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Volumn 27, Issue 9, 2013, Pages 1387-1395

Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection

Author keywords

Antiretroviral therapy; Biomarker; CD163 protein; Cellular immunity; Macrophages; Neuropsychological; Plasma

Indexed keywords

ANTIRETROVIRUS AGENT; CD163 ANTIGEN; VIRUS RNA;

EID: 84879092495     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32836010bd     Document Type: Article
Times cited : (219)

References (43)
  • 1
    • 79957880036 scopus 로고    scopus 로고
    • HIV persistence in the gut mucosa of HIV-infected subjects undergoing antiretroviral therapy correlates with immune activation and increased levels of LPS
    • d'Ettorre G, Paiardini M, Zaffiri L, Andreotti M, Ceccarelli G, Rizza C, et al. HIV persistence in the gut mucosa of HIV-infected subjects undergoing antiretroviral therapy correlates with immune activation and increased levels of LPS. Curr HIV Res 2011; 9:148-153.
    • (2011) Curr HIV Res , vol.9 , pp. 148-153
    • D'Ettorre, G.1    Paiardini, M.2    Zaffiri, L.3    Andreotti, M.4    Ceccarelli, G.5    Rizza, C.6
  • 2
    • 77955012984 scopus 로고    scopus 로고
    • Immune exhaustion occurs concomitantly with immune activation and decrease in regulatory T cells in viremic chronically HIV-1-infected patients
    • Sachdeva M, Fischl MA, Pahwa R, Sachdeva N, Pahwa S. Immune exhaustion occurs concomitantly with immune activation and decrease in regulatory T cells in viremic chronically HIV-1-infected patients. J Acquir Immune Defic Syndr 2010; 54:447-454.
    • (2010) J Acquir Immune Defic Syndr , vol.54 , pp. 447-454
    • Sachdeva, M.1    Fischl, M.A.2    Pahwa, R.3    Sachdeva, N.4    Pahwa, S.5
  • 3
    • 0032540418 scopus 로고    scopus 로고
    • Gastrointestinal tract as a major site of CD4R T cell depletion and viral replication in SIV infection
    • Veazey RS, DeMaria M, Chalifoux LV, Shvetz DE, Pauley DR, Knight HL, et al. Gastrointestinal tract as a major site of CD4R T cell depletion and viral replication in SIV infection. Science 1998; 280:427-431.
    • (1998) Science , vol.280 , pp. 427-431
    • Veazey, R.S.1    DeMaria, M.2    Chalifoux, L.V.3    Shvetz, D.E.4    Pauley, D.R.5    Knight, H.L.6
  • 4
    • 4644337357 scopus 로고    scopus 로고
    • Getting to the guts of HIV pathogenesis
    • Veazey RS, Lackner AA. Getting to the guts of HIV pathogenesis. J Exp Med 2004; 200:697-700.
    • (2004) J Exp Med , vol.200 , pp. 697-700
    • Veazey, R.S.1    Lackner, A.A.2
  • 5
    • 49649129676 scopus 로고    scopus 로고
    • Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients
    • Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, et al. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS One 2008; 3:e2516.
    • (2008) PLoS One , vol.3
    • Ancuta, P.1    Kamat, A.2    Kunstman, K.J.3    Kim, E.Y.4    Autissier, P.5    Wurcel, A.6
  • 6
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-1371.
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3    Asher, T.E.4    Silvestri, G.5    Rao, S.6
  • 7
    • 70449494637 scopus 로고    scopus 로고
    • The level of monocyte turnover predicts disease progression in the macaque model of AIDS
    • Hasegawa A, Liu H, Ling B, Borda JT, Alvarez X, Sugimoto C, et al. The level of monocyte turnover predicts disease progression in the macaque model of AIDS. Blood 2009; 114:2917-2925.
    • (2009) Blood , vol.114 , pp. 2917-2925
    • Hasegawa, A.1    Liu, H.2    Ling, B.3    Borda, J.T.4    Alvarez, X.5    Sugimoto, C.6
  • 8
    • 77954076151 scopus 로고    scopus 로고
    • Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma
    • Burdo TH, Soulas C, Orzechowski K, Button J, Krishnan A, Sugimoto C, et al. Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma. PLoS Pathog 2010; 6:e1000842.
    • (2010) PLoS Pathog , vol.6
    • Burdo, T.H.1    Soulas, C.2    Orzechowski, K.3    Button, J.4    Krishnan, A.5    Sugimoto, C.6
