Schizophrenia and visual backward masking: A general deficit of target enhancement

Frontiers in Psychology

Volumn 4, Issue MAY, 2013, Pages

  Herzog, Michael H ^a   Roinishvili, Maya ^b,c   Chkonia, Eka ^c,d   Brand, Andreas ^e  

^a EPFL   (Switzerland)

^b Georgia   (Georgia)

^c AGRICULTURAL UNIVERSITY OF GEORGIA   (Georgia)

^d TBILISI STATE MEDICAL UNIVERSITY   (Georgia)

^e KLINIKUM BREMEN OST   (Germany)

Author keywords

Acetylcholine receptor; Attention; Schizophrenia; Vernier acuity; Vision

Indexed keywords

EID: 84878969632     PISSN: None     EISSN: 16641078     Source Type: Journal    
DOI: 10.3389/fpsyg.2013.00254     Document Type: Article

References (71)

1. Adler, L. E., Cawthra, E. M., Donovan, K. A., Harris, J. G., Nagamoto, H. T., Olincy, A., et al. (2005). Improved p50 auditory gating with ondansetron in medicated schizophrenia patients. Am. J. Psychiatry 162, 386-388.
2. Adler, L. E., Olincy, A., Waldo, M., Harris, J. G., Griffith, J., Stevens, K., et al. (1998). Schizophrenia, sensory gating, and nicotinic receptors. Schizophr. Bull. 24, 189-202.
3. Adler, L. E., Waldo, M. C., Tatcher, A., Cawthra, E., Baker, N., and Freedman, R. (1991). Lack of relationship of auditory gating defects to negative symptoms in schizophrenia. Schizophr. Res. 3, 131-138.
4. Bakanidze, G., Puls, I., Brand, A., Herzog, M. H., Roinishvili, M., and Chkonia, E. (2009). The influence of genetic variants of the CHRNA7 gene on backward masking in schizophrenic patients. Eur. Arch. Psychiatry. Clin. Neurosci. 259(Suppl. 1), S101.
5. Bentley, P., Driver, J., and Dolan, R. J. (2011). Cholinergic modulation of cognition: insights from human pharmacological functional neuroimaging. Prog. Neurobiol. 94, 360-388.
6. Bleuler, E. (1911). Dementia praecox oder Gruppe der Schizophrenien. Leipzig; Wien: F. Deuticke.
7. Braff, D. L. (1981). Impaired speed of information processing in nonmedicated schizotypal patients. Schizophr. Bull. 7, 499-508.
8. Braff, D. L., and Saccuzzo, D. P. (1981). Information processing dysfunction in paranoid schizophrenia: a two-factor deficit. Am. J. Psychiatry 138, 1051-1056.
9. Breitmeyer, B. G., and Ganz, L. (1976). Implications of sustained and transient channels for theories of visual pattern masking, saccadic suppression, and information processing. Psychol. Rev. 83, 1-36.
10. Butler, P. D., Martinez, A., Foxe, J. J., Kim, D., Zemon, V., Silipo, G., et al. (2007). Subcortical visual dysfunction in schizophrenia drives secondary cortical impairments. Brain 130, 417-430.
11. Cadenhead, K. S., Geyer, M. A., Butler, R. W., Perry, W., Sprock, J., and Bradd, D. L. (1997). Information processing deficits of schizophrenia patients: relationship to clinical ratings, gender and medication status. Schizophr. Res. 28, 51-62.
12. Calderone, D. J., Martinez, A., Zemon, V., Hoptman, M. J., Hu, G., Watkins, J. E., et al. (2013). Comparison of psychophysical, electrophysiological, and fMRI assessment of visual contrast responses in patients with schizophrenia. Neuroimage 67, 153-162.
13. Cappe, C., Herzog, M. H., Herzig, D. A., Brand, A., and Mohr, C. (2012). Cognitive disorganisation in schizotypy is associated with deterioration in visual backward masking. Psychiatry Res. 200, 652-659.
14. Chkonia, E., Roinishvili, M., Makhatadze, N., Tsverava, L., Stroux, A., Neumann, K., et al. (2010). The shine-through masking paradigm is a potential endophenotype of schizophrenia. PLoS ONE 5:e14268. doi: 10.1371/journal.pone.0014268
