Anal squamous intraepithelial lesions are frequent among young HIV-infected men who have sex with men followed up at the Spanish AIDS Research Network Cohort (CoRIS-HPV)

International Journal of Cancer

Volumn 133, Issue 5, 2013, Pages 1164-1172

  González, Cristina ^a   Torres, Montserrat ^b   Benito, Amparo ^c   Del Romero, Jorge ^d   Rodríguez, Carmen ^d   Fontillón, María ^e   Trastoy, Mónica ^e   Viciana, Pompeyo ^e   Del Amo, Julia ^a   Ortiz, Marta ^b   Hernández Novoa, Beatriz ^c  

^a CARLOS III INSTITUTE OF HEALTH   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

^d CENTRO SANITARIO SANDOVAL   (Spain)

^e HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

anal; cytology; HIV; HPV; squamous intraepithelial lesion

Indexed keywords

ANTIRETROVIRUS AGENT;

ADULT; AGE DISTRIBUTION; ANAL LIQUID CYTOLOGY; ANAL SQUAMOUS INTRAEPITHELIAL LESION; ANUS DISEASE; ARTICLE; ATYPICAL SQUAMOUS CELLS OF UNCERTAIN SIGNIFICANCE; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; CONCURRENT SEXUAL PARTNERSHIP; CONTROLLED STUDY; CYTODIAGNOSIS; DISEASE ASSOCIATION; EDUCATIONAL STATUS; FOLLOW UP; GENOTYPE; GEOGRAPHIC ORIGIN; HIGH GRADE SQUAMOUS INTRAEPITHELIAL LESION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LOW GRADE SQUAMOUS INTRAEPITHELIAL LESION; MAJOR CLINICAL STUDY; MALE; MEN WHO HAVE SEX WITH MEN; PAPILLOMAVIRUS INFECTION; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SMOKING; SPAIN;

ANAL; CYTOLOGY; HIV; HPV; SQUAMOUS INTRAEPITHELIAL LESION;

ADULT; ANUS NEOPLASMS; COHORT STUDIES; FOLLOW-UP STUDIES; HIV INFECTIONS; HOMOSEXUALITY, MALE; HUMANS; LOGISTIC MODELS; MALE; PAPILLOMAVIRIDAE; PRECANCEROUS CONDITIONS; PREVALENCE;

EID: 84879236687     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28102     Document Type: Article

References (50)