  • 9
    • 79957940339 scopus 로고    scopus 로고
    • Soluble CD163 made by monocyte/macro-phages is a novel marker of HIV activity in early and chronic infection prior to and after antiretroviral therapy
    • Burdo TH, Lentz MR, Autissier P, Krishnan A, Halpern E, Letendre S, et al. Soluble CD163 made by monocyte/macro-phages is a novel marker of HIV activity in early and chronic infection prior to and after antiretroviral therapy. J Infect Dis 2011; 204:154-163.
    • (2011) J Infect Dis , vol.204 , pp. 154-163
    • Burdo, T.H.1    Lentz, M.R.2    Autissier, P.3    Krishnan, A.4    Halpern, E.5    Letendre, S.6
  • 10
    • 80052899856 scopus 로고    scopus 로고
    • Soluble CD163, a novel marker of activated macrophages, is elevated and associated with noncalcified coronary plaque in HIV-infected patients
    • Burdo TH, Lo J, Abbara S, Wei J, DeLelys ME, Preffer F, et al. Soluble CD163, a novel marker of activated macrophages, is elevated and associated with noncalcified coronary plaque in HIV-infected patients. J Infect Dis 2011; 204:1227-1236.
    • (2011) J Infect Dis , vol.204 , pp. 1227-1236
    • Burdo, T.H.1    Lo, J.2    Abbara, S.3    Wei, J.4    DeLelys, M.E.5    Preffer, F.6
  • 13
    • 0028148736 scopus 로고
    • Increased soluble CD14 serum levels and altered CD14 expression of peripheral blood monocytes in HIV-infected patients
    • Nockher WA, Bergmann L, Scherberich JE. Increased soluble CD14 serum levels and altered CD14 expression of peripheral blood monocytes in HIV-infected patients. Clin Exp Immunol 1994; 98:369-374.
    • (1994) Clin Exp Immunol , vol.98 , pp. 369-374
    • Nockher, W.A.1    Bergmann, L.2    Scherberich, J.E.3
  • 14
    • 0032530736 scopus 로고    scopus 로고
    • Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: Correlation to disease progression and clinical events
    • Lien E, Aukrust P, Sundan A, Muller F, Froland SS, Espevik T. Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood 1998; 92:2084-2092.
    • (1998) Blood , vol.92 , pp. 2084-2092
    • Lien, E.1    Aukrust, P.2    Sundan, A.3    Muller, F.4    Froland, S.S.5    Espevik, T.6
  • 15
    • 0035884444 scopus 로고    scopus 로고
    • Plasma levels of soluble CD14 and tumor necrosis factor-alpha type II receptor correlate with cognitive dysfunction during human immunodeficiency virus type 1 infection
    • Ryan LA, Zheng J, Brester M, Bohac D, Hahn F, Anderson J, et al. Plasma levels of soluble CD14 and tumor necrosis factor-alpha type II receptor correlate with cognitive dysfunction during human immunodeficiency virus type 1 infection. J Infect Dis 2001; 184:699-706.
    • (2001) J Infect Dis , vol.184 , pp. 699-706
    • Ryan, L.A.1    Zheng, J.2    Brester, M.3    Bohac, D.4    Hahn, F.5    Anderson, J.6
  • 16
    • 80051547340 scopus 로고    scopus 로고
    • Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection
    • Lyons JL, Uno H, Ancuta P, Kamat A, Moore DJ, Singer EJ, et al. Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. J Acquir Immune Defic Syndr 2011; 57:371-379.
    • (2011) J Acquir Immune Defic Syndr , vol.57 , pp. 371-379
    • Lyons, J.L.1    Uno, H.2    Ancuta, P.3    Kamat, A.4    Moore, D.J.5    Singer, E.J.6
  • 17
    • 15144361055 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication
    • Cinque P, Vago L, Mengozzi M, Torri V, Ceresa D, Vicenzi E, et al. Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication. AIDS 1998; 12:1327-1332.
    • (1998) AIDS , vol.12 , pp. 1327-1332
    • Cinque, P.1    Vago, L.2    Mengozzi, M.3    Torri, V.4    Ceresa, D.5    Vicenzi, E.6
  • 18
    • 27344435219 scopus 로고    scopus 로고
    • Dynamics of monocyte chemoattractant protein type one (MCP-1) and HIV viral load in human cerebrospinal fluid and plasma
    • Monteiro de Almeida S, Letendre S, Zimmerman J, Lazzaretto D, McCutchan A, Ellis R. Dynamics of monocyte chemoattractant protein type one (MCP-1) and HIV viral load in human cerebrospinal fluid and plasma. J Neuroimmunol 2005; 169:144-152.
