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Volumn 453, Issue 1, 2013, Pages 49-60

Lipin1 regulates PPARγ transcriptional activity

Author keywords

Co activator; Co repressor; Lipin1; Peroxisome proliferator activated receptor (PPAR)

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; ISOPROTEIN; LIPIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RECEPTOR INTERACTING PROTEIN 140; ROSIGLITAZONE; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; STEROID RECEPTOR COACTIVATOR 1; THYROID HORMONE RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84879007733     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121598     Document Type: Article
Times cited : (44)

References (21)
  • 1
    • 0028015713 scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR) γ: Adipose-predominant expression and induction early in adipocyte differentiation
    • DOI 10.1210/en.135.2.798
    • Chawla, A., Schwarz, E. J., Dimaculangan, D. D. and Lazar, M. A. (1994) Peroxisome proliferator-activated receptor (PPAR) γ: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 135, 798-800 (Pubitemid 24241266)
    • (1994) Endocrinology , vol.135 , Issue.2 , pp. 798-800
    • Chawla, A.1    Schwarz, E.J.2    Dimaculangan, D.D.3    Lazar, M.A.4
  • 2
    • 0028871780 scopus 로고
    • Transdifferentiation of myoblasts by the adipogenic transcription factors PPARγ and C/EBPα
    • Hu, E., Tontonoz, P. and Spiegelman, B. M. (1995) Transdifferentiation of myoblasts by the adipogenic transcription factors PPARγ and C/EBPα. Proc. Natl. Acad. Sci. U.S.A. 92, 9856-9860
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 9856-9860
    • Hu, E.1    Tontonoz, P.2    Spiegelman, B.M.3
  • 3
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPARγ 2, a lipid-activated transcription factor
    • Tontonoz, P., Hu, E. and Spiegelman, B. M. (1994) Stimulation of adipogenesis in fibroblasts by PPARγ 2, a lipid-activated transcription factor. Cell 79, 1147-1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 4
    • 0037326196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ coactivator 1alpha (PGC-1γ): Transcriptional coactivator and metabolic regulator
    • DOI 10.1210/er.2002-0012
    • Puigserver, P. and Spiegelman, B. M. (2003) Peroxisome proliferator-activated receptor-γ coactivator 1 alpha (PGC-1γ): transcriptional coactivator and metabolic regulator. Endocr. Rev. 24, 78-90 (Pubitemid 36223280)
    • (2003) Endocrine Reviews , vol.24 , Issue.1 , pp. 78-90
    • Puigserver, P.1    Spiegelman, B.M.2
  • 5
    • 0035851187 scopus 로고    scopus 로고
    • PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen, E. D. and Spiegelman, B. M. (2001) PPARγ: a nuclear regulator of metabolism, differentiation, and cell growth. J. Biol. Chem. 276, 37731-37734
    • (2001) J. Biol. Chem. , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 7
    • 25444445879 scopus 로고    scopus 로고
    • Genomic structure and organization of the high grade Myopia-2 locus (MYP2) critical region: Mutation screening of 9 positional candidate genes
    • Scavello, Jr, G. S., Paluru, P. C., Zhou, J., White, P. S., Rappaport, E. F. and Young, T. L. (2005) Genomic structure and organization of the high grade Myopia-2 locus (MYP2) critical region: mutation screening of 9 positional candidate genes. Mol. Vision 11, 97-110 (Pubitemid 41358303)
    • (2005) Molecular Vision , vol.11 , pp. 97-110
    • Scavello Jr., G.S.1    Paluru, P.C.2    Zhou, J.3    White, P.S.4    Rappaport, E.F.5    Young, T.L.6
  • 8
    • 37449000957 scopus 로고    scopus 로고
