Predictors of the rate of BMD loss in older men: Findings from the CHAMP study

Osteoporosis International

Volumn 24, Issue 7, 2013, Pages 1951-1963

  Bleicher, K ^a   Cumming, R G ^a   Naganathan, V ^b   Seibel, M J ^b   Blyth, F M ^b   Le Couteur, D G ^b   Handelsman, D J ^b   Creasey, H M ^b   Waite, L M ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

BMC loss; Bone mineral density; Epidemiology; Longitudinal study; Men; Risk factors

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 25 HYDROXYVITAMIN D; ANTIANDROGEN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; LOOP DIURETIC AGENT;

AGED; AGING; ALCOHOL CONSUMPTION; ARTICLE; BODY MOVEMENT; BODY WEIGHT; BONE DENSITY; BONE MINERAL; CLINICAL ASSESSMENT; COGNITION; DRUG USE; DUAL ENERGY X RAY ABSORPTIOMETRY; EXERCISE; FOLLOW UP; GRIP STRENGTH; HIP; HUMAN; KIDNEY DISEASE; LIFESTYLE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MUSCLE STRENGTH; OSTEOLYSIS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; QUESTIONNAIRE; RADIOGRAPHY DEVICE; VERY ELDERLY; VITAMIN BLOOD LEVEL; WALKING;

ABSORPTIOMETRY, PHOTON; AGED; AGED, 80 AND OVER; AGING; BONE DENSITY; DISEASE PROGRESSION; HIP JOINT; HUMANS; LONGITUDINAL STUDIES; MALE; MUSCLE STRENGTH; NEW SOUTH WALES; OSTEOPOROSIS; RISK FACTORS; VITAMIN D; WALKING;

EID: 84879243121     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-012-2226-0     Document Type: Article

References (70)

