Neopterin concentrations in synovial fluid may reflect disease severity in patients with osteoarthritis

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 73, Issue 4, 2013, Pages 344-348

  Zhou, Shi Jun ^a   Sun, Zhi Xia ^a   Liu, Jun ^b  

^a WEIFANG MEDICAL UNIVERSITY   (China)

^b WEIFANG PEOPLE'S HOSPITAL   (China)

Author keywords

Biomarker; Inflammatory cytokine; Neopterin; Osteoarthritis; Severity

Indexed keywords

NEOPTERIN; AUTACOID; BIOLOGICAL MARKER; CYTOKINE;

ADULT; AGE; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG SYNOVIAL FLUID LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENDER; HUMAN; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SYNOVIAL FLUID; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX; AGED; BLOOD; CASE CONTROL STUDY; CROSS-SECTIONAL STUDY; DIAGNOSTIC IMAGING; METABOLISM; MIDDLE AGED; SEVERITY OF ILLNESS INDEX;

AGED; BIOMARKERS; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; CYTOKINES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; NEOPTERIN; OSTEOARTHRITIS, KNEE; SEVERITY OF ILLNESS INDEX; SYNOVIAL FLUID;

EID: 84879083090     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.3109/00365513.2013.783228     Document Type: Article

References (21)

1. Honsawek S, Yuktanandana P, T anavalee A, C hirathaworn C, Anomasiri W, Udomsinprasert W, Saetan N, Suantawee T, Tantavisut S. Plasma and synovial fluid connective tissue growth factor levels are correlated with disease severity in patients with knee osteoarthritis. Biomarkers 2012; 17 : 303-8.
2. Li ZG, Z hao DW, X ia CJ, W ang TN, L iu YP, Z hang Y, Wang BJ. Decreased synovial fluid omentin-1 concentrations refl ect symptomatic severity in patients with knee osteoarthritis. Scand J Clin Lab Invest 2012; 72 : 623-8.
3. Patra D, S andell LJ. R ecent advances in biomarkers in osteoarthritis. Curr Opin Rheumatol 2011; 23 : 465-70
4. Yang CZ, Z hang YY, Z heng M. S oluble lectin-like oxidized low-density lipoprotein receptor-1 levels in synovial fluid are correlated with disease severity of knee osteoarthritis. Clin Biochem 2011; 44 : 1094-6.
5. Scanzello C R, G oldring S R. The role of synovitis in osteoarthritis pathogenesis. Bone 2012; 51 : 249-57
6. Fuchs D, W eiss G, R eibnegger G, W achter H. The role of neopterin as a monitor of cellular immune activation in transplantation, infl ammatory, infectious, and malignant diseases. Crit Rev Clin Lab Sci 1992; 29 : 307-41
7. D 'a gostino LE, V entimiglia F, V erna JA, C olina A D, Aguirre Y, Arturi A, Capparelli A. Correlation between DAS-28 and neopterin as a biochemical marker of immune system activation in early rheumatoid arthritis. Autoimmunity 2013; 46 : 44-9.
8. Hagihara M, N agatsu T, O hhashi M, M iura T. C oncentrations of neopterin and biopterin in serum from patients with rheumatoid arthritis or systemic lupus erythematosus and in synovial fluid from patients with rheumatoid or osteoarthritis. Clin Chem 1990; 36 : 705-6.
9. Altman R, A sch E, B loch D, B ole G, B orenstein D, Brandt K, Christy W, Cooke TD, Greenwald R, Hochberg M, Howell D, Kaplan D, Koopman W, Longley S, Mankin H, Mcshane DJ, Medsger T, Meenan R, Mikkelsen W, Moskowitz R, Murphy W, Rothschild B, Segal M, Sokoloff L, Wolfe F. Development of criteria for the classifi cation and reporting of osteoarthritis. Classifi cation of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986; 29 : 1039-49
10. Kellgren JH, L awrence JS. R adiological assessment of osteoarthrosis. Ann Rheum Dis 1957; 16 : 494-502
11. Bellamy N, B uchanan WW, G oldsmith CH, C ampbell J, Stitt LW. Validation study of WOMAC:A health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988; 15 : 1833-40
12. Avanzas P, A rroyo-Espliguero R, C osín-Sales J, A ldama G, Pizzi C, Quiles J, Kaski JC. Markers of infl ammation and multiple complex stenoses (pancoronary plaque vulnerability) in patients with non-ST segment elevation acute coronary syndromes. Heart 2004; 90 : 847-52
13. Felson D T. C linical practice. O steoarthritis of the knee. N Engl J Med 2006; 354 : 841-8.
14. Pozgan U, C aglic D, R ozman B, N agase H, T urk V, T urk B. Expression and activity profi ling of selected cysteine cathepsins and matrix metalloproteinases in synovial fl uids from patients with rheumatoid arthritis and osteoarthritis. Biol Chem 2010; 391 : 571-9.
15. Ayral X, P ickering EH, W oodworth TG, M ackillop N, Dougados M. Synovitis:A potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis-results of a 1 year longitudinal arthroscopic study in 422 patients. Osteoarthritis Cartilage 2005; 13 : 361-7.
16. Goldring MB, O tero M. I nfl ammation in osteoarthritis. Curr Opin Rheumatol 2011; 23 : 471-8.
17. De Rosa S, C irillo P, P acileo M, P etrillo G, D 'A scoli GL, Maresca F, Ziviello F, Chiariello M. Neopterin:From forgotten biomarker to leading actor in cardiovascular pathophysiology. Curr Vasc Pharmacol 2011; 9 : 188-99
18. Maerker-Alzer G, D iemer O, S tr ümper R, R ohe M. Neopterin production in infl amed knee joints:High levels in synovial fl uids. Rheumatol Int 1986; 6 : 151-4.
19. Krause A, P rotz H, G oebel K M. C orrelation between synovial neopterin and infl ammatory activity in rheumatoid arthritis. Ann Rheum Dis 1989; 48 : 636-40
20. Weinberger A. G out, uric acid metabolism, and crystalinduced infl ammation. Curr Opin Rheumatol 1995; 7 : 359-63
21. Levinger P, C aldow MK, F eller JA, B artlett JR, B ergman NR, McKenna MJ, Cameron-Smith D, Levinger I. Association between skeletal muscle infl ammatory markers and walking pattern in people with knee osteoarthritis. Arthritis Care Res (Hoboken) 2011; 63 : 1715-21