Airway and pulmonary vascular measurements using contrast-enhanced micro-CT in rodents

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 12, 2013, Pages

  Counter, W B ^a   Wang, I Q ^a   Farncombe, T H ^a   Labiris, N R ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Airway nomenclature; Computed tomography; Contrast agents; Pulmonary circulation

Indexed keywords

IOHEXOL; LEAD CHROMATE;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL STRUCTURES; ANIMAL TISSUE; ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CT SPECT SCANNER; DISEASE COURSE; FLOW RATE; INFUSION PUMP; INTRARATER RELIABILITY; LUNG BLOOD VESSEL; LUNG CIRCULATION; LUNG STRUCTURE; MALE; MEASUREMENT; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VEIN; RAT; VASCULAR PATENCY;

AIRWAY NOMENCLATURE; COMPUTED TOMOGRAPHY; CONTRAST AGENTS; PULMONARY CIRCULATION;

ALGORITHMS; ANIMALS; CAPILLARIES; CONTRAST MEDIA; IMAGING, THREE-DIMENSIONAL; LUNG; MALE; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; PULMONARY ARTERY; PULMONARY VEINS; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; RATS; RATS, SPRAGUE-DAWLEY; X-RAY MICROTOMOGRAPHY;

EID: 84879186416     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00281.2012     Document Type: Article

References (44)

