Preoperative histological subtype classification of intraductal papillary mucinous neoplasms (IPMN) by pancreatic juice cytology with MUC stain

Annals of Surgery

Volumn 257, Issue 6, 2013, Pages 1103-1111

  Hara, Taro ^a   Ikebe, Dai ^a   Odaka, Akiko ^a   Sudo, Kentaro ^a   Nakamura, Kazuyoshi ^a   Yamamoto, Hiroshi ^a   Itami, Makiko ^a   Hirata, Tetsushi ^a   Kashimura, Junya ^b   Yamaguchi, Taketo ^a  

^a CHIBA CANCER CENTER   (Japan)

^b Mito Saiseikai General Hospital   (Japan)

Author keywords

Histological subtype; Immunohistochemistry; Intraductal papillary mucinous neoplasms (IPMN); MUC; Pancreatic juice cytology

Indexed keywords

MUCIN 1; MUCIN 2; MUCIN 5AC;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURGERY; CELL STRUCTURE; CLINICAL ARTICLE; CYTOPATHOLOGY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DYSPLASIA; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FEMALE; HISTOPATHOLOGY; HUMAN; INTRADUCTAL PAPILLARY MUCINOUS TUMOR; INVASIVE CARCINOMA; MALE; PANCREAS DUCT; PANCREAS JUICE; PHENOTYPE; PREDICTIVE VALUE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY;

ADENOCARCINOMA, MUCINOUS; AGED; CARCINOMA, PANCREATIC DUCTAL; CHI-SQUARE DISTRIBUTION; CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE; DIAGNOSTIC IMAGING; FEMALE; HUMANS; MALE; NEOPLASM GRADING; NEOPLASM INVASIVENESS; PANCREATIC JUICE; PANCREATIC NEOPLASMS; PHENOTYPE; PROGNOSIS; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY;

EID: 84879076411     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e318281b824     Document Type: Article

References (46)