1. Frisch M, Glimelius B, van den Brule AJ, et al. Sexually transmitted infection as a cause of anal cancer. N Engl J Med 1997; 337: 1350-8.
2. Lacey HB, Wilson GE, Tilston P, et al. A study of anal intraepithelial neoplasia in HIV positive homosexual men. Sex Transm Infect 1999; 75: 172-7.
3. Palefsky JM, Holly EA, Ralston ML, et al. Prevalence and risk factors for human papillomavirus infection of the anal canal in human immunodeficiency virus (HIV)-positive and HIV-negative homosexual men. J Infect Dis 1998; 177: 361-7.
4. Sirera G, Videla S, Pinol M, et al. High prevalence of human papillomavirus infection in the anus, penis and mouth in HIV-positive men. AIDS 2006; 20: 1201-4.
5. de Pokomandy A, Rouleau D, Ghattas G, et al. Prevalence, clearance, and incidence of anal human papillomavirus infection in HIV-infected men: the HIPVIRG cohort study. J Infect Dis 2009; 199: 965-73.
6. Palefsky JM, Holly EA, Efirdc JT, et al. Anal intraepithelial neoplasia in the highly active antiretroviral therapy era among HIV-positive men who have sex with men. AIDS 2005; 19: 1407-14.
7. Piketty C, Darragh TM, Heard I, et al. High prevalence of anal squamous intraepithelial lesions in HIV-positive men despite the use of highly active antiretroviral therapy. Sex Transm Dis 2004; 31: 96-9.
8. Darwich L, Cañadas M, Videla S, et al. Condylomata, cytological abnormalities and human papillomavirus infection in the anal canal in HIV-infected men. HIV Med 2012; 13: 549-57.
9. Ortiz M, Torres M, González C, et al. High-risk HPV (HR-HPV) prevalence by HIV-1 status in Spanish men who have sex with men (MSM) in an out patient sexually transmitted diseases clinic and in a prospective cohort of HIV-positive MSM belonging to Spanish Multicenter Cohort (CoRIS), Presented at the 17th Conference on Retroviruses and Opportunistic Infections (CROI), San Francisco, CA, February 16-19, 2010.
10. Bower M, Powles T, Newsom-Davis T, et al. HIV-associated anal cancer: has highly active antiretroviral therapy reduced the incidence or improved the outcome? J Acquir Immune Defic Syndr 2004; 37: 1563-5.
11. D'Souza G, Wiley DJ, Li X, et al. Incidence and epidemiology of anal cancer in the multicenter AIDS cohort study. J Acquir Immune Defic Syndr 2008; 48: 491-9.
12. Patel P, Hanson DL, Sullivan PS, et al. Incidence of types of cancer among HIV-infected persons compared with the general population in the United States, 1992-2003. Ann Intern Med 2008; 148: 728-36.
13. Piketty C, Selinger-Leneman H, Grabar S, et al. Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy. AIDS 2008; 22: 1203-11.
14. Chiao EY, Krown SE, Stier EA, et al. A population-based analysis of temporal trends in the incidence of squamous anal canal cancer in relation to the HIV epidemic. J Acquir Immune Defic Syndr 2005; 40: 451-5.
15. Diamond C, Taylor TH, Aboumrad T, et al. Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy. Sex Transm Dis 2005; 32: 314-20.
16. Frisch M, Biggar RJ, Goedert JJ,. Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Natl Cancer Inst 2000; 92: 1500-10.
17. Lanoy E, Spano JP, Bonnet F, et al. The spectrum of malignancies in HIV-infected patients in 2006 in France: the ONCOVIH study. Int J Cancer 2011; 129: 467-75.
18. Melbye M, Cote TR, Kessler L, et al. High incidence of anal cancer among AIDS patients. The AIDS/Cancer Working Group. Lancet 1994; 343: 636-9.
19. Panther LA, Schlecht HP, Dezube BJ,. Spectrum of human papillomavirus-related dysplasia and carcinoma of the anus in HIV-infected patients. AIDS Read 2005; 15: 79-82, 85-6, 88, 91.
20. Crum-Cianflone NF, Hullsiek KH, Marconi VC, et al. Anal cancers among HIV-infected persons: HAART is not slowing rising incidence. AIDS 2010; 24: 535-43.
21. Engels EA, Biggar RJ, Hall HI, et al. Cancer risk in people infected with human immunodeficiency virus in the United States. Int J Cancer 2008; 123: 187-94.
22. Hessol NA, Pipkin S, Schwarcz S, et al. The impact of highly active antiretroviral therapy on non-AIDS-defining cancers among adults with AIDS. Am J Epidemiol 2007; 165: 1143-53.
23. Seaberg EC, Wiley D, Martinez-Maza O, et al. Cancer incidence in the multicenter aids cohort study before and during the HAART era: 1984 to 2007. Cancer 2010; 116: 5507-16.
24. van Leeuwen MT, Vajdic CM, Middleton MG, et al. Continuing declines in some but not all HIV-associated cancers in Australia after widespread use of antiretroviral therapy. AIDS 2009; 23: 2183-90.
25. Simard EP, Pfeiffer RM, Engels EA,. Cumulative incidence of cancer among individuals with acquired immunodeficiency syndrome in the United States. Cancer 2011; 117: 1089-96.
26. Frisch M, Biggar RJ, Engels EA, et al. Association of cancer with AIDS-related immunosuppression in adults. JAMA 2001; 285: 1736-45.