1. Al-Kofahi Y, Dowell N, Pace C, Shain W, Turner JN, Roysam B. Improved Detection of Branching Points in Algorithms for Automated Neuron Tracing from 3D Confocal Images. Cytometry Part A 73: 36-43, 2008
2. Artaechevarria X, Perez-Martin D, Ceresa C, Biurrun G, Blanco D, Montuenga LM, Ginneken B, Ortiz-de-Solorzano C, Munoz-Barrutia A. Airway segmentation and analysis for the study of mouse models of lung disease using micro-CT. Phys Med Biol 54: 7009-7024, 2009
3. Aykac D, Hoffman EA, McLennan G, Reinhardt JM. Segmentation and analysis of the human airway tree from three-dimensional X-ray CT images. IEEE Trans Med Imag 22: 8, 2003
4. Einstein DR, Neradilak B, Pollisar N, Minard KR, Wallis C, Fanucchi M, Carson JP, Kuprat AP, Kabilan S, Jacob RE, Corley RA. An automated self-similarity analysis of the pulmonary tree of the Sprague- Dawley rat. Anat Rec 291: 1628-1648, 2008
5. Fabijanska A. Two-pass region growing algorithm for segmenting airway tree from MDCT chest scans. Comput Med Imag Graph 33: 537-546, 2009
6. Fetita CI, Preteux F, Beigelman-Aubry C, Grenier P. Pulmonary airways: 3-D reconstruction from multislice CT and clinical investigation. IEEE Trans Med Imag 23: 11, 2004
7. Grabherr S, Hess A, Karolczak M, Thali MJ, Friess SD, Kalender WA, Dirnhofer R, Djonov V. Angiofil-mediated visualization of the vascular system by microcomputed tomography: a feasibility study. Microscopy Res Technique 71: 551-556, 2008
8. Hislop A, Reid L. Normal structure and dimensions of the pulmonary arteries in the rat. J Anat 125: 71-83, 1978
9. Horsfield K. Diameters, generations, and orders of branches in the bronchial tree. J Appl Physiol 60: 1089-1097, 1990
10. Jiang G, Gu L. An automatic and fast centerline extraction algorithm for virtual colonoscopy. IEEE Eng Med Biol Sci 5: 5149-5152, 2005
11. Jiang H, Alperin N. A new automatic skeletonization algorithm for 3d vascular volumes. IEEE Eng Med Biol Sci 2: 1565-1568, 2004
12. Jiang ZL, Kassab GS, Fung YC. Diameter-defined Stahler system and connectivity matrix of the pulmonary arterial tree. J Appl Physiol 76: 882-892, 1994
13. Johnson KA. Imaging techniques for small animal imaging models of pulmonary disease: micro-CT. Toxicol Pathol 35: 59-64, 2007
14. Karau KL, Molthen RC, Dhyani A, Haworth ST, Hanger CC, Roerig DL, Johnson RH, Dawson CA. Pulmonary arterial morphometry from microfocal X-ray computed tomography. Am J Physiol Heart Circ Physiol 281: H2747-H2756, 2001
15. Kindlmann GL, Weinstein DM, Jones GM, Johnson CR, Capecchi MR, Keller C. Practical vessel imaging by computed tomography in live transgenic mouse models for human tumours. Mol Imaging 4: 417-424, 2005
16. Kiraly AP, Higgins WE, McLennan G, Hoffman EA, Reinhardt JM. Three-dimensional human airway segmentation methods for clinical virtual bronchoscopy. Acad Radiol 9: 1153-1168, 2002
17. Kline TL, Zamir M, Ritman EL. Accuracy of microvascular measurements obtained from micro-CT images. Ann Biomed Eng 38: 2851-2864, 2010
18. Lee D, Fanucchi MV, Plopper CG, Fung J, Wexler AS. Pulmonary architecture in the conducting regions of six rats. Anat Rec 291: 916-926, 2008
19. Lesage D, Angelini ED, Bloch I, Funka-Lea G. A review of 3D vessel lumen segmentation techniques: Models, features and extraction schemes. Med Image Anal 13: 819-845, 2009
20. Levitzky MG. Pulmonary Physiology. New York, NY: Magraw-Hill, 2007
21. Maddah M, Soltanian-Zadeh H, Afzali-Kusha A. Snake modeling and distance transform approach to vascular centerline extraction and quantification. Comput Med Imag Graphics 27: 503-512, 2003
22. Molthen RC, Karau KL, Dawson CA. Quantitative models of the rat pulmonary arterial tree morphometry applied to hypoxia-induced arterial remodelling. J Appl Physiol 97: 2372-2384, 2004
23. Palagyi K, Tschirren J, Hoffman EA, Sonka M. Quantitative analysis of pulmonary airway tree structures. Comput Biol Med 36: 974-996, 2006
24. Pannu HK, Thompson RE, Phelps J, Magee CA, Fishman EK. Optimal contrast agents for vascular imaging on computed tomography: iodixanol versus iohexol. Acad Radiol 12: 576-584, 2005
25. Phalen RF, Yeh HC, Schum GM, Raabe G. Application of an idealized model to morphometry of the mammalian tracheobronchial tree. Anat Rec 190: 167-176, 1978
26. Phillips CG, Kaye SR. Diameter-based analysis of the branching geometry of four mammalian bronchial trees. Respir Physiol 102: 303-316 1995
27. Razavi H, Dusch MN, Zarafshar CA, Taylor CA, Feinstein JA. A method for quantitative characterization of growth in the 3-D structure of rat pulmonary arteries. Microvasc Rese 83: 146-153, 2012
28. Ritman EL. Micro-computed tomography of the lungs and pulmonaryvascular system. Proc Am Thorac Soc 2: 477-480, 2005
29. Sera T, Fujioka H, Yokota H, Makinouchi A, Himeno R, Schroter RC, Tanishita K. Three-dimensional visualization and morphometry of small airways from microfocal X-ray computed tomography. J Biomechanics 36: 1587-1594, 2003
30. Shi L, Thiesse J, McLennan G, Hoffman EA, Reinhardt JM. Threedimensional murine airway segmentation in micro-CT images. Proc SPIE 6511: 651105-651111, 2007
31. Sorantin E, Halmai C, Erdohelyi B, Palagyi K, Nyul LG, Olle K, Geiger B, Lindbichler F, Friedrich G, Kiesler K. Spiral-CT-based assessment of tracheal stenoses using 3-D-skeletonization. IEEE Trans Med Imaging 21: 3, 2002
32. Tawhai MH, Hunter P, Tschirren J, Reinhardt J, McLennan G, Hoffman EA. CT-based geometry analysis and finite element models of the human and ovine bronchial tree. J Appl Physiol 97: 2310-2321, 2004
33. Thiesse J, Namati E, Sieren JC, Smith AR, Reinhardt JM, Hoffman EA, McLennan G. Lung structure phenotype variation in inbred mouse strains revealed through in vivo micro-CT imaging. J Appl Physiol 109: 1960-1968, 2010
34. Tschirren J, Hoffman EA, McLennan G, Sonka M. Segmentation and quantitative analysis of intrathoracic airway trees from computed tomography images. Proc Am Thorac Soc 2: 484-487, 2005
35. Tshirren J, Hoffman EA, McLennan G, Sonka M. Intrathoracic airway trees: segmentation and airway morphology analysis from low-dose CT scans. IEEE Trans Med Imaging 24: 1529-1539, 2005
36. Vasilescu DM, Knudsen L, Ochs M, Weibel ER, Hoffman EA. Optimized murine lung preparation for detailed structural evaluation via micro-computed tomography. J Appl Physiol 112: 159-166, 2012
37. Walker WF, Homberger DG. Anatomy & Dissection of the Rat. New York, NY: Freeman, 1997
38. Wallau BR, Schmitz A, Perry SF. Lung morphology in rodents (mammalia, rodentia) and its implications for systematics. J Morphol 246: 228-248, 2000
39. Weibel ER. Morphometry of the Human Lung. Berlin, Germany: Springer, 1963
40. Wilson WL, Mullen M, Olley PM, Rabinovitch M. Hyperoxia-induced pulmonary vascular and lung abnormalities in young rats and potential for recovery. Pediatr Res 19: 1059-1067, 1985
41. Yeh HC, Schum GM, Duggan MT. Anatomic models of the tracheobronchial and pulmonary regions of the rat. Anat Rec 195: 483-492, 1979
42. Yi D, Hayward V. Skeletonization of volumetric angiograms for display. Comput Methods Biomechanics Biomed Eng 5: 329-341, 2002
43. Zheng B, Leader JK, McMurray JM, Park SC, Fuhrman CR, Gur D, Sciurba FC. Automated detection and quantitative assessment of pulmonary airways depicted on CT images. Med Phys 34: 2844-2852, 2007
44. Zhou YQ, Davidson L, Henkelman RM, Nieman BJ, Foster FS, Yu LX, Chen XJ. Ultrasound-guided left-ventricular catheterization: a novel method of whole mouse perfusion. Lab Invest 84: 385-389, 2004.