Reduced Lantadenes A and B: Semi-synthetic synthesis, selective cytotoxicity, apoptosis induction and inhibition of NO, TNF-α production in HL-60 cells

Medicinal Chemistry Research

Volumn 22, Issue 7, 2013, Pages 3379-3388

  Kumar, Suthar Sharad ^a   Tailor, Navin ^a   Lee, Hong Boon ^b   Sharma, Manu ^a  

^a JAYPEE UNIVERSITY OF INFORMATION TECHNOLOGY   (India)

^b Drug Discovery Laboratory   (Malaysia)

Author keywords

Apoptosis; Cytotoxicity; NO; Reduced Lantadenes A and B; TNF ; Transcription factors

Indexed keywords

22 BETA [(3 METHYL 1 OXO 2 BUTENYL) OXY] 3 BETA HYDROXYOLEAN 12 EN 28 OIC ACID; ANTINEOPLASTIC AGENT; CASPASE 3; CISPLATIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LANTADENES A; LANTADENES B; MESSENGER RNA; NITRIC OXIDE; NITRITE; PROTEIN BAX; PROTEIN BCL 2; TRANSCRIPTION FACTOR; TRITERPENOID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CELL CYCLE REGULATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; LANTANA CAMARA; LEUKEMIA; MICROWAVE IRRADIATION; PROTEIN EXPRESSION; STIMULATION; WEED;

EID: 84878828653     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0354-x     Document Type: Article

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