1. Gullberg B, Johnell O, Kanis J (1997) World-wide projections for hip fracture. Osteoporos Int 7:407-413
2. Cummings SR, Cawthon PM, Ensrud KE, Cauley JA, Fink HA, Orwoll ES (2006) BMD and risk of hip and nonvertebral fractures in older men: a prospective study and comparison with older women. J Bone Miner Res 21:1550-1556
3. Johnell O, Kanis JA, Oden A, Johansson H, De Laet C, Delmas P, Eisman JA, Fujiwara S, Kroger H, Mellstrom D, Meunier PJ, Melton LJ 3rd, O'Neill T, Pols H, Reeve J, Silman A, Tenenhouse A (2005) Predictive value of BMD for hip and other fractures. J Bone Miner Res 20:1185-1194
4. Nguyen ND, Pongchaiyakul C, Center JR, Eisman JA, Nguyen TV (2005) Identification of high-risk individuals for hip fracture: a 14-year prospective study. J Bone Miner Res 20:1921-1928
5. Schuit SCE, van der Klift M, Weel AEAM, de Laet CEDH, Burger H, Seeman E, Hofman A, Uitterlinden AG, van Leeuwen JPTM, Pols HAP (2004) Fracture incidence and association with bone mineral density in elderly men and women: the Rotterdam Study. Bone 34:195-202
6. Henry M, Pasco J, Korn S, Gibson J, Kotowicz M, Nicholson G (2010) Bone mineral density reference ranges for Australian men: Geelong Osteoporosis Study. Osteoporos Int 21:909-917
7. Yoshimura N, Kinoshita H, Danjoh S, Takijiri T, Morioka S, Kasamatsu T, Sakata K, Hashimoto T (2002) Bone loss at the lumbar spine and the proximal femur in a rural japanese community, 1990-2000: the Miyama Study. Osteoporos Int 13:803-808
8. Melton LJ 3rd, Khosla S, Atkinson EJ, O'Connor MK, O'Fallon WM, Riggs BL (2000) Cross-sectional versus longitudinal evaluation of bone loss in men and women. Osteoporos Int 11:592-599
9. Bakhireva LN, Barrett-Connor E, Kritz-Silverstein D, Morton DJ (2004) Modifiable predictors of bone loss in older men: a prospective study. Am J Prev Med 26:436-442
10. Tracy JK, Meyer WA, Flores RH, Wilson PD, Hochberg MC (2005) Racial differences in rate of decline in bone mass in older men: the Baltimore men's osteoporosis study. J Bone Miner Res 20:1228-1234
11. Cawthon PM, Ewing SK, McCulloch CE, Cauley J, Cummings S, Orwoll E (2009) Loss of hip BMD in older men: the osteoporotic fractures in men (MrOS) study. J Bone Miner Res 24:1728-1735
12. Kaptoge S, Reid DM, Scheidt-Nave C, Poor G, Pols HAP, Khaw KT, Felsenberg D, Benevolenskaya LI, Diaz MN, Stepan JJ, Eastell R, Boonen S, Cannata JB, Glueer CC, Crabtree NJ, Kaufman JM, Reeve J (2007) Geographic and other determinants of BMD change in European men and women at the hip and spine. A population-based study from the Network in Europe for Male Osteoporosis (NEMO). Bone 40:662-673
13. Burger H, De Laet C, Van Daele P, Weel A, Witteman J, Hofman A, Pols H (1998) Risk factors for increased bone loss in an elderly population the rotterdam study. Am J Epidemiol 147:871
14. Warming L, Hassager C, Christiansen C (2002) Changes in bone mineral density with age in men and women: a longitudinal study. Osteoporos Int 13:105-112
15. Hannan MT, Felson DT, Dawson-Hughes B, Tucker KL, Cupples LA, Wilson PW, Kiel DP (2000) Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res 15:710-720
16. Kaptoge S, Welch A, McTaggart A, Mulligan A, Dalzell N, Day NE, Bingham S, Khaw KT, Reeve J (2003) Effects of dietary nutrients and food groups on bone loss from the proximal femur in men and women in the 7th and 8th decades of age. Osteoporos Int 14:418-428
17. Dennison E, Eastell R, Fall CH, Kellingray S, Wood PJ, Cooper C (1999) Determinants of bone loss in elderly men and women: a prospective population-based study. Osteoporos Int 10:384-391
18. Jones G, Nguyen T, Sambrook P, Kelly PJ, Eisman JA (1994) Progressive loss of bone in the femoral neck in elderly people: longitudinal findings from the Dubbo osteoporosis epidemiology study. BMJ 309:691-695
19. Slemenda CW, Christian JC, Reed T, Reister TK, Williams CJ, Johnston CC (1992) Long-term bone loss in men: effects of genetic and environmental factors. Ann Intern Med 117:286-291
20. Yoshimura N (2003) Predictive factors for bone loss. Clin Calcium 13:1003-1009
21. Dennison E, Yoshimura N, Hashimoto T, Cooper C (1998) Bone loss in Great Britain and Japan: a comparative longitudinal study. Bone 23:379-382
22. Bleicher K, Cumming RG, Naganathan V, Seibel MJ, Sambrook PN, Blyth FM, Le Couteur D, Handelsman DJ, Creasey H, Waite L (2011) Lifestyle factors, medications and disease influence bone mineral density in older men: findings from the CHAMP study. Osteoporos Int 22:2421-2437
23. National Health and Medical Research Council (2001) Australian Alcohol Guidelines: Health Risks and Benefits, vol. 2010. Commonwealth of Australia Canberra
