Variations of dietary salt and fluid modulate calcium and magnesium transport in the renal distal tubule

Nephron - Physiology

Volumn 122, Issue 3-4, 2013, Pages 19-27

  Lee, Chien Te ^a   Lien, Yeong Hau H ^b,d   Lai, Li Wen ^c   Ng, Hwee Yeong ^a   Chiou, Terry Ting Yu ^a   Chen, Hung Chun ^b  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c UNIVERSITY OF ARIZONA   (United States)

^d Arizona Kidney Disease and Hypertension Center   (United States)

Author keywords

Calcium transport; Fluid; Magnesium transport; Salt; TRPM6; TRPV5; TRPV6

Indexed keywords

CALBINDIN; CALCIUM; MAGNESIUM; PARATHYROID HORMONE; PROTEIN KINASE WNK1; PROTEIN KINASE WNK4; TRANSIENT RECEPTOR POTENTIAL CHANNEL M6; VANILLOID RECEPTOR 5; VANILLOID RECEPTOR 6;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CALCIUM TRANSPORT; CONTROLLED STUDY; DEHYDRATION; FLUID BALANCE; FLUID INTAKE; GENE EXPRESSION; GENETIC ANALYSIS; HIGH SODIUM INTAKE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; KIDNEY DISTAL TUBULE; MAGNESIUM EXCRETION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SALT INTAKE; SODIUM RESTRICTION; SODIUM URINE LEVEL; URINALYSIS; URINARY EXCRETION; URINE VOLUME;

ANIMALS; CALBINDIN 1; CALCIUM; CALCIUM CHANNELS; DRINKING; GENE EXPRESSION REGULATION; KIDNEY TUBULES, DISTAL; MAGNESIUM; MALE; PARATHYROID HORMONE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM CHLORIDE, DIETARY; TRPM CATION CHANNELS; TRPV CATION CHANNELS;

EID: 84878940438     PISSN: None     EISSN: 16602137     Source Type: Journal    
DOI: 10.1159/000353199     Document Type: Article

References (26)

