Stress-Induced Visceral Hypersensitivity in Maternally Separated Rats Can Be Reversed by Peripherally Restricted Histamine-1-Receptor Antagonists

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Stanisor, Oana I ^a   van Diest, Sophie A ^a   Yu, Zhumei ^a,b   Welting, Olaf ^a   Bekkali, Noor ^a   Shi, Jing ^b   de Jonge, Wouter J ^a   Boeckxstaens, Guy E ^c   van den Wijngaard, Rene M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; CAREBASTINE; CELL PROTEIN; EBASTINE; FEXOFENADINE; HISTAMINE H1 RECEPTOR; OCCLUDIN; PROTEIN RMCP 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON DILATATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG MEGADOSE; DRUG SAFETY; ENZYME RELEASE; HYPERSENSITIVITY; IN VITRO STUDY; IN VIVO STUDY; MAST CELL DEGRANULATION; MATERNAL DEPRIVATION; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRESS; VASCULAR RESISTANCE; VISCERAL HYPERSENSITIVITY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BUTYROPHENONES; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE H1 ANTAGONISTS; IRRITABLE BOWEL SYNDROME; MAST CELLS; MATERNAL DEPRIVATION; OCCLUDIN; PIPERIDINES; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRESS, PSYCHOLOGICAL; TERFENADINE;

RATTUS;

EID: 84878910661     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066884     Document Type: Article

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