Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion

Oncotarget

Volumn 4, Issue 4, 2013, Pages 498-499

  Radisky, Derek C ^a   Nelson, Celeste M ^b  

^a MAYO CLINIC   (United States)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; MYOSIN ADENOSINE TRIPHOSPHATASE;

BIOMECHANICS; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CANCER CELL; CANCER CELL CULTURE; CELL INTERACTION; CELL INVASION; CELL MIGRATION; CYTOKINESIS; EDITORIAL; EXPLANT; EXTRACELLULAR MATRIX; MECHANICAL STRESS; MUSCLE CONTRACTILITY; NONHUMAN; REGULATORY MECHANISM; TISSUE STRUCTURE; TUMOR INVASION; TUMOR MICROENVIRONMENT;

EID: 84879160858     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.979     Document Type: Editorial

References (8)

1. Bissell, M.J. and W.C. Hines, Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med, 2011. 17(3): p. 320-9.
2. Boghaert, E., et al., Host epithelial geometry regulates breast cancer cell invasiveness. Proc Natl Acad Sci U S A, 2012. 109(48): p. 19632-7.
3. Nguyen-Ngoc, K.V., et al., ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A, 2012. 109(39): p. E2595-604.
4. Tee, S.Y., A.R. Bausch, and P.A. Janmey, The mechanical cell. Curr Biol, 2009. 19(17): p. R745-8.
5. Yamada, K.M. and E. Cukierman, Modeling tissue morphogenesis and cancer in 3D. Cell, 2007. 130(4): p. 601-10.
6. Brownfield, D.G., et al., Patterned Collagen Fibers Orient Branching Mammary Epithelium through Distinct Signaling Modules. Curr Biol, 2013.
7. Plodinec, M., et al., The nanomechanical signature of breast cancer. Nat Nanotechnol, 2012. 7(11): p. 757-65.
8. Cichon, M.A., et al., Microenvironmental influences that drive progression from benign breast disease to invasive breast cancer. J Mammary Gland Biol Neoplasia, 2010. 15(4): p. 389-97.