jacobs AK, Nishimura R, Ornato J.P., Page RL, Riegel B; American College of Cardiology; American Heart Association Task Force on Practice Guidelines; American College of Chest Physicians; International Society for Heart and Lung Transplantation; Heart Rhythm Society. ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005;112:e154-e235.
6. Ho KK, Pinsky JL, Kannel W.B., Levy D. The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol. 1993;22(suppl A):6A-13A.
7. Rose EA, Gelijns AC, Moskowitz A.J., Heitjan DF, Stevenson LW, Dembitsky W, Long J.W., Ascheim DD, Tiernay AR, Levitan RG, Watson J.T., Meier P; Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group. Long-term mechanical left ventricular assistance for end-stage heart failure. N Engl J Med. 2001;345:1435-1443.
8. Kittleson M, Hurwitz S, Shah M.R., Nohria A., Lewis E, Givertz M, Fang J., Jarcho J, Mudge G, Stevenson LW Development of circulatory-renal limitations to angiotensin-converting enzyme inhibitors identifies patients with severe heart failure and early mortality. J Am Coll Cardiol. 2003;41:2029-2035.
9. Stehlik J, Edwards LB, Kucheryavaya A.Y., Aurora P., Christie JD, Kirk R, Dobbels F, Rahmel A.O., Hertz MI The Registry of the International Society for Heart and Lung Transplantation: twenty-seventh official adult heart transplant report-2010. J Heart Lung Transplant. 2010;29:1089-1103.
10. Lietz K, Miller LW Improved survival of patients with end-stage heart failure listed for heart transplantation: analysis of organ procurement and transplantation network/U.S. United Network of Organ Sharing data, 1990 to 2005. J Am Coll Cardiol. 2007;50:1282-1290.
11. Alba AC, Delgado DH The future is here: ventricular assist devices for the failing heart. Expert Rev Cardiovasc Ther. 2009;7:1067-1077.
12. Kirklin JK, Naftel DC, Kormos R.L., Stevenson LW, Pagani FD, Miller MA, Ulisney K.L., Baldwin JT, Young JB Third INTERMACS annual report: the evolution of destination therapy in the United States. J Heart Lung Transplant. 2011;30:115-123.
13. Kirklin JK, Naftel DC, Kormos R.L., Stevenson LW, Pagani FD, Miller MA, Baldwin J.T., Young JB The Fourth INTERMACS annual report: 4,000 implants and counting. J Heart Lung Transplant. 2012;31:117-126.
14. Haddad M, Hendry PJ, Masters R.G., Mesana T, Haddad H, Davies RA, Mus-sivand TV, Struthers C, Keon WJ. Ventricular assist devices as a bridge to cardiac transplantation: the Ottawa experience. Artif Organs. 2004;28:136-141.
15. Joyce DL, Southard RE, Torre-Amione G, Noon G.P., Land GA, Loebe M. Impact of left ventricular assist device (LVAD)-mediated humoral sensitization on post-transplant outcomes. J Heart Lung Transplant. 2005;24:2054-2059.
16. Lavee J, Kormos RL, Duquesnoy R.J., Zerbe TR, Armitage JM, Vanek M, Hardesty R.L., Griffith BP Influence of panel-reactive antibody and lym-phocytotoxic cross-match on survival after heart transplantation. J Heart Lung Transplant. 1991;10:921-930.
17. Alba AC, McDonald M, Rao V., Ross HJ, Delgado DH The effect of ventricular assist devices on long-term post-transplant outcomes: a systematic review of observational studies. Eur J Heart Fail. 2011;13:785-795.
18. Organ Procurement and Transplantation Network (OPTN) and Scientific Registry of Transplant Recipients (SRTR). OPTN/SRTR 2010 Annual Data Report. Rockville, MD: Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation; 2012.
19. Warner-Stevenson L. The evolving role of mechanical circulatory support in advanced heart failure. In: Frazier OH, Kirklin JK, eds. ISHLTMonograph Series Volume I: Mechanical Circulatory Support. 2006:181-203.
20. Nativi JN, Drakos SG, Kucheryavaya A.Y., Edwards LB, Selzman CH, Taylor DO, Hertz M.I., Kfoury AG, Stehlik J. Changing outcomes in patients bridged to heart transplantation with continuous-versus pulsatile-flow ventricular assist devices: an analysis of the registry of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2011;30:854-861.
