Application of nilvadipine solid dispersion to tablet formulation and manufacturing using crospovidone and methylcellulose as dispersion carriers

Chemical and Pharmaceutical Bulletin

Volumn 52, Issue 2, 2004, Pages 244-247

  Hirasawa, Noriyuki ^a   Ishise, Sayoko ^a   Miyata, Hitomi ^a   Danjo, Kazumi ^b  

^a Nichi Iko Pharmaceutical Co Ltd   (Japan)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

Dissolution; Nilvadipine; Solid dispersion; Tablet

Indexed keywords

CROSPOVIDONE; DRUG CARRIER; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; NILVADIPINE; DRUG DERIVATIVE; EXCIPIENT; NIFEDIPINE; POVIDONE;

AGITATION; ARTICLE; DISPERSIBLE TABLET; DISSOLUTION; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; HARDNESS; MATERIAL COATING; PARTICLE SIZE; TABLET COMPRESSION; TABLET DISINTEGRATION; TABLET FORMULATION; TEMPERATURE DEPENDENCE; CHEMISTRY; ENTERIC COATED TABLET; SOLUBILITY;

DRUG COMPOUNDING; DRUG STABILITY; EXCIPIENTS; HARDNESS; METHYLCELLULOSE; NIFEDIPINE; PARTICLE SIZE; POVIDONE; SOLUBILITY; TABLETS, ENTERIC-COATED;

EID: 4444233011     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.52.244     Document Type: Article

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