Toxicity and endocrine disruption in zebrafish (Danio rerio) and two freshwater invertebrates (Daphnia magna and Moina macrocopa) after chronic exposure to mefenamic acid

Ecotoxicology and Environmental Safety

Volumn 94, Issue , 2013, Pages 80-86

  Jung Collard, Hyo rin ^a,b   Ji, Kyunghee ^a,c   Lee, Sangwoo ^a   Liu, Xiaoshan ^a   Kang, Sungeun ^a   Kho, Younglim ^d   Ahn, Byeongwoo ^e   Ryu, Jisung ^f   Lee, Jaean ^f   Choi, Kyungho ^a  

^a Seoul National University   (South Korea)

^b CHA University   (South Korea)

^c Yongin University   (South Korea)

^d Eulji University   (South Korea)

^e Chungbuk National University   (South Korea)

^f National Institute of Environmental Research   (South Korea)

Author keywords

Cyp19a; NSAIDs; Steroidogenic pathway; Vitellogenin; Waterflea

Indexed keywords

AROMATASE; GONADORELIN; GONADORELIN RECEPTOR; MEFENAMIC ACID; VITELLOGENIN;

CONCENTRATION (COMPOSITION); DRUG; ECOTOXICOLOGY; ENDOCRINE DISRUPTOR; FISH; GENE EXPRESSION; HISTOLOGY; INVERTEBRATE; RNA; TOXICITY; TOXICITY TEST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC TOXICITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYP19A GENE; CYP19B GENE; DAPHNIA MAGNA; ECOTOXICITY; ENDOCRINE DISEASE; FEMALE; FRESHWATER SPECIES; GENE; GENE EXPRESSION REGULATION; GNRH GENE; GNRHR GENE; HISTOPATHOLOGY; HYPOTHALAMUS HYPOPHYSIS SYSTEM; LONG TERM EXPOSURE; MALE; MOINA MACROCOPA; NONHUMAN; NUCLEOTIDE SEQUENCE; REPRODUCTIVE TOXICITY; SURVIVAL RATE; UPREGULATION; ZEBRA FISH;

ANIMALS; CLADOCERA; DAPHNIA; ENDOCRINE DISRUPTORS; ENDOCRINE SYSTEM; FRESH WATER; LARVA; MALE; MEFENAMIC ACID; REPRODUCTION; RNA, MESSENGER; TOXICITY TESTS, CHRONIC; VITELLOGENINS; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO; DAPHNIA MAGNA; INVERTEBRATA; MOINA MACROCOPA; TELEOSTEI;

EID: 84879006834     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2013.04.027     Document Type: Article

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