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Volumn 8, Issue 6, 2013, Pages

CD8+ T Cell Cross-Reactivity Profiles and HIV-1 Immune Escape towards an HLA-B35-Restricted Immunodominant Nef Epitope

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA B35 ANTIGEN; LEUCINE; NEF PROTEIN; PHENYLALANINE; UNCLASSIFIED DRUG; VALINE; VALYLPROLYLLEUCYLARGINYLPROLYLMETHIONYLTHREONYLTYROSINE; VIRUS RNA;

EID: 84879162101     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066152     Document Type: Article
Times cited : (6)

References (28)
  • 1
    • 68949209789 scopus 로고    scopus 로고
    • HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins
    • Brumme ZL, John M, Carlson JM, Brumme CJ, Chan D, et al. (2009) HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins. PLoS One 4: e6687.
    • (2009) PLoS One , vol.4
    • Brumme, Z.L.1    John, M.2    Carlson, J.M.3    Brumme, C.J.4    Chan, D.5
  • 3
    • 0032171644 scopus 로고    scopus 로고
    • A very high level of crossreactivity is an essential feature of the T-cell receptor
    • Mason D, (1998) A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today 19: 395-404.
    • (1998) Immunol Today , vol.19 , pp. 395-404
    • Mason, D.1
  • 4
    • 84866419166 scopus 로고    scopus 로고
    • Why must T cells be cross-reactive?
    • Sewell AK, (2012) Why must T cells be cross-reactive? Nat Rev Immunol 12: 669-677.
    • (2012) Nat Rev Immunol , vol.12 , pp. 669-677
    • Sewell, A.K.1
  • 6
    • 19944427950 scopus 로고    scopus 로고
    • HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor
    • Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, et al. (2004) HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. J Exp Med 200: 1547-1557.
    • (2004) J Exp Med , vol.200 , pp. 1547-1557
    • Dong, T.1    Stewart-Jones, G.2    Chen, N.3    Easterbrook, P.4    Xu, X.5
  • 7
    • 77952742298 scopus 로고    scopus 로고
    • Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection
    • Kosmrlj A, Read EL, Qi Y, Allen TM, Altfeld M, et al. (2010) Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection. Nature 465: 350-354.
    • (2010) Nature , vol.465 , pp. 350-354
    • Kosmrlj, A.1    Read, E.L.2    Qi, Y.3    Allen, T.M.4    Altfeld, M.5
  • 9
    • 84862621390 scopus 로고    scopus 로고
    • TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection
    • Chen H, Ndhlovu ZM, Liu D, Porter LC, Fang JW, et al. (2012) TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection. Nat Immunol 13: 691-700.
    • (2012) Nat Immunol , vol.13 , pp. 691-700
    • Chen, H.1    Ndhlovu, Z.M.2    Liu, D.3    Porter, L.C.4    Fang, J.W.5
  • 10
    • 77954484969 scopus 로고    scopus 로고
    • Interdisciplinary analysis of HIV-specific CD8+ T cell responses against variant epitopes reveals restricted TCR promiscuity
    • Hoof I, Perez CL, Buggert M, Gustafsson RK, Nielsen M, et al. (2010) Interdisciplinary analysis of HIV-specific CD8+ T cell responses against variant epitopes reveals restricted TCR promiscuity. J Immunol 184: 5383-5391.
    • (2010) J Immunol , vol.184 , pp. 5383-5391
    • Hoof, I.1    Perez, C.L.2    Buggert, M.3    Gustafsson, R.K.4    Nielsen, M.5
  • 11
    • 84875520974 scopus 로고    scopus 로고
    • A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells
    • Ladell K, Hashimoto M, Iglesias MC, Wilmann PG, McLaren JE, et al. (2013) A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity 38: 425-436.
    • (2013) Immunity , vol.38 , pp. 425-436
    • Ladell, K.1    Hashimoto, M.2    Iglesias, M.C.3    Wilmann, P.G.4    McLaren, J.E.5
  • 12
    • 66949117887 scopus 로고    scopus 로고
    • Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral activity of HIV-specific CTL
    • Motozono C, Yanaka S, Tsumoto K, Takiguchi M, Ueno T, (2009) Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral activity of HIV-specific CTL. J Immunol 182: 5528-5536.
    • (2009) J Immunol , vol.182 , pp. 5528-5536
    • Motozono, C.1    Yanaka, S.2    Tsumoto, K.3    Takiguchi, M.4    Ueno, T.5
  • 13
    • 40449098834 scopus 로고    scopus 로고
    • CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef
    • Ueno T, Motozono C, Dohki S, Mwimanzi P, Rauch S, et al. (2008) CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef. J Immunol 180: 1107-1116.
    • (2008) J Immunol , vol.180 , pp. 1107-1116
    • Ueno, T.1    Motozono, C.2    Dohki, S.3    Mwimanzi, P.4    Rauch, S.5
  • 14
    • 0036838933 scopus 로고    scopus 로고
    • Single T cell receptor-mediated recognition of an identical HIV-derived peptide presented by multiple HLA class I molecules
    • Ueno T, Tomiyama H, Takiguchi M, (2002) Single T cell receptor-mediated recognition of an identical HIV-derived peptide presented by multiple HLA class I molecules. J Immunol 169: 4961-4969.
    • (2002) J Immunol , vol.169 , pp. 4961-4969
    • Ueno, T.1    Tomiyama, H.2    Takiguchi, M.3