    • (2005) J Neuroimmunol , vol.169 , pp. 144-152
    • Monteiro De Almeida, S.1    Letendre, S.2    Zimmerman, J.3    Lazzaretto, D.4    McCutchan, A.5    Ellis, R.6
  • 19
    • 10444241256 scopus 로고    scopus 로고
    • Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia
    • Sevigny JJ, Albert SM, McDermott MP, McArthur JC, Sacktor N, Conant K, et al. Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia. Neurology 2004; 63:2084-2090.
    • (2004) Neurology , vol.63 , pp. 2084-2090
    • Sevigny, J.J.1    Albert, S.M.2    McDermott, M.P.3    McArthur, J.C.4    Sacktor, N.5    Conant, K.6
  • 20
    • 0030431258 scopus 로고    scopus 로고
    • Clinical markers of the presence of dementia and neuropsychological impairment in HIV infection
    • Dunbar N, Pemberton L, Perdices M, Brew BJ. Clinical markers of the presence of dementia and neuropsychological impairment in HIV infection. J Neuro AIDS 1996; 1:31-48.
    • (1996) J Neuro AIDS , vol.1 , pp. 31-48
    • Dunbar, N.1    Pemberton, L.2    Perdices, M.3    Brew, B.J.4
  • 21
    • 77953017654 scopus 로고    scopus 로고
    • Cerebrospinal fluid neopterin: An informative biomarker of central nervous system immune activation in HIV-1 infection
    • Hagberg L, Cinque P, Gisslen M, Brew BJ, Spudich S, Bestetti A, et al. Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection. AIDS Res Ther 2010; 7:15.
    • (2010) AIDS Res Ther , vol.7 , pp. 15
    • Hagberg, L.1    Cinque, P.2    Gisslen, M.3    Brew, B.J.4    Spudich, S.5    Bestetti, A.6
  • 23
    • 79952921819 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: Differences in rates, nature, and predictors
    • Heaton RK, Franklin DR, Ellis RJ, McCutchan JA, Letendre SL, Leblanc S, et al. HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol 2011; 17:3-16.
    • (2011) J Neurovirol , vol.17 , pp. 3-16
    • Heaton, R.K.1    Franklin, D.R.2    Ellis, R.J.3    McCutchan, J.A.4    Letendre, S.L.5    Leblanc, S.6
  • 28
    • 84855170693 scopus 로고    scopus 로고
    • Diagnosing symptomatic HIV-associated neurocognitive disorders: Self-report versus performance-based assessment of everyday functioning
    • Blackstone K, Moore DJ, Heaton RK, Franklin DR Jr, Woods SP, Clifford DB, et al. Diagnosing symptomatic HIV-associated neurocognitive disorders: self-report versus performance-based assessment of everyday functioning. J Int Neuropsychol Soc 2012; 18:79-88.
    • (2012) J Int Neuropsychol Soc , vol.18 , pp. 79-88
    • Blackstone, K.1    Moore, D.J.2    Heaton, R.K.3    Franklin Jr., D.R.4    Woods, S.P.5    Clifford, D.B.6
  • 29
    • 7744232486 scopus 로고    scopus 로고
    • Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy
    • McArthur JC, McDermott MP, McClernon D, St Hillaire C, Conant K, Marder K, et al. Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy. Arch Neurol 2004; 61:1687-1696.
    • (2004) Arch Neurol , vol.61 , pp. 1687-1696
    • McArthur, J.C.1    McDermott, M.P.2    McClernon, D.3    St. Hillaire, C.4    Conant, K.5    Marder, K.6
  • 30
    • 3042776914 scopus 로고    scopus 로고
    • Antiretroviral treatment alters relationship between MCP-1 and neurometabolites in HIV patients
    • Chang L, Ernst T, St Hillaire C, Conant K. Antiretroviral treatment alters relationship between MCP-1 and neurometabolites in HIV patients. Antivir Ther 2004; 9:431-440.
    • (2004) Antivir Ther , vol.9 , pp. 431-440
    • Chang, L.1    Ernst, T.2    St. Hillaire, C.3    Conant, K.4
  • 32
    • 84858650532 scopus 로고    scopus 로고
    • Failure to clear intra-monocyte HIV infection linked to persistent neuropsychological testing impairment after first-line combined antiretroviral therapy
    • Shiramizu B, Ananworanich J, Chalermchai T, Siangphoe U, Troelstrup D, Shikuma C, et al. Failure to clear intra-monocyte HIV infection linked to persistent neuropsychological testing impairment after first-line combined antiretroviral therapy. J Neurovirol 2012; 18:69-73.