24. Washburn RA, McAuley E, Katula J, Mihalko SL, Boileau RA (1999) The physical activity scale for the elderly (PASE): evidence for validity. J Clin Epidemiol 52:643-651
25. Fried L, Tangen C, Walston J, Newman A, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop W, Burke G (2001) Frailty in older adults: evidence for a phenotype. Journals of Gerontology Series A: Biological and MedicalSciences 56:146
26. Sherrington C, Lord SR (2005) Reliability of simple portable tests of physical performance in older people after hip fracture. Clin Rehabil 19:496-504
27. Jorm AF (2004) The informant questionnaire on cognitive decline in the elderly (IQCODE): a review. Int Psychogeriatr 16:275-293
28. Cauley JA, Lui LY, Barnes D, Ensrud KE, Zmuda JM, Hillier TA, Hochberg MC, Schwartz AV, Yaffe K, Cummings SR, Newman AB (2009) Successful skeletal aging: a marker of low fracture risk and longevity. The Study of Osteoporotic Fractures (SOF). J Bone Miner Res 24:134-143
29. Lee H, McGovern K, Finkelstein JS, Smith MR (2005) Changes in bone mineral density and body composition during initial and long-term gonadotropin-releasing hormone agonist treatment for prostate carcinoma. Cancer 104:1633-1637
30. Higano CS (2008) Androgen-deprivation-therapy-induced fractures in men with nonmetastatic prostate cancer: what do we really know. Nat Clin Pract Urol 5:24-34
31. Melton LJ, Lieber MM, Atkinson EJ, Achenbach SJ, Zincke H, Therneau TM, Khosla S (2011) Fracture risk in men with prostate cancer: a population-based study. J Bone Miner Res 26:1808-1815
32. Shahinian VB (2005) Risk of fracture after androgen deprivation for prostate cancer. N Engl J Med 352:154-164
33. Abrahamsen B, Nielsen MF, Eskildsen P, Andersen JT, Walter S, Brixen K (2007) Fracture risk in Danish men with prostate cancer: a nationwide register study. BJU Int 100:749-754
34. Taylor LG, Canfield SE, Du XL (2009) Review of major adverse effects of androgen-deprivation therapy in men with prostate cancer. Cancer 115:2388-2399
35. Loke YK, Singh S, Furberg CD (2009) Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis. Can Med Assoc J 180:32-39
36. Zinman B, Haffner SM, Herman WH, Holman RR, Lachin JM, Kravitz BG, Paul G, Jones NP, Aftring RP, Viberti G (2010) Effect of rosiglitazone, metformin, and glyburide on bone biomarkers in patients with type 2 diabetes. J Clin Endocrinol Metab 95:134-142
37. Schwartz AV, Sellmeyer DE, Vittinghoff E, Palermo L, Lecka-Czernik B, Feingold KR, Strotmeyer ES, Resnick HE, Carbone L, Beamer BA, Park SW, Lane NE, Harris TB, Cummings SR (2006) Thiazolidinedione use and bone loss in older diabetic adults. J Clin Endocrinol Metab 91:3349-3354
38. Yaturu S, Bryant B, Jain SK (2007) Thiazolidinedione treatment decreases bone mineral density in type 2 diabetic men. Diabetes Care 30:1574-1576
39. Meier C, Kraenzlin ME, Bodmer M, Jick SS, Jick H, Meier CR (2008) Use of thiazolidinediones and fracture risk. Arch Intern Med 168:820-825
40. Douglas IJ, Evans SJ, Pocock S, Smeeth L (2009) The risk of fractures associated with thiazolidinediones: a self-controlled case-series study. PLoS Med 6:e1000154
41. Mancini T, Mazziotti G, Doga M, Carpinteri R, Simetovic N, Vescovi PP, Giustina A (2009) Vertebral fractures in males with type 2 diabetes treated with rosiglitazone. Bone 45:784-788
42. Cauley JA, Fullman RL, Stone KL, Zmuda JM, Bauer DC, Barrett-Connor E, Ensrud K, Lau EM, Orwoll ES (2005) Factors associated with the lumbar spine and proximal femur bone mineral density in older men. Osteoporos Int 16:1525-1537
43. Yang S, Nguyen ND, Center JR, Eisman JA, Nguyen TV (2011) Association between beta-blocker use and fracture risk: the Dubbo Osteoporosis Epidemiology Study. Bone 48:451-455
44. Wiens M, Etminan M, Gill S, Takkouche B (2006) Effects of antihypertensive drug treatments on fracture outcomes: a meta analysis of observational studies. J Intern Med 260:350-362
45. Reid I (2008) Effects of beta-blockers on fracture risk. J Musculoskelet Neuronal Interact 8:105-110
46. Rejnmark L, Vestergaard P, Heickendorff L, Andreasen F, Mosekilde L (2006) Loop diuretics increase bone turnover and decrease bmd in osteopenic postmenopausal women: results from a randomized controlled study with bumetanide. J Bone Miner Res 21:163-170
47. Lim LS, Fink HA, Kuskowski MA, Taylor BC, Schousboe JT, Ensrud KE (2008) Loop diuretic use and increased rates of hip bone loss in older men: the Osteoporotic Fractures in Men Study. Arch Intern Med 168:735
48. Ishani A, Paudel M, Taylor B, Barrett-Connor E, Jamal S, Canales M, Steffes M, Fink H, Orwoll E, Cummings S, Ensrud K (2008) Renal function and rate of hip bone loss in older men: the Osteoporotic Fractures in Men Study. Osteoporos Int 19:1549-1556
