메뉴 건너뛰기




Volumn 54, Issue 6, 2013, Pages 3985-3998

A systematic review on zinc for the prevention and treatment of age-related macular degeneration

Author keywords

Age related macular degeneration; Systematic review; Zinc

Indexed keywords

PLACEBO; UNCLASSIFIED DRUG; ZINC ION; ZINC MONOCYSTEINE; ZINC OXIDE; ZINC SULFATE;

EID: 84878982146     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-11552     Document Type: Review
Times cited : (67)

References (34)
  • 1
    • 0033497453 scopus 로고    scopus 로고
    • Age-related maculopathy in a multiracial United States population: The National Health and Nutrition Examination Survey III
    • Klein R, Klein BE, Jensen SC, Mares-Perlman JA, Cruickshanks KJ, Palta M. Age-related maculopathy in a multiracial United States population: the National Health and Nutrition Examination Survey III. Ophthalmology. 1999;106:1056-1065.
    • (1999) Ophthalmology , vol.106 , pp. 1056-1065
    • Klein, R.1    Klein, B.E.2    Jensen, S.C.3    Mares-Perlman, J.A.4    Cruickshanks, K.J.5    Palta, M.6
  • 2
    • 84878998502 scopus 로고    scopus 로고
    • Prevalence of Blindness Data Tables (NEI Statistics and Data). National Eye Institute, National Institutes of Health, Available at, Accessed June 7, 2012
    • Prevalence of Blindness Data Tables (NEI Statistics and Data). National Eye Institute, National Institutes of Health. 2004. Available at: http://www.nei.nih.gov/eyedata/. Accessed June 7, 2012.
    • (2004)
  • 4
    • 0028879019 scopus 로고
    • Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins
    • Snodderly DM. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr. 1995;62:1448S-1461S.
    • (1995) Am J Clin Nutr , vol.62
    • Snodderly, D.M.1
  • 5
    • 0034063877 scopus 로고    scopus 로고
    • Role of zinc in plasma membrane function
    • O'Dell BL. Role of zinc in plasma membrane function. J Nutr. 2000;130:1432S-1436S.
    • (2000) J Nutr , vol.130
    • O'Dell, B.L.1
  • 6
    • 84878998260 scopus 로고    scopus 로고
    • Food and Nutrition Board. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press
    • Food and Nutrition Board. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press; 2001.
    • (2001)
  • 7
    • 0031789295 scopus 로고    scopus 로고
    • Zinc deficiency in humans: A neglected problem
    • Prasad AS. Zinc deficiency in humans: a neglected problem. J Am Coll Nutr. 1998;17:542-543.
    • (1998) J Am Coll Nutr , vol.17 , pp. 542-543
    • Prasad, A.S.1
  • 9
    • 46149097697 scopus 로고    scopus 로고
    • Zinc
    • Bowen BA, Russell, RM, ed., 9th ed, Washington, DC: ILSI Press
    • Cousins RJ. Zinc. In: Bowen BA, Russell, RM, ed. Present Knowledge in Nutrition. 9th ed. Vol. 1. Washington, DC: ILSI Press; 2006;445-457.
    • (2006) Present Knowledge In Nutrition , vol.1 , pp. 445-457
    • Cousins, R.J.1
  • 10
    • 84859001212 scopus 로고    scopus 로고
    • The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
    • Higgins JPT, Altman DG, Gotzsche PC, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.
    • (2011) BMJ , vol.343
    • Higgins, J.P.T.1    Altman, D.G.2    Gotzsche, P.C.3
  • 11
    • 68549101842 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration
    • Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009;339:b2700.
    • (2009) BMJ , vol.339
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3
  • 13
    • 0032527738 scopus 로고    scopus 로고
    • Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculop-athy in the Beaver Dam Eye Study
    • VandenLangenberg GM, Mares-Perlman JA, Klein R, Klein BEK, Brady WE, Palta M. Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculop-athy in the Beaver Dam Eye Study. Am J Epidemiol. 1998;148: 204-214.
    • (1998) Am J Epidemiol , vol.148 , pp. 204-214