27. Palefsky JM,. Anal human papillomavirus infection and anal cancer in HIV-positive individuals: an emerging problem. AIDS 1994; 8: 283-95.
28. Palefsky JM, Holly EA, Ralston ML, et al. Anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual and bisexual men: prevalence and risk factors. J Acquir Immune Defic Syndr Hum Retrovirol 1998; 17: 320-6.
29. Chin-Hong PV, Berry JM, Cheng SC, et al. Comparison of patient- and clinician-collected anal cytology samples to screen for human papillomavirus-associated anal intraepithelial neoplasia in men who have sex with men. Ann Intern Med 2008; 149: 300-6.
30. Conley L, Bush T, Darragh TM, et al. Factors associated with prevalent abnormal anal cytology in a large cohort of HIV-infected adults in the United States. J Infect Dis 2010; 202: 1567-76.
31. Friedman HB, Saah AJ, Sherman ME, et al. Human papillomavirus, anal squamous intraepithelial lesions, and human immunodeficiency virus in a cohort of gay men. J Infect Dis 1998; 178: 45-52.
32. Li AH, Phanuphak N, Sahasrabuddhe VV, et al. Anal squamous intraepithelial lesions among HIV positive and HIV negative men who have sex with men in Thailand. Sex Transm Infect 2009; 85: 503-7.
33. Palefsky JM, Holly EA, Ralston ML, et al. Anal cytological abnormalities and anal HPV infection in men with Centers for Disease Control group IV HIV disease. Genitourin Med 1997; 73: 174-80.
34. Wilkin TJ, Palmer S, Brudney KF, et al. Anal intraepithelial neoplasia in heterosexual and homosexual HIV-positive men with access to antiretroviral therapy. J Infect Dis 2004; 190: 1685-91.
35. de Pokomandy A, Rouleau D, Ghattas G, et al. HAART and progression to high-grade anal intraepithelial neoplasia in men who have sex with men and are infected with HIV. Clin Infect Dis 2011; 52: 1174-81.
36. Salit IE, Lytwyn A, Raboud J, et al. The role of cytology (Pap tests) and human papillomavirus testing in anal cancer screening. AIDS 2010; 24: 1307-13.
37. Weis SE, Vecino I, Pogoda JM, et al. Prevalence of anal intraepithelial neoplasia defined by anal cytology screening and high-resolution anoscopy in a primary care population of HIV-infected men and women. Dis Colon Rectum 2011; 54: 433-41.
38. De Vuyst H, Clifford GM, Nascimento MC, et al. Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis. Int J Cancer 2009; 124: 1626-36.
39. Salit IE, Tinmouth J, Chong S, et al. Screening for HIV-associated anal cancer: correlation of HPV genotypes, p16, and E6 transcripts with anal pathology. Cancer Epidemiol Biomarkers Prev 2009; 18: 1986-92.
40. Palefsky JM, Holly EA, Hogeboom CJ, et al. Virologic, immunologic, and clinical parameters in the incidence and progression of anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual men. J Acquir Immune Defic Syndr Hum Retrovirol 1998; 17: 314-19.
41. Palefsky JM, Holly EA, Ralston ML, et al. High incidence of anal high-grade squamous intra-epithelial lesions among HIV-positive and HIV-negative homosexual and bisexual men. AIDS 1998; 12: 495-503.
42. Payam A, Shiramizu B, Shikuma C, et al. HIV-associated anal dysplasia: experience from a multiethnic-HIV clinic in Hawaii. J Health Care Poor Underserved 2011; 22: 16-22.
43. Scott H, Khoury J, Moore BA, et al. Routine anal cytology screening for anal squamous intraepithelial lesions in an urban HIV clinic. Sex Transm Dis 2008; 35: 197-202.
44. Del Amo J, González C, Geskus RB, et al.; on behalf of CoRIS-HPV Study Group. What drives the number of high risk human papillomavirus types in the anal canal in HIV-positive men who have sex with men? J Infect Dis, in press.
45. Chin-Hong PV, Vittinghoff E, Cranston RD, et al. Age-specific prevalence of anal human papillomavirus infection in HIV-negative sexually active men who have sex with men: the EXPLORE study. J Infect Dis 2004; 190: 2070-6.
46. Nyitray AG, Carvalho da Silva RJ, Baggio ML, et al. Age-specific prevalence of and risk factors for anal human papillomavirus (HPV) among men who have sex with women and men who have sex with men: the HPV in men (HIM) study. J Infect Dis 2011; 203: 49-57.
47. Vajdic CM, van Leeuwen MT, Jin F, et al. Anal human papillomavirus genotype diversity and co-infection in a community-based sample of homosexual men. Sex Transm Infect 2009; 85: 330-5.
48. Palefsky JM, Shiboski S, Moss A,. Risk factors for anal human papillomavirus infection and anal cytologic abnormalities in HIV-positive and HIV-negative homosexual men. J Acquir Immune Defic Syndr 1994; 7: 599-606.
49. Daling JR, Sherman KJ,. Relationship between human papillomavirus infection and tumours of anogenital sites other than the cervix. IARC Sci Publ 1992: 223-41.
50. Darragh TM, Tokugawa D, Castle PE, et al. Interrater agreement of anal cytology. Cancer Cytopathol 2013; 121: 72-8.