15. Chkonia, E., Roinishvili, M., Reichard, L., Wurch, W., Puhlmann, H., Grimsen, C., et al. (2012). Patients with functional psychoses show similar visual backward masking deficits. Psychiatry Res. 198, 235-240.
16. Cornblatt, B. A., and Keilp, J. G. (1994). Impaired attention, genetics, and the pathophysiology of schizophrenia. Schizophr. Bull. 20, 31-46.
17. Cullum, C. M., Harris, J. G., Waldo, M. C., Smernoff, E., Madison, A., Nagamoto, H. T., et al. (1993). Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia. Schizophr. Res. 10, 131-141.
18. Deco, G., and Thiele, A. (2009). Attention: oscillations and neuropharmacology. Eur. J. Neurosci. 30, 347-354.
19. Delord, S., Ducato, M. G., Pins, D., Devinck, F., Thomas, P., Boucart, M., et al. (2006). Psychophysical assessment of magno- and parvocellular function in schizophrenia. Vis. Neurosci. 23, 645-650.
20. Dickerson, F., Stallings, C. R., Origoni, A. E., Vaughan, C., Khushalani, S., Schroeder, J., et al. (2013). Cigarette smoking among persons with schizophrenia or bipolar disorder in routine clinical settings, 1999-2011. Psychiatr. Serv. 64, 44-50.
21. Disney, A. A., Aoki, C., and Hawken, M. J. (2007). Gain modulation by nicotine in macaque V1. Neuron 56, 701-713.
22. Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urteger, A., Olincy, A., Davis, A, et al. (1997). Linkages of a neurophysiological deficit in schizophrenia to chromosome 15 locus. Proc. Natl. Acad. Sci. U.S.A. 94, 587-592.
23. Gallowitsch-Puerta, M., and Tracey, K. J. (2005). Immunologic role of the cholinergic anti-inflammatory pathway and the nicotinic acetylcholine α7 receptor. Ann. N.Y. Acad. Sci. 1062, 1-11.
24. Gil, Z., Connors, B. W., and Amitai, Y. (1997). Differential regulation of neocortical synapses by neuromodulators and activity. Neuron 19, 679-686.
25. Green, M. F. (2006). Cognitive impairment and functional outcome in schizophrenia and bipolar disorder. J. Clin. Psychiatry 67, 3-8. discussion: 36-42.
26. Green, M. F., Nuechterlein, K. H., and Mintz, J. (1994a). Backward masking in schizophrenia and mania. I. Specifying a mechanism. Arch. Gen. Psychiatry 51, 939-944.
27. Green, M. F., Nuechterlein, K. H., and Mintz, J. (1994b). Backward masking in schizophrenia and mania. II. Specifying the visual channels. Arch. Gen. Psychiatry 51, 945-951.
28. Herzog, M. H., Ernst, U., Etzold, A., and Eurich, C. (2003). Local interactions in neural networks explain global effects in Gestalt processing and masking. Neural Comput. 15, 2091-2113.
29. Herzog, M. H., and Fahle, M. (2002). Effects of grouping in contextual modulation. Nature 415, 433-436.
30. Herzog, M. H., and Koch, C. (2001). Seeing properties of an invisible object: feature inheritance and shine-through. Proc. Natl. Acad. Sci. U.S.A. 98, 4271-4275.
31. Herzog, M. H., Kopmann, S., and Brand, A. (2004). Intact figure-ground segmentation in schizophrenia. Psychiatry Res. 129, 55-63.
32. Hillyard, S. A., and Anllo-Vento, L. (1998). Event-related brain potentials in the study of visual selective attention. Proc. Natl. Acad. Sci. U.S.A. 95, 781-787.
33. Holzer, L., Jaugey, L., Chinet, L., and Herzog, M. H. (2009). Deteriorated visual backward masking in the shine-through effect in adolescents with psychosis. J. Clin. Exp. Neuropsychol. 31, 641-647.