    • Vandenlangenberg, G.M.1    Mares-Perlman, J.A.2    Klein, R.3    Klein, B.E.K.4    Brady, W.E.5    Palta, M.6
  • 14
    • 0034980123 scopus 로고    scopus 로고
    • Prospective study of zinc intake and the risk of age-related macular degeneration
    • Cho E, Stampfer MJ, Seddon JM, et al. Prospective study of zinc intake and the risk of age-related macular degeneration. Ann Epidemiol. 2001;11:328-336.
    • (2001) Ann Epidemiol , vol.11 , pp. 328-336
    • Cho, E.1    Stampfer, M.J.2    Seddon, J.M.3
  • 15
    • 29544441148 scopus 로고    scopus 로고
    • Dietary intake of antioxidants and risk of age-related macular degeneration
    • van Leeuwen R, Boekhoorn S, Vingerling JR, et al. Dietary intake of antioxidants and risk of age-related macular degeneration. JAMA. 2005;294:3101-3107.
    • (2005) JAMA , vol.294 , pp. 3101-3107
    • van Leeuwen, R.1    Boekhoorn, S.2    Vingerling, J.R.3
  • 16
    • 38749097003 scopus 로고    scopus 로고
    • Dietary antioxidants and the long-term incidence of agerelated macular degeneration: The Blue Mountains Eye Study
    • Tan JSL, Wang JJ, Flood V, Rochtchina E, Smith W, Mitchell P. Dietary antioxidants and the long-term incidence of agerelated macular degeneration: the Blue Mountains Eye Study. Ophthalmology. 2008;115:334-341.
    • (2008) Ophthalmology , vol.115 , pp. 334-341
    • Tan, J.S.L.1    Wang, J.J.2    Flood, V.3    Rochtchina, E.4    Smith, W.5    Mitchell, P.6
  • 17
    • 0029778163 scopus 로고    scopus 로고
    • Association of zinc and antioxidant nutrients with age-related maculopathy
    • Mares-Perlman JA, Klein R, Klein BEK, et al. Association of zinc and antioxidant nutrients with age-related maculopathy. Arch Ophthalmol. 1996;114:991-997.
    • (1996) Arch Ophthalmol , vol.114 , pp. 991-997
    • Mares-Perlman, J.A.1    Klein, R.2    Klein, B.E.K.3
  • 18
    • 36249031619 scopus 로고    scopus 로고
    • Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions
    • Morris MS, Jacques PF, Chylack LT, et al. Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions. Ophthalmic Epidemiol. 2007;14:288-298.
    • (2007) Ophthalmic Epidemiol , vol.14 , pp. 288-298
    • Morris, M.S.1    Jacques, P.F.2    Chylack, L.T.3
  • 20
  • 21
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta-carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
    • Age-related Eye Disease Study Research Group
    • Age-related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta-carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001;119:1417-1436.
    • (2001) Arch Ophthalmol , vol.119 , pp. 1417-1436
  • 22
    • 46749115130 scopus 로고    scopus 로고
    • Prospective, placebo-controlled clinical trial of a novel zinc-monocysteine compound in age-related macular degeneration
    • Newsome DA, Randomized, A. Prospective, placebo-controlled clinical trial of a novel zinc-monocysteine compound in age-related macular degeneration. Curr Eye Res. 2008;33: 591-598.
    • (2008) Curr Eye Res , vol.33 , pp. 591-598
    • Newsome, D.A.1    Randomized, A.2
  • 23
    • 70349255600 scopus 로고    scopus 로고
    • Change in area of geographic atrophy in the Age-Related Eye Disease Study: AREDS report number 26
    • Lindblad A, Lloyd P, Clemons T, et al. Change in area of geographic atrophy in the Age-Related Eye Disease Study: AREDS report number 26. Arch Ophthalmol. 2009;127:1168.
    • (2009) Arch Ophthalmol , vol.127 , pp. 1168
    • Lindblad, A.1    Lloyd, P.2    Clemons, T.3
  • 24
    • 77954759614 scopus 로고    scopus 로고
    • Novel method for analyzing Snellen visual acuity measurements
    • Gregori NZ, Feuer W, Rosenfeld PJ. Novel method for analyzing Snellen visual acuity measurements. Retina. 2010; 30:1046-1050.
    • (2010) Retina , vol.30 , pp. 1046-1050
    • Gregori, N.Z.1    Feuer, W.2    Rosenfeld, P.J.3
  • 25
    • 35348966298 scopus 로고    scopus 로고