49. Jassal SK, von Muhlen D, Barrett-Connor E (2007) Measures of renal function, BMD, bone loss, and osteoporotic fracture in older adults: the Rancho Bernardo Study. J Bone Miner Res 22:203-210
50. Jamal SA, Swan VJD, Brown JP, Hanley DA, Prior JC, Papaioannou A, Langsetmo L, Josse RG (2010) Kidney function and rate of bone loss at the hip and spine: the Canadian multicentre osteoporosis study. American journal of kidney diseases: the official journal of the National Kidney Foundation 55:291-299
51. Jamal SA (2010) Bone mass measurements in men and women with chronic kidney disease. Curr Opin Nephrol Hypertens 19:343-348
52. Sheu Y, Cauley J, Wheeler V, Patrick A, Bunker C, Ensrud K, Orwoll E, Zmuda J (2010) Age-related decline in bone density among ethnically diverse older men. Osteoporosis International. 1-7
53. Ensrud KE, Palermo L, Black DM, Cauley J, Jergas M, Orwoll ES, Nevitt MC, Fox KM, Cummings SR (1995) Hip and calcaneal bone loss increase with advancing age: longitudinal results from the study of osteoporotic fractures. J Bone Miner Res 10:1778-1787
54. Palombaro KM (2005) Effects of walking-only interventions on bone mineral density at various skeletal sites: a meta-analysis. J Geriatr Phys Ther 28:102
55. Shea B, Bonaiuti D, Iovine R, Negrini S, Robinson V, Kemper H, Wells G, Tugwell P, Cranney A (2004) Cochrane review on exercise for preventing and treating osteoporosis in postmenopausal women. Europa Medicophysica 40:199-210
56. Huuskonen J, Väisänen SB, Kröger H, Jurvelin JS, Alhava E, Rauramaa R (2001) Regular physical exercise and bone mineral density: a four-year controlled randomized trial in middle-aged men. The DNASCO Study. Osteoporosis International 12:349-355
57. Martyn-St James M, Carroll S (2008) Meta-analysis of walking for preservation of bone mineral density in postmenopausal women. Bone 43:521-531
58. Chen JS, Cameron ID, Cumming RG, Lord SR, March LM, Sambrook PN, Simpson JM, Seibel MJ (2006) Effect of age-related chronic immobility on markers of bone turnover. J Bone Miner Res 21:324-331
59. Wagner H, Melhus H, Gedeborg R, Pedersen NL, Michaelsson K (2009) Simply ask them about their balance - future fracture risk in a nationwide cohort study of twins. Am J Epidemiol 169:143-149
60. Bleicher K, Cumming R, Naganathan V, Seibel M, Sambrook P, Blyth F, Le Couteur D, Handelsman D, Creasey H, Waite L (2010) Lifestyle factors, medications, and disease influence bone mineral density in older men: findings from the CHAMP study. Osteoporos Int 22:2421-2437
61. Knoke JD, Barrett-Connor E (2003) Weight loss: a determinant of hip bone loss in older men and women: the Rancho Bernardo study. Am J Epidemiol 158:1132-1138
62. Prentice A, Parsons T, Cole T (1994) Uncritical use of bone mineral density in absorptiometry may lead to size-related artifacts in the identification of bone mineral determinants. Am J Clin Nutr 60:837
63. Cranney A, Horsley T, O'Donnell S, Weiler H, Puil L, Ooi D, Atkinson S, Ward L, Moher D, Hanley D (2007) Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess 158:1-235
64. Chung M, Balk EM, Brendel M, Ip S, Lau J, Lee J, Lichtenstein A, Patel K, Raman G, Tatsioni A, Terasawa T, Trikalinos TA (2009) Vitamin D and calcium: Systematic review of health outcomes. Evidence Report/Technology Assessment No. 183. (Prepared by Tufts Evidence-based Practice Center under Contract No. 290-2007-10055-I). AHRQ Publication No. 09-E015, Rockville, MD:. Agency for Healthcare Research and Quality
65. Ensrud KE, Taylor BC, Paudel ML, Cauley JA, Cawthon PM, Cummings SR, Fink HA, Barrett-Connor E, Zmuda JM, Shikany JM, Orwoll ES (2009) Serum 25-hydroxyvitamin D levels and rate of hip bone loss in older men. J Clin Endocrinol Metab 94:2773-2780
66. Pasco JA, Henry MJ, Nicholson GC, Brennan SL, Kotowicz MA (2009) Behavioural and physical characteristics associated with vitamin D status in women. Bone 44:1085-1091
67. Cranney A, Weiler HA, O'Donnell S, Puil L (2008) Summary of evidence-based review on vitamin D efficacy and safety in relation to bone health. Am J Clin Nutr 88:513S-519S
68. Cumming RG, Handelsman D, Seibel MJ, Creasey H, Sambrook P, Waite L, Naganathan V, Le Couteur D, Litchfield M (2009) Cohort profile: the Concord Health and Ageing in Men Project (CHAMP). Int J Epidemiol 38:374-378
69. Holden C, McLaclan R, Pitts M (2005) Men in australia telephone survey(mates): a national survey of the reproductive health and concerns of middle-aged and older Australian men. Lancet 366:218-224
70. He Y, Davis JW, Ross PD, Wasnich RD (1993) Declining bone loss rate variability with increasing follow-up time. Bone Miner 21:119-128