    • (2012) J Neurovirol , vol.18 , pp. 69-73
    • Shiramizu, B.1    Ananworanich, J.2    Chalermchai, T.3    Siangphoe, U.4    Troelstrup, D.5    Shikuma, C.6
  • 35
    • 0032868096 scopus 로고    scopus 로고
    • Human immunodeficiency virus-associated dementia
    • McArthur JC, Sacktor N, Selnes O. Human immunodeficiency virus-associated dementia. Semin Neurol 1999; 19:129-150.
    • (1999) Semin Neurol , vol.19 , pp. 129-150
    • McArthur, J.C.1    Sacktor, N.2    Selnes, O.3
  • 36
    • 9644272621 scopus 로고    scopus 로고
    • HIV dementia: An evolving disease
    • McArthur JC. HIV dementia: an evolving disease. J Neuroimmunol 2004; 157:3-10.
    • (2004) J Neuroimmunol , vol.157 , pp. 3-10
    • McArthur, J.C.1
  • 37
    • 0037168812 scopus 로고    scopus 로고
    • Medication adherence among HIVR adults: Effects of cognitive dysfunction and regimen complexity
    • Hinkin CH, Castellon SA, Durvasula RS, Hardy DJ, Lam MN, Mason KI, et al. Medication adherence among HIVR adults: effects of cognitive dysfunction and regimen complexity. Neurology 2002; 59:1944-1950.
    • (2002) Neurology , vol.59 , pp. 1944-1950
    • Hinkin, C.H.1    Castellon, S.A.2    Durvasula, R.S.3    Hardy, D.J.4    Lam, M.N.5    Mason, K.I.6
  • 39
    • 41449090950 scopus 로고    scopus 로고
    • CD163/CD16 coexpression by circulating monocytes/macrophages in HIV: Potential biomarkers for HIV infection and AIDS progression
    • Fischer-Smith T, Tedaldi EM, Rappaport J. CD163/CD16 coexpression by circulating monocytes/macrophages in HIV: potential biomarkers for HIV infection and AIDS progression. AIDS Res Hum Retroviruses 2008; 24:417-421.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , pp. 417-421
    • Fischer-Smith, T.1    Tedaldi, E.M.2    Rappaport, J.3
  • 40
    • 18244364894 scopus 로고    scopus 로고
    • CNS invasion by CD14R/CD16R peripheral blood-derived monocytes in HIV dementia: Perivascular accumulation and reservoir of HIV infection
    • Fischer-Smith T, Croul S, Sverstiuk AE, Capini C, L'Heureux D, Regulier EG, et al. CNS invasion by CD14R/CD16R peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection. J Neurovirol 2001; 7:528-541.
    • (2001) J Neurovirol , vol.7 , pp. 528-541
    • Fischer-Smith, T.1    Croul, S.2    Sverstiuk, A.E.3    Capini, C.4    L'Heureux, D.5    Regulier, E.G.6
  • 41
    • 11844282215 scopus 로고    scopus 로고
    • Human monocyte CD163 expression inversely correlates with soluble CD163 plasma levels
    • Davis BH, Zarev PV. Human monocyte CD163 expression inversely correlates with soluble CD163 plasma levels. Cytometry B Clin Cytom 2005; 63:16-22.
    • (2005) Cytometry B Clin Cytom , vol.63 , pp. 16-22
    • Davis, B.H.1    Zarev, P.V.2
  • 42
    • 64849115312 scopus 로고    scopus 로고
    • Amount of HIV DNA in peripheral blood mononuclear cells is proportional to the severity of HIV-1-associated neurocognitive disorders
    • Shiramizu B, Williams AE, Shikuma C, Valcour V. Amount of HIV DNA in peripheral blood mononuclear cells is proportional to the severity of HIV-1-associated neurocognitive disorders. J Neuropsychiatry Clin Neurosci 2009; 21:68-74.
    • (2009) J Neuropsychiatry Clin Neurosci , vol.21 , pp. 68-74
    • Shiramizu, B.1    Williams, A.E.2    Shikuma, C.3    Valcour, V.4
  • 43
    • 84864979698 scopus 로고    scopus 로고
    • Relationship between monocyte/macrophage activation marker soluble CD163 and insulin resistance in obese and normal-weight subjects
    • Zanni MV, Burdo TH, Makimura H, Williams KC, Grinspoon SK. Relationship between monocyte/macrophage activation marker soluble CD163 and insulin resistance in obese and normal-weight subjects. Clin Endocrinol (Oxf) 2012; 77:385-390.
    • (2012) Clin Endocrinol (Oxf) , vol.77 , pp. 385-390
    • Zanni, M.V.1    Burdo, T.H.2    Makimura, H.3    Williams, K.C.4    Grinspoon, S.K.5


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