Effects of vinpocetine on random skin flap survival in rats

Journal of Reconstructive Microsurgery

Volumn 29, Issue 6, 2013, Pages 393-397

  Xiao Xiao, Tao ^a   Sen Min, Wu ^a   Ding Sheng, Lin ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

free radical; random skin flap; survival; vascular endothelial growth factor; vinpocetine

Indexed keywords

MALONALDEHYDE; SUPEROXIDE DISMUTASE; VASCULOTROPIN; VINPOCETINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GRAFT NECROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKIN FLAP SURVIVAL;

ANIMALS; DISEASE MODELS, ANIMAL; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; MALE; MALONDIALDEHYDE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; REPERFUSION INJURY; SENSITIVITY AND SPECIFICITY; SKIN TRANSPLANTATION; SUPEROXIDE DISMUTASE; SURGICAL FLAPS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VINCA ALKALOIDS;

EID: 84879218616     PISSN: 0743684X     EISSN: 10988947     Source Type: Journal    
DOI: 10.1055/s-0033-1343834     Document Type: Article

References (18)

1. Yang M., Sheng L., Li H., Weng R., Li Q. F. Improvement of the skin flap survival with the bone marrow-derived mononuclear cells transplantation in a rat model. Microsurgery: 2010; 30 4 275 281
2. Patyar S., Prakash A., Modi M., Medhi B. Role of vinpocetine in cerebrovascular diseases. Pharmacol Rep: 2011; 63 3 618 628
3. Kelly C. P., Gupta A., Keskin M., Jackson I. T. A new design of a dorsal flap in the rat to study skin necrosis and its prevention. J Plast Reconstr Aesthet Surg: 2010; 63 9 1553 1556
4. Kelly C. P., Gupta A., Keskin M., Jackson I. T. A new design of a dorsal flap in the rat to sutdy skin necrosis and its prevention. Plast Reconstr Aesthet Surg: 2010; 63 9 1553 1556
5. Ozkan O., Ozgentas H. E. Combination of rat vest, teeth shortening, and nail cutting to prevent autocannibalization and protect surgical flaps. Plast Reconstr Surg: 2006; 117 5 1671
6. Mandriota S. J., Pyke C., Di Sanza C., Quinodoz P., Pittet B., Pepper M. S. Hypoxia-inducible angiopoietin-2 expression is mimicked by iodonium compounds and occurs in the rat brain and skin in response to systemic hypoxia and tissue ischemia. Am J Pathol: 2000; 156 6 2077 2089
7. Chen Z., Wang T., Cai L., et al. Clinicopathological significance of non-small cell lung cancer with high prevalence of Oct-4 tumor cells. J Exp Clin Cancer Res: 2012; 31 1 10
8. Ozkan F., Senayli Y., Ozyurt H., Erkorkmaz U., Bostan B. Antioxidant Effects of Propofol on Tourniquet-Induced Ischemia-Reperfusion Injury: An Experimental Study. J Surg Res: 2012; 176 2 601 607
9. Valikovics A. [Investigation of the effect of vinpocetine on cerebral blood flow and cognitive functions]. Ideggyogy Sz: 2007; 60 7-8 301 310
10. Zhang F., Fischer K., Komorowska-Timek E., et al. Improvement of skin paddle survival by application of vascular endothelial growth factor in a rat TRAM flap model. Ann Plast Surg: 2001; 46 3 314 319
11. Vourtsis S. A., Spyriounis P. K., Agrogiannis G. D., Ionac M., Papalois A. E. VEGF application on rat skin flap survival. J Invest Surg: 2012; 25 1 14 19
12. Cui J., Lui L., Zou J., et al. Protective effect of endogenous hydrogen sulfide against oxidative stress in gastric ischemia-reperfusion injury. Exp Ther Med: 2013; 5 3 689 694
13. Sun L. J., Li Y. J., Shi J. S., Wang X., Wang X. Protective effects of ligustrazine on ischemia-reperfusion injury in rat kidneys. Microsurgery: 2002; 22 8 343 346
14. Stolc S. Indole derivatives as neuroprotectants. Life Sci: 1999; 65 18-19 1943 1950
15. Jeon K. I., Xu X., Aizawa T., et al. Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proc Natl Acad Sci U S A: 2010; 107 21 9795 9800
16. Medina A. E. Vinpocetine as a potent antiinflammatory agent. Proc Natl Acad Sci U S A: 2010; 107 22 9921 9922
17. Sitges M., Aldana B. I., Chiu L. M., Nekrassov V. Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings. Neurochem Res: 2009; 34 3 470 479
18. Sitges M., Galván E., Nekrassov V. Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes. Neurochem Int: 2005; 46 7 533 540