Healing of fresh frozen bone allograft with or without platelet-rich plasma: A histologic and histometric study in rats

Clinical Implant Dentistry and Related Research

Volumn 15, Issue 3, 2013, Pages 438-447

  Messora, Michel ^a   Braga, Laís ^a   Oliveira, Gabriela ^a   Oliveira, Luiz Fernando ^a   Milagres, Roselaine ^a   Kawata, Leandro ^a   Furlaneto, Flávia ^b   Pola, Natália ^c   Campos, Natália ^c   Nagata, Maria ^c  

^a Lavras University Center UNILAVRAS   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Bone regeneration; Homologous; Platelet rich plasma; Transplantation

Indexed keywords

COLLAGEN;

ALLOGRAFT; ANIMAL; ARTICLE; AUTOGRAFT; BLOOD CLOTTING; BONE DEVELOPMENT; BONE DISEASE; BONE TRANSPLANTATION; COMPARATIVE STUDY; CRYOPRESERVATION; FIBROBLAST; IMAGE PROCESSING; MALE; METHODOLOGY; OSTEOBLAST; OSTEOCYTE; PATHOLOGY; PHYSIOLOGY; RANDOMIZATION; RAT; SKULL; THROMBOCYTE RICH PLASMA; TRANSPLANTATION; WISTAR RAT; WOUND HEALING;

ALLOGRAFTS; ANIMALS; AUTOGRAFTS; BLOOD COAGULATION; BONE DISEASES; BONE TRANSPLANTATION; COLLAGEN; CRYOPRESERVATION; FIBROBLASTS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; OSTEOBLASTS; OSTEOCYTES; OSTEOGENESIS; PLATELET-RICH PLASMA; RANDOM ALLOCATION; RATS; RATS, WISTAR; SKULL; WOUND HEALING;

EID: 84878813412     PISSN: 15230899     EISSN: 17088208     Source Type: Journal    
DOI: 10.1111/j.1708-8208.2011.00419.x     Document Type: Article

References (51)

