메뉴 건너뛰기




Volumn 20, Issue 2, 2013, Pages 185-196

Gene capture coupled to high-throughput sequencing as a strategy for targeted metagenome exploration

Author keywords

Subunit of the methyl coenzyme M reductase; 454 Pyrosequencing; Metagenomics; Microbial diversity; Sequence capture

Indexed keywords

DNA FRAGMENT; OXIDOREDUCTASE;

EID: 84879174400     PISSN: 13402838     EISSN: 17561663     Source Type: Journal    
DOI: 10.1093/dnares/dst001     Document Type: Article
Times cited : (42)

References (57)
  • 3
    • 0028946084 scopus 로고
    • Phylogenetic identification and in situ detection of individual microbial cells without cultivation
    • Amann, R., Ludwig, W. and Schleifer, K.-H. 1995, Phylogenetic identification and in situ detection of individual microbial cells without cultivation, Microbiol. Rev., 59, 143-69.
    • (1995) Microbiol. Rev. , vol.59 , pp. 143-169
    • Amann, R.1    Ludwig, W.2    Schleifer, K.-H.3
  • 4
    • 33947221422 scopus 로고    scopus 로고
    • Environmental shotgun sequencing: Its potential and challenges for studying the hidden world of microbes
    • Eisen, J.A. 2007, Environmental shotgun sequencing: Its potential and challenges for studying the hidden world of microbes, PLoS Biol., 5, e82.
    • (2007) PLoS Biol. , vol.5
    • Eisen, J.A.1
  • 5
    • 0032192790 scopus 로고    scopus 로고
    • Molecular biological access to the chemistry of unknown soil microbes: A new frontier for natural products
    • Handelsman, J., Rondon, M.R., Brady, S.F., Clardy, J. and Goodman, R.M. 1998, Molecular biological access to the chemistry of unknown soil microbes: A new frontier for natural products, Chem. Biol., 5, R245-249.
    • (1998) Chem. Biol. , vol.5
    • Handelsman, J.1    Rondon, M.R.2    Brady, S.F.3    Clardy, J.4    Goodman, R.M.5
  • 6
    • 48749117805 scopus 로고    scopus 로고
    • Metagenomic signatures of the Peru Margin subseafloor biosphere show a genetically distinct environment
    • Biddle, J.F., Fitz-Gibbon, S., Schuster, S.C., Brenchley, J.E. and House, C.H. 2008, Metagenomic signatures of the Peru Margin subseafloor biosphere show a genetically distinct environment, Proc. Natl. Acad. Sci. USA, 105, 10583-88.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 10583-10588
    • Biddle, J.F.1    Fitz-Gibbon, S.2    Schuster, S.C.3    Brenchley, J.E.4    House, C.H.5
  • 7
    • 20244376755 scopus 로고    scopus 로고
    • Comparative metagenomics of microbial communities
    • Tringe, S.G., von Mering, C., Kobayashi, A., et al. 2005, Comparative metagenomics of microbial communities, Science, 308, 554-7.
    • (2005) Science , vol.308 , pp. 554-557
    • Tringe, S.G.1    Von Mering, C.2    Kobayashi, A.3
  • 8
    • 10944226351 scopus 로고    scopus 로고
    • Metagenomics: Genomic analysis of microbial communities
    • Riesenfeld, C.S., Schloss, P.D. and Handelsman, J. 2004, Metagenomics: Genomic analysis of microbial communities, Annu. Rev. Genet., 38, 525-52.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 525-552
    • Riesenfeld, C.S.1    Schloss, P.D.2    Handelsman, J.3
  • 9
    • 84855295480 scopus 로고    scopus 로고
    • Targeted metagenomics: A high-resolution metagenomics approach for specific gene clusters in complex microbial communities
    • Suenaga, H. 2011, Targeted metagenomics: A high-resolution metagenomics approach for specific gene clusters in complex microbial communities, Environ. Microbiol., 14, 13-22.
