Computational cloning of drug target genes of a parasitic nematode, Oesophagostomum dentatum

BMC Genetics

Volumn 14, Issue , 2013, Pages

  Romine, Nathan M ^a   Martin, Richard J ^a   Beetham, Jeffrey K ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Anthelminthic; Drug resistance; In silico sequence; Nematode; Transcriptome

Indexed keywords

BENZIMIDAZOLE;

ARTICLE; CLONING; DRUG TARGETING; GENE SEQUENCE; GENE TARGETING; GENETIC IDENTIFICATION; NEMATODE; NONHUMAN; NUCLEOTIDE SEQUENCE; OESOPHAGOSTOMUM DENTATUM;

ANIMALS; ANTINEMATODAL AGENTS; CLONING, MOLECULAR; OESOPHAGOSTOMUM; POLYMERASE CHAIN REACTION;

OESOPHAGOSTOMUM DENTATUM; SUIDAE;

EID: 84879042466     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-14-55     Document Type: Article

References (23)

1. Brooker S. Estimating the global distribution and disease burden of intestinal nematode infections: adding up the numbers-a review. Int J Parasitol 2010, 40(10):1137-1144. 10.1016/j.ijpara.2010.04.004, 3034165, 20430032.
2. Martin RJ. Modes of action of anthelmintic drugs. Vet J 1997, 154(1):11-34. 10.1016/S1090-0233(05)80005-X, 9265850.
3. Robertson AP, Buxton SK, Puttachary S, Williamson SM, Wolstenholme AJ, Neveu C, Cabaret J, Charvet CL RJM. Antinematodal drugs- modes of action and resistance: and worms will not come to Thee. Parasitic Helminths, Targets, Screens, Drugs and Vaccines 2012, 233-249. Weinheim, Germany: Wiley-Blackwell, Caffrey ER.
4. Kaminsky R, Gauvry N, Schorderet Weber S, Skripsky T, Bouvier J, Wenger A, Schroeder F, Desaules Y, Hotz R, Goebel T, et al. Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate. Parasitol Res 2008, 103(4):931-939. 10.1007/s00436-008-1080-7, 2491438, 18594861.
5. Little PR, Hodges A, Watson TG, Seed JA, Maeder SJ. Field efficacy and safety of an oral formulation of the novel combination anthelmintic, derquantel-abamectin, in sheep in New Zealand. New Zeal Vet J 2010, 58(3):121-129.
6. Geerts S, Gryseels B. Drug resistance in human helminths: current situation and lessons from livestock. Clin Microbiol Rev 2000, 13(2):207-222. 10.1128/CMR.13.2.207-222.2000, 100151, 10755998.
7. James CE, Hudson AL, Davey MW. Drug resistance mechanisms in helminths: is it survival of the fittest?. Trends Parasitol 2009, 25(7):328-335. 10.1016/j.pt.2009.04.004, 19541539.
8. Martin RJ, Robertson AP. Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57. Parasitology 2007, 134(Pt 8):1093-1104.
9. Zerbino DR, Birney E. Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res 2008, 18(5):821-829. 10.1101/gr.074492.107, 2336801, 18349386.
10. Martin JA, Wang Z. Next-generation transcriptome assembly. Nat Rev Genet 2011, 12(10):671-682. 10.1038/nrg3068, 21897427.
11. Polderman AM, Blotkamp J. Oesophagostomum infections in humans. Parasitol Today 1995, 11(12):451-456. 10.1016/0169-4758(95)80058-1, 15275382.
12. Varady M, Bjorn H, Craven J, Nansen P. In vitro characterization of lines of Oesophagostomum dentatum selected or not selected for resistance to pyrantel, levamisole and ivermectin. Int J Parasitol 1997, 27(1):77-81. 10.1016/S0020-7519(96)00159-2, 9076532.
13. Leroy S, Duperray C, Morand S. Flow cytometry for parasite nematode genome size measurement. Mol Biochem Parasitol 2003, 128(1):91-93. 10.1016/S0166-6851(03)00023-9, 12706802.
14. Mizrachi E, Hefer CA, Ranik M, Joubert F, Myburg AA. De novo assembled expressed gene catalog of a fast-growing Eucalyptus tree produced by Illumina mRNA-Seq. BMC Genomics 2010, 11:681. 10.1186/1471-2164-11-681, 3053591, 21122097.
15. Tsai IJ, Otto TD, Berriman M. Improving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps. Genome Biol 2010, 11(4):R41. 10.1186/gb-2010-11-4-r41, 2884544, 20388197.
16. Consortium CS. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 1998, 282(5396):2012-2018.
17. Boulin T, Fauvin A, Charvet CL, Cortet J, Cabaret J, Bessereau JL, Neveu C. Functional reconstitution of Haemonchus contortus acetylcholine receptors in Xenopus oocytes provides mechanistic insights into levamisole resistance. Brit J Pharmacol 2011, 164(5):1421-1432.
18. Blaxter ML, De Ley P, Garey JR, Liu LX, Scheldeman P, Vierstraete A, Vanfleteren JR, Mackey LY, Dorris M, Frisse LM, et al. A molecular evolutionary framework for the phylum Nematoda. Nature 1998, 392(6671):71-75. 10.1038/32160, 9510248.
19. Towers PR, Edwards B, Richmond JE, Sattelle DB. The Caenorhabditis elegans lev-8 gene encodes a novel type of nicotinic acetylcholine receptor alpha subunit. J Neurochem 2005, 93(1):1-9. 10.1111/j.1471-4159.2004.02951.x, 15773900.
20. Robertson AP, Bjørn HE, Martin RJ. Resistance to levamisole resolved at the single-channel level. FASEB J 1999, 13(6):749-760.
21. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990, 215:403-410.
22. Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 2009, 10(3):R25. 10.1186/gb-2009-10-3-r25, 2690996, 19261174.
23. Needleman SB, Wunsch CD. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol 1970, 48(3):443-453. 10.1016/0022-2836(70)90057-4, 5420325.