    • Dietary antioxidants and primary prevention of age related macular degeneration: Systematic review and meta-analysis
    • Chong EWT, Wong TY, Kreis AJ, Simpson JA, Guymer RH. Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis. BMJ. 2007;335:755.
    • (2007) BMJ , vol.335 , pp. 755
    • Chong, E.W.T.1    Wong, T.Y.2    Kreis, A.J.3    Simpson, J.A.4    Guymer, R.H.5
  • 26
    • 45449118333 scopus 로고    scopus 로고
    • Antioxidant supplements to prevent or slow down the progression of AMD: A systematic review and meta-analysis
    • Evans J. Antioxidant supplements to prevent or slow down the progression of AMD: a systematic review and meta-analysis. Eye (Lond). 2008;22:751-760.
    • (2008) Eye (Lond) , vol.22 , pp. 751-760
    • Evans, J.1
  • 27
    • 0031041935 scopus 로고    scopus 로고
    • Reproducibility of visual acuity measurements in patients with retinitis pigmentosa
    • Grover S, Fishman GA, Gilbert LD, Anderson RJ. Reproducibility of visual acuity measurements in patients with retinitis pigmentosa. Retina. 1997;17:33-37.
    • (1997) Retina , vol.17 , pp. 33-37
    • Grover, S.1    Fishman, G.A.2    Gilbert, L.D.3    Anderson, R.J.4
  • 28
    • 33750347637 scopus 로고    scopus 로고
    • Implantable miniature telescope for the treatment of visual acuity loss resulting from end-stage age-related macular degeneration: 1-year results
    • Hudson HL, Lane SS, Heier JS, et al. Implantable miniature telescope for the treatment of visual acuity loss resulting from end-stage age-related macular degeneration: 1-year results. Ophthalmology. 2006;113:1987-2001.
    • (2006) Ophthalmology , vol.113 , pp. 1987-2001
    • Hudson, H.L.1    Lane, S.S.2    Heier, J.S.3
  • 29
    • 0034109890 scopus 로고    scopus 로고
    • The Age- Related Eye Disease Study: A clinical trial of zinc and antioxidants-Age-Related Eye Disease Study Report No. 2
    • Age-Related Eye Disease Study Research Group
    • Age-Related Eye Disease Study Research Group. The Age- Related Eye Disease Study: a clinical trial of zinc and antioxidants-Age-Related Eye Disease Study Report No. 2. J Nutr. 2000;130:1516S-1519S.
    • (2000) J Nutr , vol.130
  • 31
    • 40649098105 scopus 로고    scopus 로고
    • Food and Nutrition Board, Institute of Medicine, National Academies, Available at, Accessed December 12, 2012
    • Food and Nutrition Board, Institute of Medicine, National Academies. Dietary reference intakes (DRIs): recommended dietary allowances and adequate intakes, vitamins. Available at: http://iom.edu/Activities/Nutrition/SummaryDRIs/~/media/ Files/Activity%20Files/Nutrition/DRIs/RDA%20and%20AIs_Vitamin%20and%20Elements.pdf. Accessed December 12, 2012.
    • Dietary Reference Intakes (DRIs): Recommended Dietary Allowances and Adequate Intakes, Vitamins
  • 32
    • 0038455700 scopus 로고    scopus 로고
    • Registering clinical trials
    • Dickersin K, Rennie D. Registering clinical trials. JAMA. 2003; 290:516-523.
    • (2003) JAMA , vol.290 , pp. 516-523
    • Dickersin, K.1    Rennie, D.2
  • 33
    • 29444458752 scopus 로고    scopus 로고
    • The pharmacokinetics of zinc from zinc gluconate: A comparison with zinc oxide in healthy men
    • Siepmann M, Spank S, Kluge A, Schappach A, Kirch W. The pharmacokinetics of zinc from zinc gluconate: a comparison with zinc oxide in healthy men. Int J Clin Pharmacol Ther. 2005;43:562-565.
    • (2005) Int J Clin Pharmacol Ther , vol.43 , pp. 562-565
    • Siepmann, M.1    Spank, S.2    Kluge, A.3    Schappach, A.4    Kirch, W.5
  • 34
    • 84878983302 scopus 로고    scopus 로고
    • Age-Related Eye Disease Study. AREDS 2. Available at, Accessed June 10
    • Age-Related Eye Disease Study. AREDS 2. Available at: www.areds2.org. Accessed June 10, 2011.
    • (2011)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.