    • (2011) Environ. Microbiol. , vol.14 , pp. 13-22
    • Suenaga, H.1
  • 10
    • 33745595097 scopus 로고    scopus 로고
    • Using pyrosequencing to shed light on deep mine microbial ecology
    • Edwards, R.A., Rodriguez-Brito, B., Wegley, L., et al. 2006, Using pyrosequencing to shed light on deep mine microbial ecology, BMC Genomics, 7, 57.
    • (2006) BMC Genomics , vol.7 , pp. 57
    • Edwards, R.A.1    Rodriguez-Brito, B.2    Wegley, L.3
  • 11
    • 39649117755 scopus 로고    scopus 로고
    • The impact of next-generation sequencing technology on genetics
    • Mardis, E.R. 2008, The impact of next-generation sequencing technology on genetics, Trends Genet., 24, 133-41.
    • (2008) Trends Genet. , vol.24 , pp. 133-141
    • Mardis, E.R.1
  • 12
    • 53849104257 scopus 로고    scopus 로고
    • The rational exploration of microbial diversity
    • Quince, C., Curtis, T.P. and Sloan, W.T. 2008, The rational exploration of microbial diversity, ISME J., 2, 997-1006.
    • (2008) ISME J. , vol.2 , pp. 997-1006
    • Quince, C.1    Curtis, T.P.2    Sloan, W.T.3
  • 13
    • 74049094093 scopus 로고    scopus 로고
    • The effect of sequencing errors on metagenomic gene prediction
    • Hoff, K.J. 2009, The effect of sequencing errors on metagenomic gene prediction, BMC Genomics, 10, 520.
    • (2009) BMC Genomics , vol.10 , pp. 520
    • Hoff, K.J.1
  • 14
    • 70449106047 scopus 로고    scopus 로고
    • Enabling technologies of genomicscale sequence enrichment for targeted high-throughput sequencing
    • Summerer, D. 2009, Enabling technologies of genomicscale sequence enrichment for targeted high-throughput sequencing, Genomics, 94, 363-8.
    • (2009) Genomics , vol.94 , pp. 363-368
    • Summerer, D.1
  • 15
    • 35748951614 scopus 로고    scopus 로고
    • Direct selection of human genomic loci by microarray hybridization
    • Albert, T.J., Molla, M.N., Muzny, D.M., et al. 2007, Direct selection of human genomic loci by microarray hybridization, Nat. Methods, 4, 903-5.
    • (2007) Nat. Methods , vol.4 , pp. 903-905
    • Albert, T.J.1    Molla, M.N.2    Muzny, D.M.3
  • 17
    • 77954091424 scopus 로고    scopus 로고
    • Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries
    • Mokry, M., Feitsma, H., Nijman, I.J., et al. 2010, Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries, Nucleic Acids Res., 38, e116.
    • (2010) Nucleic Acids Res. , vol.38
    • Mokry, M.1    Feitsma, H.2    Nijman, I.J.3
  • 18
    • 75349097525 scopus 로고    scopus 로고
    • Enrichment of sequencing targets from the human genome by solution hybridization
    • Tewhey, R., Nakano, M., Wang, X., et al. 2009, Enrichment of sequencing targets from the human genome by solution hybridization, Genome Biol., 10, R116.
    • (2009) Genome Biol. , vol.10
    • Tewhey, R.1    Nakano, M.2    Wang, X.3
  • 19
    • 59849113821 scopus 로고    scopus 로고
    • Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing
    • Gnirke, A., Melnikov, A., Maguire, J., et al. 2009, Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing, Nat. Biotechnol., 27, 182-9.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 182-189
    • Gnirke, A.1    Melnikov, A.2    Maguire, J.3
  • 20
    • 76349086053 scopus 로고    scopus 로고
    • Gene-targeted-metagenomics reveals extensive diversity of aromatic dioxygenase genes in the environment
    • Iwai, S., Chai, B., Sul, W.J., Cole, J.R., Hashsham, S.A. and Tiedje, J.M. 2010, Gene-targeted-metagenomics reveals extensive diversity of aromatic dioxygenase genes in the environment, ISME J., 4, 279-85.