1. Tanaka M, Chari S, Adsay V, et al. International consensus guidelines for management of intraductal papillary neoplasms and mucinous cystic neoplasms of the pancreas. Pancreatology. 2006;6:17-32.
2. Tanno S, Nakano Y, Nishikawa T, et al. Natural history of branch duct intraductal papillary-mucinous neoplasms of the pancreas without mural nodules: long-term follow-up results. Gut. 2008;57:339-343.
3. Belyaev O, Seelig MH, Muller CA, et al. Intraductal papillary mucinous neoplasms of the pancreas. J Clin Gastroenterol. 2008;42:284-294.
4. Nagai K, Doi R, Ito T, et al. Single-institution validation of the international consensus guidelines for treatment of branch duct intraductal papillary mucinous neoplasms of the pancreas. J Hepatobiliary Pancreat Surg. 2009;16:353-358.
5. Pelaez-Luna M, Chari ST, Smyrk TC, et al. Do consensus indications for resection in branch duct intraductal papillary mucinous neoplasm predict malignancy? A study of 147 patients. Am J Gastroenterol. 2007;102:1759-1764.
6. Tang RS, Weinberg B, Dawson DW, et al. Evaluation of the guidelines formanagement of pancreatic branch-duct intraductal papillary mucinous neoplasm. Clin Gastroenterol Hepatol. 2008;6:815-819.
7. Nara S, Onaya H, Hiraoka N, et al. Preoperative evaluation of invasive and noninvasive intraductal papillary-mucinous neoplasms of the pancreas: clinical, radiological, and pathological analysis of 123 cases. Pancreas. 2009;38:8-16.
8. Murakami Y, Uemura K, Hayashidani Y, et al. Predictive factors of malignant or invasive intraductal papillary-mucinous neoplasms of the pancreas. J Gastrointest Surg. 2007;11:338-344.
9. Woo SM, Ryu JK, Lee SH, et al. Branch duct intraductal papillary mucinous neoplasms in a retrospective series of 190 patients. Br J Surg. 2009;96:405-411.
10. Yamaguchi T, Hara T, Tsuyuguchi T, et al. Peroral pancreatoscopy in the diagnosis of mucin-producing tumors of the pancreas. Gastrointest Endosc. 2000;52:67-73.
11. Hara T, Yamaguchi T, Ishihara T, et al. Diagnosis and patient management of intraductal papillary-mucinous tumor of the pancreas by using peroral pancreatoscopy and intraductal ultrasonography. Gastroenterology. 2002;122:34-43.
12. Yamaguchi T, Shirai Y, Ishihara T, et al. Pancreatic juice cytology in the diagnosis of intraductal papillary mucinous neoplasm of the pancreas: significance of sampling by peroral pancreatoscopy. Cancer. 2005;104:2830-2836.
13. Michaels PJ, Brachtel EF, Bounds BC, et al. Intraductal papillary mucinous neoplasm of the pancreas: cytologic features predict histologic grade. Cancer. 2006;108:163-173.
14. Maire F, Couvelard A, Hammel P, et al. Intraductal papillary mucinous tumors of the pancreas: the preoperative value of cytogic and histopathologic diagnosis. Gastrointest Endosc. 2003;58:701-706.
15. Shimamoto T, Tani M, Kawai M, et al. MUC1 is a useful molecular marker for malignant intraductal papillary mucinous neoplasms in pancreatic juice obtained from endoscopic retrograde pancreatography. Pancreas. 2010;39:879-883.
16. Pitman MB, Michaels PJ, Deshpande V, et al. Cytological and cyst fluid analysis of small (< or = 3 cm) branch duct intraductal papillary mucinous neoplasms adds value to patient management decisions. Pancreatology. 2008;8:277-284.
17. Correa-Gallego C, Warshaw AL, Fernandez-del Castillo C. Fluid CEA in IPMNs: a useful test or the flip of a coin?. Am J Gastroenterol. 2009;104:796-797.
18. Pitman MB, Lewandrowski K, Shen J, et al. Pancreatic cysts: preoperative diagnosis and clinical management. Cancer Cytopathol. 2010;118:1-13.
19. Maker AV, Katabi N, Gonen M, et al. Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas. Ann Surg Oncol. 2011;18:199-206.
20. Furukawa T, Kl̈oppel G, Volkan Adsay N, et al. Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study. Virchows Arch. 2005;447:794-799.
21. Bosman FT, Carneiro F, Hruban RH, et al. WHO Classification of Tumours of the Digestive System. 4th ed. Geneva: WHO; 2010.
22. Furukawa T, Hatori T, Fujita I, et al. Prognostic relevance of morphological types of intraductal papillary mucinous neoplasms of the pancreas. Gut. 2011;60:509-516.
23. Mino-Kenudson M, Ferńandez-del Castillo C, Baba Y, et al. Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes. Gut. 2011;60:1712-1720.
