Gap-junction-mediated communication in human periodontal ligament cells

Journal of Dental Research

Volumn 92, Issue 7, 2013, Pages 635-640

  Kato, R ^a   Ishihara, Y ^b   Kawanabe, N ^b   Sumiyoshi, K ^b   Yoshikawa, Y ^b   Nakamura, M ^b   Imai, Y ^b   Yanagita, T ^b   Fukushima, H ^b   Kamioka, H ^b   Takano Yamamoto, T ^a   Yamashiro, T ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

cell communication; Connexin43; fluorescence recovery after photobleaching; gap junctions; hypoxia; periodontal ligament

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; 18ALPHA-GLYCYRRHETINIC ACID; APLN PROTEIN, HUMAN; CALCEIN AM; CONNEXIN 43; DEFEROXAMINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; GJA1 PROTEIN, HUMAN; GLYCYRRHETINIC ACID; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SIDEROPHORE; SIGNAL PEPTIDE; TNFSF11 PROTEIN, HUMAN;

ADOLESCENT; ADULT; ARTICLE; CELL COMMUNICATION; CELL CULTURE; CELL HYPOXIA; CONFOCAL MICROSCOPY; CONNEXIN43; CULTURE TECHNIQUE; CYTOLOGY; DENDRITE; DOWN REGULATION; DRUG EFFECT; FEMALE; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GAP JUNCTION; HOMEOSTASIS; HUMAN; HYPOXIA; MALE; PERIODONTAL LIGAMENT; PHYSIOLOGY; SCANNING ELECTRON MICROSCOPY; TIME; ULTRASTRUCTURE;

CELL COMMUNICATION; CONNEXIN43; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GAP JUNCTIONS; HYPOXIA; PERIODONTAL LIGAMENT;

ADOLESCENT; ADULT; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; CELL HYPOXIA; CELLS, CULTURED; CONNEXIN 43; DEFEROXAMINE; DENDRITES; DOWN-REGULATION; FEMALE; FLUORESCEINS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENT DYES; GAP JUNCTIONS; GLYCYRRHETINIC ACID; HOMEOSTASIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; OSTEOPROTEGERIN; PERIODONTAL LIGAMENT; RANK LIGAND; SIDEROPHORES; TIME FACTORS; YOUNG ADULT;

EID: 84879165191     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034513489992     Document Type: Article

References (29)