    • (2010) ISME J. , vol.4 , pp. 279-285
    • Iwai, S.1    Chai, B.2    Sul, W.J.3    Cole, J.R.4    Hashsham, S.A.5    Tiedje, J.M.6
  • 21
    • 77956873133 scopus 로고    scopus 로고
    • Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray development
    • Terrat, S., Peyretaillade, E., Goncalves, O., et al. 2010, Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray development, BMC Bioinformatics, 11, 478.
    • (2010) BMC Bioinformatics , vol.11 , pp. 478
    • Terrat, S.1    Peyretaillade, E.2    Goncalves, O.3
  • 22
    • 83655202427 scopus 로고    scopus 로고
    • Detecting unknown sequences with DNA microarrays: Explorative probe design strategies
    • Dugat-Bony, E., Peyretaillade, E., Parisot, N., et al. 2011, Detecting unknown sequences with DNA microarrays: Explorative probe design strategies, Environ. Microbiol., 14, 356-371.
    • (2011) Environ. Microbiol. , vol.14 , pp. 356-371
    • Dugat-Bony, E.1    Peyretaillade, E.2    Parisot, N.3
  • 23
    • 0030067991 scopus 로고    scopus 로고
    • Bias caused by template annealing in the amplification of mixtures of 16S rRNA genes by PCR
    • Suzuki, M. and Giovannoni, S. 1996, Bias caused by template annealing in the amplification of mixtures of 16S rRNA genes by PCR, Appl. Environ. Microbiol., 62, 625-30.
    • (1996) Appl. Environ. Microbiol. , vol.62 , pp. 625-630
    • Suzuki, M.1    Giovannoni, S.2
  • 24
    • 72649084530 scopus 로고    scopus 로고
    • Polymerase chain reaction primers miss half of rRNA microbial diversity
    • Hong, S., Bunge, J., Leslin, C., Jeon, S. and Epstein, S.S. 2009, Polymerase chain reaction primers miss half of rRNA microbial diversity, ISME J., 3, 1365-73.
    • (2009) ISME J. , vol.3 , pp. 1365-1373
    • Hong, S.1    Bunge, J.2    Leslin, C.3    Jeon, S.4    Epstein, S.S.5
  • 25
    • 15944390886 scopus 로고    scopus 로고
    • Methane emissions from lakes: Dependence of lake characteristics, two regional assessments, and a global estimate
    • doi:10.1029/2004GB002238
    • Bastviken, D., Cole, J., Pace, M. and Tranvik, L. 2004, Methane emissions from lakes: Dependence of lake characteristics, two regional assessments, and a global estimate, Global Biogeochem. Cycles, 18, GB4009, doi:10.1029/ 2004GB002238.
    • (2004) Global Biogeochem. Cycles , vol.18
    • Bastviken, D.1    Cole, J.2    Pace, M.3    Tranvik, L.4
  • 26
    • 0033385342 scopus 로고    scopus 로고
    • Accumulation of mantle gases in a permanently stratified volcanic lake (Lake Pavin, France)
    • Aeschbach-Hertig, W., Hofer,M., Kipfer, R., Imboden, D.M. and Wieler, R., 1999, Accumulation of mantle gases in a permanently stratified volcanic lake (Lake Pavin, France), Geochim. Cosmochim. Acta, 63, 3357-72.
    • (1999) Geochim. Cosmochim. Acta , vol.63 , pp. 3357-3372
    • Aeschbach-Hertig, W.1    Hofer, M.2    Kipfer, R.3    Imboden, D.M.4    Wieler, R.5
  • 27
    • 79961168056 scopus 로고    scopus 로고
    • Identification of microbial communities involved in the methane cycle of a freshwater meromictic lake
    • Biderre-Petit, C., Jezequel, D., Dugat-Bony, E., et al. 2011, Identification of microbial communities involved in the methane cycle of a freshwater meromictic lake, FEMS Microbiol. Ecol., 77, 533-45.