21. Shuhaiber JH, Hur K, Gibbons R. The influence of preoperative use of ventricular assist devices on survival after heart transplantation: propensity score matched analysis. BMJ. 2010;340:c392.
22. Singh TP, Almond CS, Taylor D.O., Graham DA Decline in heart transplant wait list mortality in the United States following broader regional sharing of donor hearts. Circ Heart Fail. 2012;5:249-258.
23. Arnaoutakis GJ, George TJ, Kilic A, Weiss E.S., Russell SD, Conte JV, Shah AS Effect of sensitization in US heart transplant recipients bridged with a ventricular assist device: update in a modern cohort. J Thorac Cardiovasc Surg. 2011;142:1236-45, 1245.e1.
24. Christie JD, Edwards LB, Kucheryavaya A.Y., Benden C., Dobbels F Kirk R. The Registry of the International Society for Heart and Lung Transplantation: Twenty-Eighth Adult Lung and Heart-Lung Transplant Report-2011. J Heart Lung Transplant. 2011;30:1104-1122.
25. Starling RC, Naka Y, Boyle A.J., Gonzalez-Stawinski G, John R, Jorde U., Russell SD, Conte JV, Aaronson KD, McGee E.C., Cotts WG, DeNofrio D, Pham DT, Farrar D.J., Pagani FD Results of the post-U.S. Food and Drug Administration Study with a continuous flow left ventricular assist device as a bridge to heart transplantation. J Am Coll Card. 2011;57:1890-1898.
26. Holman WL, Kirklin JK, Naftel D.C., Kormos RL, Desvign-Nickens P, Camacho MT, Ascheim DD Infection after implantation of pulsatile mechanical circulatory support devices. J Thorac Cardiovasc Surg. 2010;139:1632-1636.e2.
27. Hussay JC, Parameshwar J, Bannes NR Influence of blood group on mortality and waiting time before heart transplant in the United Kingdom: implications for equity of access. J Heart Lung Transplant. 2007;26:30-33.
28. Demirozu ZT, Radovancevic R, Hochman L.F., Gregoric ID, Letsou GV, Kar B, Bogaev R.C., Frazier OH Arteriovenous malformation and gastrointestinal bleeding in patients with the HeartMate II left ventricular assist device. J Heart Lung Transplant. 2011;30:849-853.
29. Laupacis A, Feeny D, Detsky A.S., Tugwell PX How attractive does a new technology have to be to warrant adoption and utilization? Tentative guidelines for using clinical and economic evaluations. CMAJ. 1992;146:473-481.
30. Miller LW, Pagani FD, Russell S.D., John R., Boyle AJ, Aaronson KD, Conte JV, Naka Y, Mancini D., Delgado RM, MacGillivray TE, Farrar DJ, Frazier OH; HeartMate II Clinical Investigators. Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med. 2007;357:885-896.
31. Sandner SE, Zimpfer D, Zrunek P., Rajek A, Schima H, Dunkler D., Grimm M, Wolner E, Wieselthaler GM Renal function and outcome after continuous flow left ventricular assist device implantation. Ann Thorac Surg. 2009;87:1072-1078.
32. Clegg AJ, Scott DA, Loveman E, Colquitt J.L., Royle P., Bryant J. Clinical and cost-effectiveness of left ventricular assist devices as a bridge to heart transplantation for people with end-stage heart failure: a systematic review and economic evaluation. Eur Heart J. 2006;27:2929-2938.
33. Dew MA, Kormos RL, Winowich S, Harris R.C., Stanford EA, Carozza L, Griffith BP Quality of life outcomes after heart transplantation in individuals bridged to transplant with ventricular assist devices. J Heart Lung Transplant. 2001;20:1199-1212.
34. Moreno SG, Novielli N, Cooper NJ Cost-effectiveness of the implantable HeartMate II left ventricular assist device for patients awaiting heart transplantation. J Heart Lung Transplant. 2012;31:450-458.
35. Worrall J. Evidence: philosophy of science meets medicine. J Eval Clin Pract. 2010;16:356-362.
36. Slaughter MS, Bostic R, Tong K., Russo M, Rogers JG Temporal changes in hospital costs for left ventricular assist device implantation. J Card Surg. 2011;26:535-541.