Upregulation of Toll-like receptor 2 gene expression by acetylation ofAP-2 alpha in THP-1 cells, a human monocytic cell line

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 8, 2013, Pages 1594-1599

  Li, Miao ^a   Li, Xi ^a   Wang, Enhua ^a   Luo, Enjie ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Acetylation; AP 2a; Gene expression; TLR2; TSA

Indexed keywords

AP 2ALPHA; LUCIFERASE; MESSENGER RNA; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA BINDING; DNA RESPONSIVE ELEMENT; ELECTROPHORESIS; ENZYME ACTIVITY; GENE EXPRESSION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MONOCYTE; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; THP 1 CELL; UPREGULATION; WESTERN BLOTTING;

EID: 84879063419     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.05.003     Document Type: Article

References (18)

1. Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006;124:783-801.. (Pubitemid 43261452)
2. Beutler BA. TLRs and innate immunity. Blood 2009;113:1399-407..
3. Brzezi'nska-Blaszczyk E, Wierzbicki M. Mast cell toll-like receptors (TLRs). Postepy Higieny i Medycyny Doswiadczalnej 2010;64:11-21..
4. Flo TH, Halaas O, Torp S, Ryan L, Lien E, Dybdahl B, et al. Differential expression of toll-like receptor 2 in human cells. Journal of Leukocyte Biology 2001;69:474-81.. (Pubitemid 32221453)
5. Gay NJ, Gangloff M. Structure and function of toll receptors and their ligands. Annual Review of Biochemistry 2007;76:141-65..
6. Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exper-imental Cell Research 1961;25:585-621..
7. Kawai Y, Garduño L, Theodore M, Yang J, Arinze IJ. Acetylation-deacetylation of thetranscription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulatesits transcriptional activity and nucleocytoplasmic localization. The Journal ofBiological Chemistry 2011;286:7629-40..
8. Legube G, Trouche D. Regulating histone acetyltransferases and deacetylases. EMBO Reports 2003;4:944-7.. (Pubitemid 37407460)
9. Li Y, Zhao Y, Li G, Wang J, Li T, Li W, et al. Regulation of neuronal nitric oxide syn-thase exon 1f gene expression by nuclear factor-kappaB acetylation in humanneuroblastoma cells. Journal of Neurochemistry 2007;101(5):1194-204.. (Pubitemid 46718805)
10. Li M, Zhao Y, Li Y, Li C, Chen F, Mao J, et al. Upregulation of human with-no-lysine kinase-4 gene expression by GATA-1 acetylation. International Journalof Biochemistry and Cell Biology 2009;41(4):872-8 [Epub August 27, 2008]..
11. Medzhitov R, Preston-Hurlburt P, Janeway CA. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997;388:394-7.. (Pubitemid 27334820)
12. Ng HH, Bird A. DNA methylation and chromatin modification. Current Opinion inGenetics and Development 1999;9:158-63.. (Pubitemid 29158549)
13. Steinbac OC, Wolffe AP, Rupp RA. Histone deacetylase activity is required for theinduction of the MyoD muscle cell lineage in Xenopus. Biological Chemistry 2000;381(9/10):1013-6..
14. Singh SK, Wilczynska KM, Grzybowski A, Yester J, Osrah B, Bryan L, et al. The uniquetranscriptional activation domain of nuclear factor-I-x3 is critical to specificallyinduce marker gene expression in astrocytes. Journal of Biological Chemistry 2011;286:7315-26..
15. Van Lint C, Emiliani S, Verdin E. The expression of a small fraction of cellulargenes is changed in response to histone hyperacetylation. Gene Expression 1996;5:245-53..
16. Yang PM, Lin PJ, Chen CC. CD1d induction in solid tumor cells by histone deacety-lase inhibitors through inhibition of HDAC1/2 and activation of Sp1. Epigenetics 2012;7(4):390-9..
17. Zähringer U, Lindner B, Inamura S, Heine H, Alexander C. TLR2 - promiscuous or spe-cific? A critical re-evaluation of a receptor expressing apparent broad specificity. Immunobiology 2008;213:205-24..
18. Zhao W, Dai F, Bonafede A, Schafer S, Jung M, Yusuf F, et al. Histone deacetylaseinhibitor, trichostatin A, affects gene expression patterns during morphogen-esis of chicken limb buds in vivo. Cells Tissues Organs 2009;190(3):121-34, http://dx.doi.org/10.1159/000193397 [Epub January, 2009]..