    • (2011) FEMS Microbiol. Ecol. , vol.77 , pp. 533-545
    • Biderre-Petit, C.1    Jezequel, D.2    Dugat-Bony, E.3
  • 28
    • 0026732105 scopus 로고
    • Molecular biology of methanogens
    • Reeve, J.N. 1992, Molecular biology of methanogens, Annu. Rev. Microbiol., 46, 165-91.
    • (1992) Annu. Rev. Microbiol. , vol.46 , pp. 165-191
    • Reeve, J.N.1
  • 29
    • 0024058191 scopus 로고
    • Comparative analysis of genes encoding methyl coenzyme M reductase in methanogenic bacteria
    • Klein, A., Allmansberger, R., Bokranz, M., Knaub, S., Muller, B. and Muth, E. 1988, Comparative analysis of genes encoding methyl coenzyme M reductase in methanogenic bacteria, Mol. Gen. Genet., 213, 409-20.
    • (1988) Mol. Gen. Genet. , vol.213 , pp. 409-420
    • Klein, A.1    Allmansberger, R.2    Bokranz, M.3    Knaub, S.4    Muller, B.5    Muth, E.6
  • 30
    • 79951971276 scopus 로고    scopus 로고
    • HiSpOD: Probe design for functional DNA microarrays
    • Dugat-Bony, E., Missaoui, M., Peyretaillade, E., et al. 2011, HiSpOD: Probe design for functional DNA microarrays, Bioinformatics, 27, 641-8.
    • (2011) Bioinformatics , vol.27 , pp. 641-648
    • Dugat-Bony, E.1    Missaoui, M.2    Peyretaillade, E.3
  • 31
    • 52349091138 scopus 로고    scopus 로고
    • A putative new order of methanogenic Archaea inhabiting the human gut, as revealed by molecular analyses of the mcrA gene
    • Mihajlovski, A., Alric, M. and Brugere, J.F. 2008, A putative new order of methanogenic Archaea inhabiting the human gut, as revealed by molecular analyses of the mcrA gene, Res. Microbiol., 159, 516-21.
    • (2008) Res. Microbiol. , vol.159 , pp. 516-521
    • Mihajlovski, A.1    Alric, M.2    Brugere, J.F.3
  • 32
    • 0030158571 scopus 로고    scopus 로고
    • The Staden sequence analysis package
    • Staden, R. 1996, The Staden sequence analysis package, Mol. Biotechnol., 5, 233-41.
    • (1996) Mol. Biotechnol. , vol.5 , pp. 233-241
    • Staden, R.1
  • 33
    • 79952422304 scopus 로고    scopus 로고
    • Quality control and preprocessing of metagenomic datasets
    • Schmieder, R. and Edwards, R. 2011, Quality control and preprocessing of metagenomic datasets, Bioinformatics, 27, 863-4.
    • (2011) Bioinformatics , vol.27 , pp. 863-864
    • Schmieder, R.1    Edwards, R.2
  • 34
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • Altschul, S.F., Madden, T.L., Schaffer, A.A., et al. 1997, Gapped BLAST and PSI-BLAST: A new generation of protein database search programs, Nucleic Acids Res., 25, 3389-402.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3
  • 37
    • 74549125386 scopus 로고    scopus 로고
    • SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building
    • Gouy, M., Guindon, S. and Gascuel, O. 2009, SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building, Mol. Biol. Evol., 27, 221-4.
    • (2009) Mol. Biol. Evol. , vol.27 , pp. 221-224
    • Gouy, M.1    Guindon, S.2    Gascuel, O.3
  • 38
    • 33745634395 scopus 로고    scopus 로고
    • Cd-hit: A fast program for clustering and comparing large sets of protein or nucleotide sequences
    • Li, W. and Godzik, A. 2006, Cd-hit: A fast program for clustering and comparing large sets of protein or nucleotide sequences, Bioinformatics, 22, 1658-9.
