N-glycan analysis of human α1-antitrypsin produced in Chinese hamster ovary cells

Glycoconjugate Journal

Volumn 30, Issue 5, 2013, Pages 537-547

  Lee, Kyung Jin ^a,e   Lee, Sang Mee ^b   Gil, Jin Young ^a,c   Kwon, Ohsuk ^a   Kim, Jin Young ^d   Park, Soon Jae ^b   Chung, Hye Shin ^b,c   Oh, Doo Byoung ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Alteogen Inc   (South Korea)

^c Hannam University   (South Korea)

^d Korea Basic Science Institute (KBSI)   (South Korea)

^e Wonkwang University   (South Korea)

Author keywords

Alpha1 antitrypsin; Antennary structure; Chinese hamster ovary (CHO) cells; In vivo half life; N glycan; Sialic acid

Indexed keywords

ALPHA 1 ANTITRYPSIN; FUCOSE; GLYCAN; RECOMBINANT PROTEIN; SIALIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOHYDRATE ANALYSIS; CHO CELL; CONTROLLED STUDY; DEGLYCOSYLATION; DRUG BLOOD LEVEL; DRUG HALF LIFE; ENZYME INHIBITION; IN VIVO STUDY; MALE; MOLECULAR SIZE; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; RAT; SIALYLATION; SINGLE DRUG DOSE;

ALPHA 1-ANTITRYPSIN; ANIMALS; CARBOHYDRATE SEQUENCE; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETULUS; ENZYME ASSAYS; GLYCOSYLATION; HALF-LIFE; HUMANS; KINETICS; LEUKOCYTE ELASTASE; MOLECULAR SEQUENCE DATA; POLYSACCHARIDES; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SWINE;

CRICETULUS GRISEUS; RATTUS; TETRA;

EID: 84878864924     PISSN: 02820080     EISSN: 15734986     Source Type: Journal    
DOI: 10.1007/s10719-012-9453-7     Document Type: Article

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