24. Takasu N, Kimura W, Moriya T, et al. Intraductal papillary-mucinous neoplasms of the gastric and intestinal types may have less malignant potential than the pancreatobiliary type. Pancreas. 2010;39:604-610.
25. Yonezawa S, Horinouchi M, Osako M, et al. Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor. Pathol Int. 1999;49:45-54.
26. Yonezawa S, Higashi M, Yamada N, et al. Significance of mucin expression in pancreatobiliary neoplasms. J Hepatobiliary Pancreat Sci. 2010;17:108-124.
27. Yonezawa S, Goto M, Yamada N, et al. Expression profiles of MUC1, MUC2, and MUC4 mucins in human neoplasms and their relationship with biological behavior. Proteomics. 2008;8:3329-3341.
28. Ishida M, Egawa S, Aoki T, et al. Characteristic clinicopathological features of the types of intraductal papillary-mucinous neoplasms of the pancreas. Pancreas. 2007;35:348-352.
29. Adsay NV, Merati K, Basturk O, et al. Pathologically and biologically distinct types of epithelium in intraductal papillary mucinous neoplasms: delineation of an "intestinal" pathway of carcinogenesis in the pancreas. Am J Surg Pathol. 2004;28:839-848.
30. Horinouchi M, Nagata K, Nakamura A, et al. Expression of different glycoforms of membrane mucin (MUC1) and secretory mucin (MUC2, MUC5AC and MUC6) in pancreatic neoplasms. Acta Histochem Cytochem. 2003;36:443-453.
31. Nakamura A, Horinouchi M, Goto M, et al. New classification of pancreatic intraductal papillary-mucinous tumour by mucin expression: its relationship with potential for malignancy. J Pathol. 2002;197:201-210.
32. Hibi Y, Fukushima N, Tsuchida A, et al. Pancreatic juice cytology and subclassification of intraductal papillary mucinous neoplasms of the pancreas. Pancreas. 2007;34:197-204.
33. Basturk O, Khayyata S, Klimstra DS, et al. Preferential expression of MUC6 in oncocytic and pancreatobiliary types of intraductal papillary neoplasms highlights a pyloropancreatic pathway, distinct from the intestinal pathway, in pancreatic carcinogenesis. Am J Surg Pathol. 2010;34:364-370.
34. Ferńandez-del Castillo C, Adsay NV. Intraductal papillary mucinous neoplasms of the pancreas. Gastroenterology. 2010;139:708-713.
35. Yonezawa S, Higashi M, Yamada N, et al. Precursor lesions of pancreatic cancer. Gut Liver. 2008;2:137-154.
36. Hruban RH, Takaori K, Klimstra DS, et al. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol. 2004;28:977-987.
37. Hruban RH, Pitman MB, Klimstra DS. Tumors of pancreas. In: Siberberg SG, ed. Atlas of Tumor Pathology. 4th Series, Fascicle 6. Washington, DC: American Registry of Pathology; 2007:75-110.
38. Adsay NV, Conlon KC, Zee SY, et al. Intraductal papillary-mucinous neoplasms of the pancreas: an analysis of in situ and invasive carcinomas in 28 patients. Cancer. 2002;94:62-77.
39. Ban S, Naitoh Y, Mino-Kenudson M, et al. Intraductal papillary mucinous neoplasm (IPMN) of the pancreas: its histopathologic difference between 2 major types. Am J Surg Pathol. 2006;30:1561-1569.
40. Karasaki H, Mizukami Y, Tokusashi Y, et al. Localization of the most severely dysplastic/invasive lesions and mucin phenotypes in intraductal papillary mucinous neoplasm of the pancreas. Pancreas. 2011;40:588-594.
41. Ban S, Naitoh Y, Ogawa F, et al. Intraductal papillary mucinous neoplasm (IPMN) of the gastric-type with focal nodular growth of the arborizing papillae: a case of high-grade transformation of the gastric-type IPMN. Virchows Arch. 2006;449:112-116.
42. Hara H, Suda K, Oyama T. Cytologic study of noninvasive intraductal papillary-mucinous carcinoma of the pancreas. Acta Cytol. 2002;46:519-526.
43. Yamaguchi K, Kanemitsu S, Hatori T, et al. Pancreatic ductal adenocarcinoma derived from IPMN and pancreatic ductal adenocarcinoma concomitant with IPMN. Pancreas. 2011;40:571-580.
44. Sadakari Y, Ienaga J, Kobayashi K, et al. Cyst size indicates malignant transformation in branch duct intraductal papillary mucinous neoplasm of the pancreas without mural nodule. Pancreas. 2010;39:232-236.
45. Uehara H, Nakaizumi A, Ishikawa O, et al. Development of ductal carcinoma of the pancreas during follow-up of branch duct intraductal papillary mucinous neoplasm of the pancreas. Gut. 2008;57:1561-1565.
46. Maguchi H, Tanno S, Mizuno N, et al. Natural history of branch duct intraductal papillary mucinous neoplasms of the pancreas: a multicenter study in Japan. Pancreas. 2011;40:364-370.