34. Houy, E., Raux, G., Thibaut, F., Belmont, A., Demily, C., Allio, G., et al. (2004). The promoter -194 C polymorphism of the nicotinic alpha 7 receptor gene has a protective effect against the P50 sensory gating deficit. Mol. Psychiatry 9, 320-322.
35. Kéri, S., Kelemen, O., Benedek, G., and Janka, Z. (2004). Vernier threshold in patients with schizophrenia and in their unaffected siblings. Neuropsychology 18, 537-542.
36. Knott, V., Shah, D., Millar, A., McIntosh, J., Fisher, D., Blais, C., et al. (2012). Nicotine, auditory sensory memory, and sustained attention in a human ketamine model of schizophrenia: moderating influence of a hallucinatory trait. Front. Pharmacol. 3:172. doi: 10.3389/fphar.2012.00172
37. Martin, L. F., Leonard, S., Hall, M. H., Tregellas, J. R., Freedman, R., and Olincy, A. (2007). Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B, 611-614.
38. Maunsell, J. H. R., and Cook, E. P. (2002). The role of attention in visual processing. Philos. Trans. R. Soc. Lond. B Biol. Sci. 357, 1063-1072.
39. Messamore, E. (2012). Niacin subsensitivity is associated with functional impairment in schizophrenia. Schizophr. Res. 137, 180-184.
40. Moran, L. V., Sampath, H., Kochunov, P., and Hong, L. E. (2012). Brain circuits that link schizophrenia to high risk of cigarette smoking. Schizophr. Bull. doi: 10.1093/schbul/sbs149. [Epub ahead of print].
41. Nelson, C. L., Sarter, M., and Bruno, J. P. (2005). Prefrontal cortical modulation of acetylcholine release in posterior parietal cortex. Neuroscience 132, 347-359.
42. Nestor, P. G., and O'Donnell, B. F. (1998). "The mind adrift: attentional dysregulation in schizophrenia," in The Attentive Brain, ed R. Parasuraman (Cambridge, MA: MIT Press), 527-546.
43. Nuechterlein, K. H., Dawson, M. E., Gitlin, M., Ventura, J., Goldstein, M. J., Snyder, K. S., et al. (1992). Developmental processes in schizophrenic disorders: longitudinal studies of vulnerability and stress. Schizophr. Bull. 18, 387-425.
44. Olincy, A., Braff, D. L., Adler, L. E., Cadenhead, K. S., Calkins, M. E., Dobie, D. J., et al. (2010). Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophr. Res. 119, 175-182.
45. Olincy, A., and Freedman, R. (2012). Nicotinic mechanisms in the treatment of psychotic disorders: a focus on the α7 nicotinic receptor. Handb. Exp. Pharmacol. 213, 211-232.
46. Origlia, N., Valenzano, D. R., Moretti, M., Gotti, C., and Domenici, L. (2012). Visual acuity is reduced in lpha 7 nicotinic receptor knockout mice. Invest. Ophthalmol. Vis. Sci. 53, 1211-1218.
47. Parasuraman, R., and Greenwood, P. (2004). "Molecular genetics of visuospatial attention and working memory," in Cognitive Neuroscience of Attention, ed M. I. Posner (New York; London: Guilford Press), 245-259.
48. Plomp, G., Roinishvili, M., Chkonia, E., Kapanadze, G., Kereselidze, M., Brand, A., et al. (2013). Electrophysiological evidence for ventral stream deficits in schizophrenia patients. Schizophr. Bull. 39, 547-554.
49. Posner, M. I., and Petersen, S. E. (1990). The attention system of the human brain. Annu. Rev. Neurosci. 13, 25-42.
50. Puri, B. K., Easton, T., Das, I., Kidane, L., and Richardson, A. J. (2001). The niacin skin flush test in schizophrenia: a replication study. Int. J. Clin. Pract. 55, 368-370.
51. Raux, G., Bonnet-Brilhault, F., Louchart, S., Houy, E., Gantier, R., Levillain, D., et al. (2002). The -2 bp deletion in exon 6 of the 'alpha 7-like' nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit. Mol. Psychiatry 7, 1006-1011.
