Superantigen-induced steroid resistance depends on activation of phospholipase Cβ2

Journal of Immunology

Volumn 190, Issue 12, 2013, Pages 6589-6595

  Verhaar, Auke P ^a,b   Wildenberg, Manon E ^b   Duijvestein, Marjolijn ^b   Vos, Anne Christine W ^a   Peppelenbosch, Maikel P ^c   Löwenberg, Mark ^b   Hommes, Daniel W ^a,d   Van Den Brink, Gijs R ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOLIPASE C BETA2; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TOXIC SHOCK SYNDROME; TREATMENT RESPONSE;

ANIMALS; BLOTTING, WESTERN; DEXAMETHASONE; ENZYME ACTIVATION; FEMALE; GLUCOCORTICOIDS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICE; MICE, INBRED C57BL; PHOSPHOLIPASE C BETA; RECEPTORS, ANTIGEN, T-CELL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUPERANTIGENS; TRANSFECTION;

EID: 84879110738     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202898     Document Type: Article

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