1. Knepper MA, Brooks HL: Regulation of the sodium transporters NHE3, NKCC2 and NCC in the kidney. Curr Opin Nephrol Hypertens 2001; 10: 655-659.
2. Schrier RW: Body water homeostasis: clinical disorders of urinary dilution and concentration. J Am Soc Nephrol 2006; 17: 1820-1832.
3. Biner HL, Arpin-Bott MP, Loffing J, Wang X, Knepper M, Hebert SC, Kaissling B: Human cortical distal nephron: distribution of electrolyte and water transport pathways. J Am Soc Nephrol 2002; 13: 836-847.
4. van de Graaf SF, Bindels RJ, Hoenderop JG: Physiology of epithelial Ca 2+ and Mg 2+ transport. Rev Physiol Biochem Pharmacol 2007; 158: 77-160.
5. Hoenderop JGJ, Bindels RJM: Epithelial Ca 2+ and Mg 2+ channels in health and disease. J Am Soc Nephrol 2005; 16: 15-26.
6. Hoorn EJ, Nelson JH, McCormick JA, Ellison DH: The WNK kinase network regulating sodium, potassium and blood pressure. J Am Soc Nephrol 2011; 22: 605-614.
7. Jiang Y, Ferguson WB, Peng JB: WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4. Am J Physiol Renal Physiol 2007; 292:F545-F554.
8. Zhang W, Na T, Peng JB: WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway. Am J Physiol Renal Physiol 2008; 295:F1472-F1484.
9. Massey LK, Whiting SJ: Dietary salt, urinary calcium, and bone loss. J Bone Miner Res 1996; 11: 731-736.
10. Hills AG, Parsons DW, Webster GD Jr, Rosenthal O, Conover H: Influence of the renal excretion of sodium chloride upon the renal excretion of magnesium and other ions by human subjects. J Clin Endocrinol Metab 1959; 19: 1192-1211.
11. Nijenhuis T, Hoenderop JG, Loffing J, van der Kemp AW, van Os CH, Bindels RJ: Thiazideinduced hypocalciuria is accompanied by a decreased expression of Ca 2+ transport proteins in kidney. Kidney Int 2003; 64: 555-564.
12. Heo NJ, Kim HS, Lee JH, Jang HR, Kim SJ, Oh YK, Na KY, Joo KW, Han JS: Expression of calcium transporters according to dietary sodium in the distal tubule of rat kidneys. Korean J Nephrol 2007; 26: 390-397.
13. Moreno G, Merino A, Mercado A, Herrera JP, Gonzalez-Salazar J, Correa-Rotter R, Hebert SC, Gamba G: Electroneutral Na-coupled cotransporter expression in the kidney during variations of NaCl and water metabolism. Hypertension 1998; 31: 1002-1006.
14. Lee CT, Lien YH, Lai LW, Chen JB, Lin CR, Chen HC: Increased renal calcium and magnesium transporter abundance in streptozotocin- induced diabetes mellitus. Kidney Int 2006; 69: 1786-1791.
15. Chan EL, Ho CS, MacDonald D, Ho SC, Chan TY, Swaminathan R: Interrelationships between urinary sodium, calcium, hydroxyproline and serum PTH in healthy subjects. Acta Endocrinol (Copenh) 1992; 127: 242-245.
16. Friedman PA: Codependence of renal calcium and sodium transport. Annu Rev Physiol 1998; 60: 179-197.
17. Loffing J, Kaissling B: Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human. Am J Physiol Renal Physiol 2003; 84:F628-F643.
18. Lee CT, Chen HC, Lien YH, Lai LW: Effects of furosemide on renal distal tubule calcium handling. Am J Physiol Renal Physiol 2007; 293:F1231-F1237.
19. van Abel M, Hoenderop JG, van der Kemp AW, Friedlaender MM, van Leeuwen JP, Bindels RJ: Coordinated control of renal Ca 2+ transport proteins by parathyroid hormone. Kidney Int 2005; 68: 1708-1721.
20. Nijenhuis T, Renkema KY, Hoenderop JG, Bindels RJ: Acid-base status determines the renal expression of Ca 2+ and Mg 2+ transport proteins. J Am Soc Nephrol 2006; 17: 617-626.
21. O'Reilly M, Marshall E, MacGillivray T, Mittal M, Xue W, Kenyon CJ, Brown RW: Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo . J Am Soc Nephrol 2006; 17: 2402-2413.
22. Chiga M, Rai T, Yang SS, Ohta A, Takizawa T, Sasaki S, Uchida S: Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone. Kidney Int 2008; 74: 1403-1409.
23. Masilamani S, Wang X, Kim GH, Brooks H, Nielsen J, Nielsen S, Nakamura K, Stokes JB, Knepper MA: Time course of renal Na-KATPase, NHE3, NKCC2, NCC, and ENaC abundance changes with dietary NaCl restriction. Am J Physiol Renal Physiol 2002; 283:F648-F657.
24. Dimke H: Exploring the intricate regulatory network controlling the thiazide-sensitive NaCl cotransporter (NCC). Pflugers Arch 2011; 462: 767-777.
25. Blanchard A, Jeunemaitre X, Coudol P, Dechaux M, Froissart M, May A, Demontis R, Fournier A, Paillard M, Houillier P: Paracellin- 1 is critical for magnesium and calcium reabsorption in the human thick ascending limb of Henle. Kidney Int 2001; 59: 2206-2215.
26. Groenestege WM, Hoenderop JG, van den Heuvel L, Knoers N, Bindels RJ: The epithelial Mg 2+ channel transient receptor potential melastatin 6 is regulated by dietary Mg 2+ content and estrogens. J Am Soc Nephrol 2006; 17: 1035-1043.