52. Reynolds, J. H., and Heeger, D. J. (2009). The normalization model of attention. Neuron 61, 68-185.
53. Roinishvili, M., Chkonia, E., Brand, A., and Herzog, M. H. (2008). Contextual suppression and protection in schizophrenic patients. Eur. Arch. Psychiatry Clin. Neurosci. 258, 210-216.
54. Rund, B. R., Øie, M., and Sundet, K. (1996). Backward-masking deficit in adolescents with schizophrenic disorders or attention deficit hyperactivity disorder. Am. J. Psychiatry 153, 1154-1157.
55. Saccuzzo, D. P., and Braff, D. L. (1981). Early information processing deficit in schizophrenia. New findings using schizophrenic subgroups and manic control subjects. Arch. Gen. Psychiatry 38, 175-179.
56. Saccuzzo, D. P., Hirt, M., and Spencer, T. J. (1974). Backward masking as a measure of attention in schizophrenia. J. Abnorm. Psychol. 83, 512-522.
57. Saccuzzo, D. P., and Schubert, D. L. (1981). Backward masking as a measure of slow processing in schizophrenia spectrum disorders. J. Abnorm. Psychol. 90, 305-312.
58. Sarter, M., Lustig, C., and Taylor, S. F. (2012). Cholinergic contributions to the cognitive symptoms of schizophrenia and the viability of cholinergic treatments. Neuropharmacology 62, 1544-1553.
59. Sarter, M., Parikh, V., and Howe, W. M. (2009). Phasic acetylcholine release and the volume transmission hypothesis: time to move on. Nat. Rev. Neurosci. 10, 383-390.
60. Schechter, I., Butler, P. D., Silipo, G., Zemon, V., and Javitt, D. C. (2003). Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia. Schizophr. Res. 64, 91-101.
61. Schuck, J. R., and Lee, R. G. (1989). Backward masking, information processing, and schizophrenia. Schizophr. Bull. 15, 491-500.
62. Schütze, C., Bongard, I., Marbach, S., Brand, A., and Herzog, M. H. (2007). Collinear contextual suppression in schizophrenic patients. Psychiatry Res. 150, 237-243.
63. Schwartz, B. D., Winstead, D. K., and Adinoff, B. (1983). Temporal integration deficit in visual information processing by chronic schizophrenics. Biol. Psychiatry 18, 1311-1320.
64. Skottun, B. C., and Skoyles, J. R. (2007). Contrast sensitivity and magnocellular functioning in schizophrenia. Vision Res. 47, 2923-2933.
65. Skottun, B. C., and Skoyles, J. R. (2009). Are masking abnormalities in schizophrenia limited to backward masking? Int. J. Neurosci. 119, 88-104.
66. Slaghuis, W. L. (1998). Contrast sensitivity for stationary and drifting spatial frequency ggratings in positive- and negative-symptom schizophrenia. J. Abnorm. Psychol. 107, 49-62.
67. Slaghuis, W. L. (2004). Spatio-temporal luminance contrast sensitivity and visual backward masking in schizophrenia. Exp. Brain Res. 156, 196-211.
68. Treue, S., and Martínez-Trujillo, J. C. (1999). Feature-based attention influences motion processing gain in macaque visual cortex. Nature 399, 575-579.
69. Treue, S., and Maunsell, J. H. (1996). Attentional modulation of visual motion processing in cortical areas MT and MST. Nature 382, 539-541.
70. Yakel, J. L. (2013). Cholinergic receptors: functional role of nicotinic ACh receptors in brain circuits and disease. Pflugers Arch. 465, 441-450.
71. Zhang, X. Y., Liu, L., Liu, S., Hong, X., Chen da, C., Xiu, M. H., et al. (2012). Short-term tropisetron treatment and cognitive and p50 auditory gating deficits in schizophrenia. Am. J. Psychiatry 169, 974-981.