Engineering, conjugation, and immunogenicity assessment of Escherichia coli O121 O antigen for its potential use as a typhoid vaccine component

Glycoconjugate Journal

Volumn 30, Issue 5, 2013, Pages 511-522

  Wetter, Michael ^a   Kowarik, Michael ^a   Steffen, Michael ^a   Carranza, Paula ^a   Corradin, Giampietro ^b   Wacker, Michael ^a  

^a GlycoVaxyn AG   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Conjugate vaccine; Escherichia coli O121; O antigen; Salmonella Typhi; Vi antigen

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL POLYSACCHARIDE; EPITOPE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN; O ANTIGEN; TYPHOID VACCINE; UNCLASSIFIED DRUG; VI ANTIGEN;

ANIMAL EXPERIMENT; ANTIBODY TITER; ANTIGEN STRUCTURE; ARTICLE; BACTERIAL GENE; CARBOHYDRATE ANALYSIS; CONJUGATION; CONTROLLED STUDY; CROSS REACTION; DRUG SYNTHESIS; ESCHERICHIA COLI; ESCHERICHIA COLI O121; FEMALE; GENE INACTIVATION; IMMUNIZATION; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; SEROCONVERSION; WBQG GENE;

ANIMALS; ANTIBODIES, BACTERIAL; CAMPYLOBACTER JEJUNI; CARBOHYDRATE SEQUENCE; ESCHERICHIA COLI; FEMALE; GLYCOCONJUGATES; GLYCOSYLATION; HEXOSYLTRANSFERASES; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; O ANTIGENS; POLYSACCHARIDES, BACTERIAL; PROTEIN ENGINEERING; SALMONELLA TYPHI; TYPHOID FEVER; TYPHOID-PARATYPHOID VACCINES; VACCINES, CONJUGATE;

ANIMALIA; BACTERIA (MICROORGANISMS); CAMPYLOBACTER JEJUNI; ESCHERICHIA COLI; MUS; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHI; SALMONELLA TYPHI;

EID: 84878884180     PISSN: 02820080     EISSN: 15734986     Source Type: Journal    
DOI: 10.1007/s10719-012-9451-9     Document Type: Article

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