1. Beertsen W, Everts V. Junctions between fibroblasts in mouse periodontal ligament. J Periodontal Res. 1980 ; 15: 655-668
2. Blaushild N, Michaeli Y, Steigman S. Histomorphometric study of the periodontal vasculature of the rat incisor. J Dent Res. 1992 ; 71: 1908-1912
3. Ciovacco WA, Goldberg CG, Taylor AF, Lemieux JM, Horowitz MC, Donahue HJ, et al. The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. Bone. 2009 ; 44: 80-86
4. Civitelli R. Cell-cell communication in the osteoblast/osteocyte lineage. Arch Biochem Biophys. 2008 ; 473: 188-192
5. Davidson JS, Baumgarten IM. Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. J Pharmacol Exp Ther. 1988 ; 246: 1104-1107
6. Donahue HJ. Gap junctions and biophysical regulation of bone cell differentiation. Bone. 2000 ; 26: 417-422
7. Flagg-Newton J, Simpson I, Loewenstein WR. Permeability of the cell-to-cell membrane channels in mammalian cell junction. Science. 1979 ; 205: 404-407
8. Gaengler P, Merte K. Effects of force application on periodontal blood circulation. A vital microscopic study in rats. J Periodontal Res. 1983 ; 18: 86-92
9. Ishihara Y, Kamioka H, Honjo T, Ueda H, Takano-Yamamoto T, Yamashiro T. Hormonal, pH, and calcium regulation of connexin 43-mediated dye transfer in osteocytes in chick calvaria. J Bone Miner Res. 2008 ; 23: 350-360
10. Ishihara Y, Sugawara Y, Kamioka H, Kawanabe N, Hayano S, Balam TA, et al. Ex vivo real-time observation of Ca(2+) signaling in living bone in response to shear stress applied on the bone surface. Bone. 2013 ; 53: 204-215
11. Kamioka H, Ishihara Y, Ris H, Murshid SA, Sugawara Y, Takano-Yamamoto T. Primary cultures of chick osteocytes retain functional gap junctions between osteocytes and between osteocytes and osteoblasts. Microsc Microanal. 2007 ; 13: 108-117
12. Kawanabe N, Murata S, Murakami K, Ishihara Y, Hayano S, Kurosaka H, et al. Isolation of multipotent stem cells in human periodontal ligament using stage-specific embryonic antigen-4. Differentiation. 2010 ; 79: 74-83
13. Khouw FE, Goldhaber P. Changes in vasculature of the periodontium associated with tooth movement in the rhesus monkey and dog. Arch Oral Biol. 1970 ; 15: 1125-1132
14. Kondo S, Kubota S, Shimo T, Nishida T, Yosimichi G, Eguchi T, et al. Connective tissue growth factor increased by hypoxia initiate angiogenesis in collaboration with matrix metalloproteinases. Carcinogenesis. 2002 ; 23: 769-776
15. Kubota S, Kawata K, Yanagita T, Doi H, Kitoh T, Takigawa M. Abundant retention and release of connective tissue growth factor (CTGF/CCN2) by platelets. J Biochem. 2004 ; 136: 279-282
16. Kuitert RB, van de, Velde JP, Hoeksma JB, Prahl-Andersen B. Tissue changes in the rabbit periodontal ligament during orthodontic tooth movement. Acta Morphol Neerl Scand. 1988 ; 26: 191-206
17. Li Z, Zhou Z, Yellowley CE, Donahue HJ. Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells. Bone. 1999 ; 25: 661-666
18. Matsumoto T, Iimura T, Ogura K, Moriyama K, Yamaguchi A. The role of osteocytes in bone resorption during orthodontic tooth movement. J Dent Res. 2013 ; 92: 340-345
19. Musil LS, Cunningham BA, Edelman GM, Goodenough DA. Differential phosphorylation of gap junction protein connexin 43 in junctional communication-competent and -deficient cell lines. J Cell Biol. 1990 ; 111: 2077-2088
20. Packman H, Shoher I, Stein RS. Vascular responses in the human periodontal ligament and alveolar bone detected by photoelectric plethysmography: the effect of force application to the tooth. J Periodontol. 2007 ; 48: 194-200
21. Ronkainen VP, Ronkainen JJ, Hänninen SL, Leskinen H, Ruas JL, Pereira T, et al. Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB J. 2007 ; 21: 1821-1830
22. Seo BM, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J, et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet. 2004 ; 364: 149-155
23. Sims MR, Leppard PI, Sampson WJ, Dreyer CW. Microvascular luminal volume changes in aged mouse periodontal ligament. J Dent Res. 1996 ; 75: 1503-1511
24. Su M, Borke JL, Donahue HJ, Li Z, Warshawsky NM, Russell CM, et al. Expression of connexin 43 in rat mandibular bone and periodontal ligament (PDL) cells during experimental tooth movement. J Dent Res. 1997 ; 76: 1357-1366
25. Sugawara Y, Ando R, Kamioka H, Ishihara Y, Murshid SA, Hashimoto K, et al. The alteration of a mechanical property of bone cells during the process of changing from osteoblasts to osteocytes. Bone. 2008 ; 43: 19-24
26. Takano-Yamamoto T, Takemura T, Kitamura Y, Nomura S. Site-specific expression of mRNAs for osteonectin, osteocalcin, and osteopontin revealed by in situ hybridization in rat periodontal ligament during physiological tooth movement. J Histochem Cytochem. 1994 ; 42: 885-896
27. Wang GL, Semenza GL. Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood. 1993 ; 82: 3610-3615
28. Yamaoka Y, Sawa Y, Ebata N, Ibuki N, Yoshida S, Kawasaki T. Double expression of connexin 43 and 32 in human periodontal ligament fibroblasts. Tissue Cell. 2000 ; 32: 328-335
29. Zhao M, Xiao G, Berry JE, Franceschi RT, Reddi A, Somerman MJ. Bone morphogenetic protein 2 induces dental follicle cells to differentiate toward a cementoblast/osteoblast phenotype. J Bone Miner Res. 2002 ; 17: 1441-1451