Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells

Archives of Toxicology

Volumn 87, Issue 7, 2013, Pages 1245-1256

  Kanno, Sanae ^a   Hirano, Seishiro ^b   Sagi, Morihisa ^a   Chiba, Shoetsu ^a   Takeshita, Hiroshi ^a   Ikawa, Toru ^a   Ichiba, Kazue ^a   Nagai, Tomonori ^a   Takada, Meri ^a   Sakamoto, Kana ^a   Mukai, Toshiji ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

Apoptosis; Cell blebbing; Flow cytometry; Rho kinase (ROCK); Sulfide

Indexed keywords

CASPASE 3; CASPASE INHIBITOR; HYDROGEN SULFIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RHO KINASE; RHO KINASE INHIBITOR; ROCK 1 KINASE; ROCK 2 KINASE; SODIUM HYDROXYSULFIDE; SULFIDE; SULFUR DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL LEVEL; CELL MEMBRANE; CONTROLLED STUDY; CYTOTOXICITY; DISSOLUTION; ENZYME ACTIVATION; GAS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PH; PRIORITY JOURNAL; PROTEIN CLEAVAGE; T LYMPHOCYTE;

APOPTOSIS; CASPASE 3; CASPASE INHIBITORS; CELL MEMBRANE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; HYDROGEN SULFIDE; HYDROGEN-ION CONCENTRATION; JURKAT CELLS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SULFIDES; T-LYMPHOCYTES;

EID: 84879139410     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1027-3     Document Type: Article

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