1. Hallman M, Thor A. Bone substitutes and growth factors as an alternative/complement to autogenous bone for grafting in implant dentistry. Periodontol 2000 2008; 47:172-192.
2. Kasten P, Vogel J, Geiger F, Niemeyer P, Luginbühl R, Szalay K. The effect of platelet-rich plasma on healing in critical-size long-bone defects. Biomaterials 2008; 29:3983-3992.
3. Bostrom MP, Seigerman DA. The clinical use of allografts, demineralized bone matrices, synthetic bone graft substitutes and osteoinductive growth factors: a survey study. HSS J 2005; 1:9-18.
4. Urist MR. Bone transplants and implants. Philadelphia, PA: JB Lipicott, 1980:331-368.
5. Cenni E, Perut F, Ciapetti G, etal. In vitro evaluation of freeze-dried bone allografts combined with platelet rich plasma and human bone marrow stromal cells for tissue engineering. J Mater Sci Mater Med 2009; 20:45-50.
6. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 85:638-646.
7. Filho Cerruti H, Kerkis I, Kerkis A, etal. Allogenous bone grafts improved by bone marrow stem cells and platelet growth factors: clinical case reports. Artif Organs 2007; 31:268-273.
8. Plachokova AS, Nikolidakis D, Mulder J, Jansen JA, Creugers NH. Effect of platelet-rich plasma on bone regeneration in dentistry: a systematic review. Clin Oral Implants Res 2008; 19:539-545.
9. Kassolis JD, Reynolds MA. Evaluation of the adjunctive benefits of platelet-rich plasma in subantral sinus augmentation. J Craniofac Surg 2005; 16:280-287.
10. Dallari D, Fini M, Stagni C, etal. In vivo study on the healing of bone defects treated with bone marrow stromal cells, platelet-rich plasma, and freeze-dried bone allografts, alone and in combination. J Orthop Res 2006; 24:877-888.
11. Kim SG, Kim WK, Park JC, Kim HJ. A comparative study of osseointegration of Avana implants in a demineralized freeze-dried bone alone or with platelet-rich plasma. J Oral Maxillofac Surg 2002; 60:1018-1025.
12. Grageda E, Lozada JL, Boyne PJ, Caplanis N, McMillan PJ. Bone formation in the maxillary sinus by using platelet-rich plasma: an experimental study in sheep. J Oral Implantol 2005; 31:2-17.
13. Jensen TB, Rahbek O, Overgaard S, Søballe K. Platelet rich plasma and fresh frozen bone allograft as enhancement of implant fixation. An experimental study in dogs. J Orthop Res 2004; 22:653-658.
14. Jensen TB, Rahbek O, Overgaard S, Søballe K. No effect of platelet-rich plasma with frozen or processed bone allograft around noncemented implants. Int Orthop 2005; 29:67-72.
15. Palmisano W, Degen M, Block MS. Craniotomy bone defect healing with PRP combined with mineralized bone. J Oral Maxillofac Surg 2002; 60:39.
16. Harris D, Farrell B, Block MS. Zygomatic arch defects grafted with mineralized bone with PRP or PPP in dogs. J Oral Maxillofac Surg 2003; 61:42.
17. Dudziak ME, Block MS. Ridge augmentation with PRP/PPP and mineralized bone in dogs. J Oral Maxillofac Surg 2003; 61:41-42.
18. Aghaloo TL, Moy PK, Freymiller EG. Evaluation of platelet-rich plasma in combination with freeze-dried bone in the rabbit cranium. A pilot study. Clin Oral Implants Res 2005; 16:250-257.
19. Wallace SS, Froum SJ. Effect of maxillary sinus augmentation on the survival of endosseous dental implants. A systematic review. Ann Periodontol 2003; 8:328-343.
20. Sánchez AR, Sheridan PJ, Kupp LI. Is platelet-rich plasma the perfect enhancement factor? A current review. Int J Oral Maxillofac Implants 2003; 18:93-103.
21. Anitua E, Sánchez M, Nurden AT, Nurden P, Orive G, Andía I. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 2006; 24:227-234.
22. Marx RE. Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent 2001; 10:225-228.
23. Heyligers IC, Klein-Nulend J. Detection of living cells in non-processed but deep-frozen bone allografts. Cell Tissue Bank 2005; 6:25-31.
24. Stacchi C, Orsini G, Di Iorio D, Breschi L, Di Lenarda R. Clinical, histological, and histomorphometric analyses of regenerated bone in maxillary sinus augmentation using fresh frozen human bone allografts. J Periodontol 2008; 79:1789-1796.
25. Messora MR, Nagata MJH, Mariano RC, etal. Bone healing in critical-size defects treated with platelet-rich plasma: a histologic and histometric study in rat calvaria. J Periodontal Res 2008; 43:217-223.
26. Messora MR, Nagata MJ, Dornelles RC, etal. Bone healing in critical-size defects treated with platelet-rich plasma activated by two different methods. A histologic and histometric study in rat calvaria. J Periodontal Res 2008; 43:723-729.