    • (2006) Bioinformatics , vol.22 , pp. 1658-1659
    • Li, W.1    Godzik, A.2
  • 39
    • 0036856362 scopus 로고    scopus 로고
    • The mcrA gene as an alternative to 16S rRNA in the phylogenetic analysis of methanogen populations in landfill
    • Luton, P.E., Wayne, J.M., Sharp, R.J. and Riley, P.W. 2002, The mcrA gene as an alternative to 16S rRNA in the phylogenetic analysis of methanogen populations in landfill, Microbiology, 148, 3521-30.
    • (2002) Microbiology , vol.148 , pp. 3521-3530
    • Luton, P.E.1    Wayne, J.M.2    Sharp, R.J.3    Riley, P.W.4
  • 40
    • 0024114801 scopus 로고
    • A note on the neighbor-joining algorithm of Saitou and Nei
    • Studier, J. and Keppler, K. 1988, A note on the neighbor-joining algorithm of Saitou and Nei, Mol. Biol. Evol., 5, 729-31.
    • (1988) Mol. Biol. Evol. , vol.5 , pp. 729-731
    • Studier, J.1    Keppler, K.2
  • 41
    • 0023375195 scopus 로고
    • The neighbor-joining method: A new method for reconstructing phylogenetic trees
    • Saitou, N. and Nei, M. 1987, The neighbor-joining method: A new method for reconstructing phylogenetic trees, Mol. Biol. Evol., 4, 406-25.
    • (1987) Mol. Biol. Evol. , vol.4 , pp. 406-725
    • Saitou, N.1    Nei, M.2
  • 42
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • Tamura, K., Peterson, D., Peterson, N., Stecher, G., Nei, M. and Kumar, S. 2011, MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods, Mol. Biol. Evol., 28, 2731-9.
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 2731-9
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5    Kumar, S.6
  • 43
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak, K.J. and Schmittgen, T.D. 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method, Methods, 25, 402-8.
    • (2001) Methods , vol.25 , pp. 402-8
    • Livak, K.J.1    Schmittgen, T.D.2
  • 45
    • 33746156423 scopus 로고    scopus 로고
    • Isolation of a novel acidiphilic methanogen from an acidic peat bog
    • Brauer, S.L., Cadillo-Quiroz, H., Yashiro, E., Yavitt, J.B. and Zinder, S.H. 2006, Isolation of a novel acidiphilic methanogen from an acidic peat bog, Nature, 442, 192-4.
    • (2006) Nature , vol.442 , pp. 192-4
    • Brauer, S.L.1    Cadillo-Quiroz, H.2    Yashiro, E.3    Yavitt, J.B.4    Zinder, S.H.5
  • 46
    • 84864677092 scopus 로고    scopus 로고
    • Methanomassiliicoccus luminyensis gen. nov. sp. nov. A methanogenic archaeon isolated from human faeces
    • Dridi, B., Fardeau, M.L., Ollivier, B., Raoult, D. and Drancourt, M. 2012, Methanomassiliicoccus luminyensis gen. nov. sp. nov. a methanogenic archaeon isolated from human faeces, Int. J. Syst. Evol. Microbiol., 62, 1902-7.
    • (2012) Int. J. Syst. Evol. Microbiol. , vol.62 , pp. 1902-7
    • Dridi, B.1    Fardeau, M.L.2    Ollivier, B.3    Raoult, D.4    Drancourt, M.5
  • 47
    • 84870675165 scopus 로고    scopus 로고
    • Genome sequence of 'candidatus methanomethylophilus alvus' Mx1201, a methanogenic archaeon from the human gut belonging to a seventh order of methanogens
    • Borrel, G., Harris, H.M.B., Tottey, W., et al. 2012, Genome sequence of 'Candidatus Methanomethylophilus alvus' Mx1201, a methanogenic archaeon from the human gut belonging to a seventh order of methanogens, J. Bacteriol., 194, 6944-5.