    • The lipin protein family: Dual roles in lipid biosynthesis and gene expression
    • Reue, K. and Zhang, P. (2008) The lipin protein family: dual roles in lipid biosynthesis and gene expression. FEBS Lett. 582, 90-96
    • (2008) FEBS Lett. , vol.582 , pp. 90-96
    • Reue, K.1    Zhang, P.2
  • 9
    • 84856292633 scopus 로고    scopus 로고
    • Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor gamma (PPARγ) gene expression during adipogenesis
    • Zhang, P., Takeuchi, K., Csaki, L. S. and Reue, K. (2012) Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor gamma (PPARγ) gene expression during adipogenesis. J. Biol. Chem. 287, 3485-3494
    • (2012) J. Biol. Chem. , vol.287 , pp. 3485-3494
    • Zhang, P.1    Takeuchi, K.2    Csaki, L.S.3    Reue, K.4
  • 10
    • 33744954152 scopus 로고    scopus 로고
    • A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation
    • DOI 10.1074/jbc.M509612200
    • Gale, S. E., Frolov, A., Han, X., Bickel, P. E., Cao, L., Bowcock, A., Schaffer, J. E. and Ory, D. S. (2006) A regulatory role for 1-acylglycerol-3- phosphate-O-acyltransferase 2 in adipocyte differentiation. J. Biol. Chem. 281, 11082-11089 (Pubitemid 43855532)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.16 , pp. 11082-11089
    • Gale, S.E.1    Frolov, A.2    Han, X.3    Bickel, P.E.4    Cao, L.5    Bowcock, A.6    Schaffer, J.E.7    Ory, D.S.8
  • 11
    • 77953522115 scopus 로고    scopus 로고
    • GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis
    • Shan, D., Li, J. L., Wu, L., Li, D., Hurov, J., Tobin, J. F., Gimeno, R. E. and Cao, J. (2010) GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis. J. Lipid Res. 51, 1971-1981
    • (2010) J. Lipid Res. , vol.51 , pp. 1971-1981
    • Shan, D.1    Li, J.L.2    Wu, L.3    Li, D.4    Hurov, J.5    Tobin, J.F.6    Gimeno, R.E.7    Cao, J.8
  • 12
    • 33747853190 scopus 로고    scopus 로고
    • Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway
    • DOI 10.1016/j.cmet.2006.08.005, PII S1550413106002750
    • Finck, B. N., Gropler, M. C., Chen, Z., Leone, T. C., Croce, M. A., Harris, T. E., Lawrence, Jr, J. C. and Kelly, D. P. (2006) Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway. Cell Metab. 4, 199-210 (Pubitemid 44283957)
    • (2006) Cell Metabolism , vol.4 , Issue.3 , pp. 199-210
    • Finck, B.N.1    Gropler, M.C.2    Chen, Z.3    Leone, T.C.4    Croce, M.A.5    Harris, T.E.6    Lawrence Jr., J.C.7    Kelly, D.P.8
  • 13
    • 70349291072 scopus 로고    scopus 로고
    • Sumoylation regulates nuclear localization of lipin-1α in neuronal cells
    • Liu, G. H. and Gerace, L. (2009) Sumoylation regulates nuclear localization of lipin-1α in neuronal cells. PLoS ONE 4, e7031
    • (2009) PLoS ONE , vol.4
    • Liu, G.H.1    Gerace, L.2
  • 14
    • 58049218441 scopus 로고    scopus 로고
    • Lipin1 is a key factor for the maturation and maintenance of adipocytes in the regulatory network with CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma 2
    • Koh, Y. K., Lee, M. Y., Kim, J. W., Kim, M., Moon, J. S., Lee, Y. J., Ahn, Y. H. and Kim, K. S. (2008) Lipin1 is a key factor for the maturation and maintenance of adipocytes in the regulatory network with CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma 2. J. Biol. Chem. 283, 34896-34906
    • (2008) J. Biol. Chem. , vol.283 , pp. 34896-34906
    • Koh, Y.K.1    Lee, M.Y.2    Kim, J.W.3    Kim, M.4    Moon, J.S.5    Lee, Y.J.6    Ahn, Y.H.7    Kim, K.S.8
  • 15
    • 77953400436 scopus 로고    scopus 로고
    • Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors
    • Kim, H. B., Kumar, A., Wang, L., Liu, G. H., Keller, S. R., Lawrence, Jr, J. C., Finck, B. N. and Harris, T. E. (2010) Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors. Mol. Cell. Biol. 30, 3126-3139
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 3126-3139
    • Kim, H.B.1    Kumar, A.2    Wang, L.3    Liu, G.H.4    Keller, S.R.5    Lawrence Jr., J.C.6    Finck, B.N.7    Harris, T.E.8
  • 16
    • 21244480972 scopus 로고    scopus 로고
    • The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth
    • DOI 10.1038/sj.emboj.7600672
    • Santos-Rosa, H., Leung, J., Grimsey, N., Peak-Chew, S. and Siniossoglou, S. (2005) The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth. EMBO J. 24, 1931-1941 (Pubitemid 40896165)
    • (2005) EMBO Journal , vol.24 , Issue.11 , pp. 1931-1941
    • Santos-Rosa, H.1    Leung, J.2    Grimsey, N.3    Peak-Chew, S.4    Siniossoglou, S.5
  • 17
    • 25444465996 scopus 로고    scopus 로고
    • Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis
    • DOI 10.1074/jbc.M503885200
    • Peterfy, M., Phan, J. and Reue, K. (2005) Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis. J. Biol. Chem. 280, 32883-32889 (Pubitemid 41368337)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.38 , pp. 32883-32889
    • Peterfy, M.1    Phan, J.2    Reue, K.3
  • 18
    • 70350399460 scopus 로고    scopus 로고
    • A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2
    • Donkor, J., Zhang, P., Wong, S., O'Loughlin, L., Dewald, J., Kok, B. P., Brindley, D. N. and Reue, K. (2009) A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2. J. Biol. Chem. 284, 29968-29978
    • (2009) J. Biol. Chem. , vol.284 , pp. 29968-29978
    • Donkor, J.1    Zhang, P.2    Wong, S.3    O'Loughlin, L.4    Dewald, J.5    Kok, B.P.6    Brindley, D.N.7    Reue, K.8
  • 19
    • 17144395146 scopus 로고    scopus 로고
    • The nuclear receptor corepressors NCoR and SMRT decrease peroxisome proliferator-activated receptor γ transcriptional activity and repress 3T3-L1 adipogenesis
    • DOI 10.1074/jbc.M409468200
    • Yu, C., Markan, K., Temple, K. A., Deplewski, D., Brady, M. J. and Cohen, R. N. (2005) The nuclear receptor corepressors NCoR and SMRT decrease peroxisome proliferator-activated receptor γ transcriptional activity and repress 3T3-L1 adipogenesis. J. Biol. Chem. 280, 13600-13605 (Pubitemid 40517253)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.14 , pp. 13600-13605
    • Yu, C.1    Markan, K.2    Temple, K.A.3    Deplewski, D.4    Brady, M.J.5    Cohen, R.N.6
  • 20
    • 4143099405 scopus 로고    scopus 로고
    • Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes
    • DOI 10.1074/jbc.M405346200
    • Tzameli, I., Fang, H., Ollero, M., Shi, H., Hamm, J. K., Kievit, P., Hollenberg, A. N. and Flier, J. S. (2004) Regulated production of a peroxisome proliferator-activated receptor-γ ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes. J. Biol. Chem. 279, 36093-36102 (Pubitemid 39100617)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.34 , pp. 36093-36102
    • Tzameli, I.1    Fang, H.2    Ollero, M.3    Shi, H.4    Hamm, J.K.5    Kievit, P.6    Hollenberg, A.N.7    Flier, J.S.8
  • 21
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
    • DOI 10.1016/S0092-8674(00)81574-3
    • Nagy, L., Tontonoz, P., Alvarez, J. G., Chen, H. and Evans, R. M. (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 93, 229-240 (Pubitemid 28180856)
    • (1998) Cell , vol.93 , Issue.2 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.A.3    Chen, H.4    Evans, R.M.5


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