Effect of the Deletion of Genes Encoding Proteins of the Extracellular Virion Form of Vaccinia Virus on Vaccine Immunogenicity and Protective Effectiveness in the Mouse Model

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Meseda, Clement A ^a   Campbell, Joseph ^a   Kumar, Arunima ^a   Garcia, Alonzo D ^a   Merchlinsky, Michael ^a   Weir, Jerry P ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALLPOX VACCINE; VACCINIA VACCINE;

A33R GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; B5R GENE; CELLULAR IMMUNITY; CONTROLLED STUDY; CP77 GENE; GENE; GENE CONSTRUCT; GENE DELETION; GENE INACTIVATION; IMMUNOGENICITY; LD 50; MALE; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; VACCINATION; VIRUS NEUTRALIZATION; VIRUS RECOMBINANT; VIRUS VIRULENCE;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CELL LINE; DISEASE MODELS, ANIMAL; GENE DELETION; MALE; MICE; RECOMBINATION, GENETIC; SMALLPOX; SMALLPOX VACCINE; VACCINATION; VACCINIA VIRUS; VIRAL ENVELOPE PROTEINS; VIRION;

MURINAE; VACCINIA VIRUS; VACCINIA VIRUS WR; VARIOLA VIRUS;

EID: 84879053959     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067984     Document Type: Article

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