  • 15
    • 6344269428 scopus 로고    scopus 로고
    • Vaccination in humans generates broad T cell cytokine responses
    • De Rosa SC, Lu FX, Yu J, Perfetto SP, Falloon J, et al. (2004) Vaccination in humans generates broad T cell cytokine responses. J Immunol 173: 5372-5380.
    • (2004) J Immunol , vol.173 , pp. 5372-5380
    • De Rosa, S.C.1    Lu, F.X.2    Yu, J.3    Perfetto, S.P.4    Falloon, J.5
  • 16
    • 33646686040 scopus 로고    scopus 로고
    • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
    • Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, et al. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107: 4781-4789.
    • (2006) Blood , vol.107 , pp. 4781-4789
    • Betts, M.R.1    Nason, M.C.2    West, S.M.3    De Rosa, S.C.4    Migueles, S.A.5
  • 17
    • 77956914881 scopus 로고    scopus 로고
    • Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition
    • Cole DK, Edwards ES, Wynn KK, Clement M, Miles JJ, et al. (2010) Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. J Immunol 185: 2600-2610.
    • (2010) J Immunol , vol.185 , pp. 2600-2610
    • Cole, D.K.1    Edwards, E.S.2    Wynn, K.K.3    Clement, M.4    Miles, J.J.5
  • 19
    • 0037087319 scopus 로고    scopus 로고
    • A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape
    • Douek DC, Betts MR, Brenchley JM, Hill BJ, Ambrozak DR, et al. (2002) A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape. J Immunol 168: 3099-3104.
    • (2002) J Immunol , vol.168 , pp. 3099-3104
    • Douek, D.C.1    Betts, M.R.2    Brenchley, J.M.3    Hill, B.J.4    Ambrozak, D.R.5
  • 20
    • 33644774481 scopus 로고    scopus 로고
    • Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire
    • Meyer-Olson D, Brady KW, Bartman MT, O'Sullivan KM, Simons BC, et al. (2006) Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire. Blood 107: 2373-2383.
    • (2006) Blood , vol.107 , pp. 2373-2383
    • Meyer-Olson, D.1    Brady, K.W.2    Bartman, M.T.3    O'Sullivan, K.M.4    Simons, B.C.5
  • 22
    • 84868229860 scopus 로고    scopus 로고
    • T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting
    • Ekeruche-Makinde J, Clement M, Cole DK, Edwards ES, Ladell K, et al. (2012) T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. J Biol Chem 287: 37269-37281.
    • (2012) J Biol Chem , vol.287 , pp. 37269-37281
    • Ekeruche-Makinde, J.1    Clement, M.2    Cole, D.K.3    Edwards, E.S.4    Ladell, K.5
  • 23
    • 84857189975 scopus 로고    scopus 로고
    • Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes
    • Bulek AM, Cole DK, Skowera A, Dolton G, Gras S, et al. (2012) Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat Immunol 13: 283-289.
    • (2012) Nat Immunol , vol.13 , pp. 283-289
    • Bulek, A.M.1    Cole, D.K.2    Skowera, A.3    Dolton, G.4    Gras, S.5
  • 24
    • 0029965954 scopus 로고    scopus 로고
    • An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501
    • Smith KJ, Reid SW, Stuart DI, McMichael AJ, Jones EY, et al. (1996) An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501. Immunity 4: 203-213.
    • (1996) Immunity , vol.4 , pp. 203-213
    • Smith, K.J.1    Reid, S.W.2    Stuart, D.I.3    McMichael, A.J.4    Jones, E.Y.5
  • 25
    • 0028878783 scopus 로고
    • Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
    • Saksela K, Cheng G, Baltimore D, (1995) Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. EMBO J 14: 484-491.
    • (1995) EMBO J , vol.14 , pp. 484-491
    • Saksela, K.1    Cheng, G.2    Baltimore, D.3
  • 26
    • 79959343221 scopus 로고    scopus 로고
    • Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages
    • Mwimanzi P, Hasan Z, Hassan R, Suzu S, Takiguchi M, et al. (2011) Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages. Retrovirology 8: 50.
    • (2011) Retrovirology , vol.8 , pp. 50
    • Mwimanzi, P.1    Hasan, Z.2    Hassan, R.3    Suzu, S.4    Takiguchi, M.5
  • 27
    • 10644239910 scopus 로고    scopus 로고
    • T cell cross-reactivity and conformational changes during TCR engagement
    • Lee JK, Stewart-Jones G, Dong T, Harlos K, Di Gleria K, et al. (2004) T cell cross-reactivity and conformational changes during TCR engagement. J Exp Med 200: 1455-1466.
    • (2004) J Exp Med , vol.200 , pp. 1455-1466
    • Lee, J.K.1    Stewart-Jones, G.2    Dong, T.3    Harlos, K.4    Di Gleria, K.5
  • 28
    • 0037223712 scopus 로고    scopus 로고
    • Proline 78 is crucial for human immunodeficiency virus type 1 Nef to down-regulate class I human leukocyte antigen
    • Yamada T, Kaji N, Odawara T, Chiba J, Iwamoto A, et al. (2003) Proline 78 is crucial for human immunodeficiency virus type 1 Nef to down-regulate class I human leukocyte antigen. J Virol 77: 1589-1594.
    • (2003) J Virol , vol.77 , pp. 1589-1594
    • Yamada, T.1    Kaji, N.2    Odawara, T.3    Chiba, J.4    Iwamoto, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.