    • (2012) J. Bacteriol. , vol.194 , pp. 6944-5
    • Borrel, G.1    Harris, H.M.B.2    Tottey, W.3
  • 48
    • 31544436089 scopus 로고    scopus 로고
    • Rapid quantitative profiling of complex microbial populations
    • Palmer, C. 2006, Rapid quantitative profiling of complex microbial populations, Nucleic Acids Res., 34, e5.
    • (2006) Nucleic Acids Res. , vol.34
    • Palmer, C.1
  • 49
    • 30744456055 scopus 로고    scopus 로고
    • The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis
    • Fricke, W.F., Seedorf, H., Henne, A., et al. 2005, The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis, J. Bacteriol., 188, 642-58.
    • (2005) J. Bacteriol. , vol.188 , pp. 642-58
    • Fricke, W.F.1    Seedorf, H.2    Henne, A.3
  • 50
    • 84863683958 scopus 로고    scopus 로고
    • Methanobacterium lacus sp. nov., a novel hydrogenotrophic methanogen from the deep cold sediment of a meromictic lake
    • Borrel, G., Joblin, K., Guedon, A., et al. 2011, Methanobacterium lacus sp. nov., a novel hydrogenotrophic methanogen from the deep cold sediment of a meromictic lake, Int. J. Syst. Evol. Microbiol., 62, 1625-1629.
    • (2011) Int. J. Syst. Evol. Microbiol. , vol.62 , pp. 1625-1629
    • Borrel, G.1    Joblin, K.2    Guedon, A.3
  • 51
    • 69749122811 scopus 로고    scopus 로고
    • Microarraybased multicycle-enrichment of genomic subsets for targeted next-generation sequencing
    • Summerer, D., Wu, H., Haase, B., et al. 2009, Microarraybased multicycle-enrichment of genomic subsets for targeted next-generation sequencing, Genome Res., 19, 1616-21.
    • (2009) Genome Res. , vol.19 , pp. 1616-21
    • Summerer, D.1    Wu, H.2    Haase, B.3
  • 52
    • 32044440730 scopus 로고    scopus 로고
    • Anaerobic microbial communities in Lake Pavin, a unique meromictic lake in France
    • Lehours, A.C., Bardot, C., Thenot, A., Debroas, D. and Fonty, G. 2005, Anaerobic microbial communities in Lake Pavin, a unique meromictic lake in France, Appl. Environ. Microbiol., 71, 7389-400.
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 7389-400
    • Lehours, A.C.1    Bardot, C.2    Thenot, A.3    Debroas, D.4    Fonty, G.5
  • 54
    • 35748938228 scopus 로고    scopus 로고
    • PhylArray: Phylogenetic probe design algorithm for microarray
    • Militon, C., Rimour, S., Missaoui, M., et al. 2007, PhylArray: Phylogenetic probe design algorithm for microarray, Bioinformatics, 23, 2550-7.
    • (2007) Bioinformatics , vol.23 , pp. 2550-7
    • Militon, C.1    Rimour, S.2    Missaoui, M.3
  • 55
    • 84870423100 scopus 로고    scopus 로고
    • KASpOD-A web service for highly specific and explorative oligonucleotide design
    • Parisot, N., Denonfoux, J., Dugat-Bony, E., Peyret, P. and Peyretaillade, E. 2012, KASpOD-a web service for highly specific and explorative oligonucleotide design, Bioinformatics, 28, 3161-3162.
    • (2012) Bioinformatics , vol.28 , pp. 3161-3162
    • Parisot, N.1    Denonfoux, J.2    Dugat-Bony, E.3    Peyret, P.4    Peyretaillade, E.5
  • 56
    • 77955463346 scopus 로고    scopus 로고
    • Third generation DNA sequencing: Pacific biosciences' single molecule real time technology
    • McCarthy, A. 2010, Third generation DNA sequencing: Pacific biosciences' single molecule real time technology, Chem. Biol., 17, 675-6.
    • (2010) Chem. Biol. , vol.17 , pp. 675-6
    • McCarthy, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.