Repeat oral dose toxicity studies of melamine in rats and monkeys

Archives of Toxicology

Volumn 87, Issue 3, 2013, Pages 517-527

  Early, Richard J ^a   Yu, Hong ^a   Mu, Xueyan Peter ^a   Xu, Haiyan ^a   Guo, Lei ^a   Kong, Qingxue ^a   Zhou, Junma ^a   He, Bruce ^a   Yang, Xiuying ^a   Huang, Hailiang ^b   Hu, Edward ^a   Jiang, Ying ^a  

^a WUXI APPTEC   (China)

^b Johns Hopkins University   (United States)

Author keywords

Biomarker; Melamine; Nephrotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; CLUSTERIN; CREATININE; CYSTATIN C; MELAMINE; NITROGEN; OSTEOPONTIN; UREA;

A2M GENE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CD44 GENE; CLUSTERIN GENE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYSTATIN C GENE; DOWN REGULATION; FEMALE; GENE; GENE EXPRESSION REGULATION; GENETIC MARKER; GPNMB GENE; HAPLORHINI; HEMATOPOIESIS; KIDNEY INJURY; KIDNEY TUBULE EPITHELIUM; KIM 1 GENE; LCN2 GENE; MALE; MORTALITY; NEPHROTOXICITY; NONHUMAN; ORGAN WEIGHT; PERICARDITIS; PRIORITY JOURNAL; RAT; SPP1 GENE; TCFRSF12A GENE; TOXICITY TESTING; TREFOIL FACTOR 3 GENE; TURBIDITY; UPREGULATION; UREA NITROGEN BLOOD LEVEL; URINE COLOR; WEIGHT REDUCTION;

ADMINISTRATION, ORAL; ANIMAL FEED; ANIMALS; BIOLOGICAL MARKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOOD CONTAMINATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC MARKERS; KIDNEY; KIDNEY DISEASES; MACACA FASCICULARIS; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RATS; RATS, SPRAGUE-DAWLEY; RISK ASSESSMENT; TIME FACTORS; TOXICITY TESTS; TRIAZINES;

ANIMALIA; RATTUS;

EID: 84878858544     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0939-7     Document Type: Article

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