27. Reikerås O, Sigurdsen UW, Shegarfi H. Impact of freezing on immunology and incorporation of bone allograft. J Orthop Res 2010; 28:1215-1219.
28. Bos GD, Goldberg VM, Zika JM. Immune responses of rats to frozen bone allografts. J Bone Joint Surg Am 1983; 65:239-246.
29. Muscolo DL, Kawai S, Ray RD. In vitro studies of transplantation antigens present on bone cells in the rat. J Bone Joint Surg Br 1977; 59:342-348.
30. Stevenson S, Li XQ, Martin B. The fate of cancellous and cortical bone after transplantation of fresh and frozen tissue-antigen-matched and mismatched osteochondral allografts in dogs. J Bone Joint Surg Am 1991; 73:1143-1156.
31. Stevenson S, Li XQ, Davy DT, Klein L, Goldberg VM. Critical biological determinants of incorporation of non-vascularized cortical bone grafts. Quantification of a complex process and structure. J Bone Joint Surg Am 1997; 79:1-16.
32. Muscolo DL, Ayerza MA, Calabrese ME, etal. Human leukocyte antigen matching, radiographic score, and histological findings in massive frozen bone allografts. Clin Orthop Relat Res 1996; 326:115-126.
33. Stevenson S. The immune response to osteochondral allografts in dogs. J Bone Joint Surg Am 1987; 69:573-582.
34. Strong DM, Friedlaender GE, Tomford WW, etal. Immunologic responses in human recipients of osseous and osteochondral allografts. Clin Orthop Relat Res 1996; 326:107-114.
35. Reikerås O, Shegarfi H, Naper C, Reinholt FP, Rolstad B. Impact of MHC mismatch and freezing on bone graft incorporation: an experimental study in rats. J Orthop Res 2008; 26:925-931.
36. Virolainen P, Vuorio E, Aro HT. Different healing rates of bone autografts, syngeneic grafts, and allografts in an experimental rat model. Arch Orthop Trauma Surg 1997; 116:486-491.
37. Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg 2004; 62:489-496.
38. Roussy Y, Bertrand Duchesne MP, Gagnon G. Activation of human platelet-rich plasmas: effect on growth factors release, cell division and in vivo bone formation. Clin Oral Implants Res 2007; 18:639-648.
39. Fréchette JP, Martineau I, Gagnon G. Platelet-rich plasmas: growth factor content and roles in wound healing. J Dent Res 2005; 84:434-439.
40. Gruber R, Kandler B, Fischer MB, Watzek G. Osteogenic differentiation induced by bone morphogenetic proteins can be suppressed by platelet-released supernatant in vitro. Clin Oral Implants Res 2006; 17:188-193.
41. Choi BH, Zhu SJ, Kim BY, Huh JY, Lee SH, Jung JH. Effect of platelet-rich plasma (PRP) concentration on the viability and proliferation alveolar bone cells: an in vitro study. Int J Oral Maxillofac Surg 2005; 34:420-424.
42. Ogino Y, Ayukawa Y, Kukita T, Koyano K. The contribution of platelet derived growth factor, transforming growth factor-beta1, and insulin-like growth factor-I in platelet-rich plasma to the proliferation of osteoblast-like cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101:724-729.
43. Efeoglu C, Akcay YD, Erturk S. A modified method for preparing platelet-rich plasma: an experimental study. J Oral Maxillofac Surg 2004; 62:1403-1407.
44. Dugrillon A, Eichler H, Kern S, etal. Autologous concentrated platelet-rich plasma (cPRP) for local application in bone regeneration. Int J Oral Maxillofac Surg 2002; 31:615-619.
45. Maitz P, Kandler B, Fischer MB, etal. Activated platelets retain their potential to induce osteoclast-like cell formation in murine bone marrow cultures. Platelets 2006; 17:477-483.
46. Ogino Y, Ayukawa Y, Kukita T, etal. Platelet-rich plasma suppresses osteoclastogenesis by promoting the secretion of osteoprotegerin. J Periodontal Res 2009; 44:217-224.
47. Cenni E, Avnet S, Fotia C, Salerno M, Baldini N. Platelet-rich plasma impairs osteoclast generation from human precursors of peripheral blood. J Orthop Res 2010; 28:792-797.
48. Nagata MJ, Messora M, Pola N, etal. Influence of the ratio of particulate autogenous bone graft/platelet-rich plasma on bone healing in critical-size defects: a histologic and histometric study in rat calvaria. J Orthop Res 2010; 28:468-473.
49. Grageda E. Platelet-rich plasma and bone graft materials: a review and a standardized research protocol. Implant Dent 2004; 13:301-309.
50. Weibrich G, Kleis WK, Hafner G, Hitzler WE. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg 2002; 30:97-102.
51. Martineau I, Lacoste E, Gagnon G. Effects of calcium and thrombin on growth factor release from platelet concentrates: kinetics and regulation of endothelial cell proliferation. Biomaterials 2004; 25:4489-4502.