Local functional connectivity as a pre-surgical tool for seizure focus identification in non-lesion, focal epilepsy

Frontiers in Neurology

Volumn 4 MAY, Issue , 2013, Pages

  Weaver, K E ^a,b   Chaovalitwongse, W A ^a,b   Novotny, E J ^b,c   Poliakov, A ^c   Grabowski, T G ^a,b   Ojemann, J G ^a,b,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c SEATTLE CHILDREN S HOSPITAL   (United States)

Author keywords

Contralateral; Epilepsy surgery; Focal epilepsy; Functional connectivity; Non lesion; Pre operative evaluation; ReHo; Resting state fMRI

Indexed keywords

ADULT; ARTICLE; BOLD SIGNAL; BRAIN MAPPING; CASE REPORT; ELECTRODE; EPILEPTIC FOCUS; FEMALE; FOCAL EPILEPSY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREOPERATIVE PERIOD; SEIZURE;

EID: 84878803701     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2013.00043     Document Type: Article

References (47)

1. Barabási, A.-L., and Albert, R. (1999). Emergence of scaling in random networks. Science 286, 509-512.
2. Bettus, G., Bartolomei, F., Confort-Gouny, S., Guedj, E., Chauvel, P., Cozzone, P. J., et al. (2010). Role of resting state functional connectivity MRI in presurgical investigation of mesial temporal lobe epilepsy. J. Neurol. Neurosurg. Psychiatr. 81, 1147-1154.
3. Bettus, G., Guedj, E., Joyeux, F., Confort-Gouny, S., Soulier, E., Laguitton, V., et al. (2009). Decreased basal fMRI functional connectivity in epileptogenic networks and contralateral compensatory mechanisms. Hum. Brain Mapp. 30, 1580-1591.
4. Biswal, B. B., Mennes, M., Zuo, X.-N., Gohel, S., Kelly, C., Smith, S. M., et al. (2010). Toward discovery science of human brain function. Proc. Natl. Acad. Sci. U.S.A. 107, 4734-4739.
5. Bullmore, E., and Sporns, O. (2009). Complex brain networks: graph theoretical analysis of structural and functional systems. Nat. Rev. Neurosci. 10, 186-198.
6. Burwell, R. D. (2000). The parahippocampal region: corticocortical connectivity. Ann. N. Y. Acad. Sci. 911, 25-42.
7. Chen, J. W., and Wasterlain, C. G. (2006). Status epilepticus: pathophysiology and management in adults. Lancet Neurol. 5, 246-256.
8. Damoiseaux, J. S., Rombouts, S. A. R. B., Barkhof, F., Scheltens, P., Stam, C. J., Smith, S. M., et al. (2006). Consistent resting-state networks across healthy subjects. Proc. Natl. Acad. Sci. U.S.A. 103, 13848-13853.
9. de Tisi, J., Bell, G. S., Peacock, J. L., McEvoy, A. W., Harkness, W. F., Sander, J. W., et al. (2011). The long-term outcome of adult epilepsy surgery, patterns of seizure remission, and relapse: a cohort study. Lancet 378, 1388-1395.
10. Duncan, J. S. (2010). Imaging in the surgical treatment of epilepsy. Nat. Rev. Neurol. 6, 537-550.
11. Eichenbaum, H., Yonelinas, A. R., and Ranganath, C. (2007). The medial temporal lobe and recognition memory. Annu. Rev. Neurosci. 30, 123-152.
12. Engel, J. Jr., McDermott, M. P., Wiebe, S., Langfitt, J. T., Stern, J. M., Dewar, S., et al. (2012). Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA 307, 922-930.
13. Fox, M. D., and Greicius, M. (2010). Clinical applications of resting state functional connectivity. Front. Syst. Neurosci. 4:19. doi:10.3389/fnsys.2010.00019
14. Fox, M. D., and Raichle, M. E. (2007). Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat. Rev. Neurosci. 8, 700-711.
15. He, Y., Chen, Z. J., and Evans, A. C. (2007). Small-world anatomical networks in the human brain revealed by cortical thickness from MRI. Cereb. Cortex 17, 2407-2419.
16. Honey, C. J., Sporns, O., Cammoun, L., Gigandet, X., Thiran, J. P., Meuli, R., et al. (2009). Predicting human resting-state functional connectivity from structural connectivity. Proc. Natl. Acad. Sci. U.S.A. 106, 2035-2040.
17. Isnard, J., Guénot, M., Ostrowsky, K., Sindou, M., and Mauguière, F. (2000). The role of the insular cortex in temporal lobe epilepsy. Ann. Neurol. 48, 614-623.
18. Jayakar, P., Dunoyer, C., Dean, P., Ragheb, J., Resnick, T., Morrison, G., et al. (2008). Epilepsy surgery in patients with normal or nonfocal MRI scans: integrative strategies offer long-term seizure relief. Epilepsia 49, 758-764.
19. Kahn, I., Andrews-Hanna, J. R., Vincent, J. L., Snyder, A. Z., and Buckner, R. L. (2008). Distinct cortical anatomy linked to subregions of the medial temporal lobe revealed by intrinsic functional connectivity. J. Neurophysiol. 100, 129-139.
20. Keller, C. J., Bickel, S., Entz, L., Ulbert, I., Milham, M. P., Kelly, C., et al. (2011). Intrinsic functional architecture predicts electrically evoked responses in the human brain. Proc. Natl. Acad. Sci. U.S.A. 108, 10308-10313.
21. Laufs, H. (2012). Functional imaging of seizures and epilepsy. Curr. Opin. Neurol. 25, 194-200.
22. Mankinen, K., Long, X.-Y., Paakki, J.-J., Harila, M., Rytky, S., and Tervonen, O. (2011). Alterations in regional homogeneity of baseline brain activity in pediatric temporal lobe epilepsy. Brain Res. 1373, 221-229.
23. Mauguière, F., and Ryvlin, P. (2004). The role of PET in presurgical assessment of partial epilepsies. Epileptic Disord. 6, 193-215.
24. McIntyre, D. C., and Gilby, K. L. (2008). Mapping seizure pathways in the temporal lobe. Epilepsia 49, 23-30.
25. Morgan, V. L., Sonmezturk, H. H., Gore, J. C., and Abou-Khalil, B. (2012). Lateralization of temporal lobe epilepsy using resting functional magnetic resonance imaging connectivity of hippocampal networks. Epilepsia 53, 1628-1635.
26. Muldoon, S. F., Soltesz, I., and Cossart, R. (2013). Spatially clustered neuronal assemblies comprise the microstructure of synchrony in chronically epileptic networks. Proc. Natl. Acad. Sci. U.S.A. 110, 3567-3572.
27. Multani, P., Myers, R. H., Blume, H. W., Schomer, D. L., and Sotrel, A. (1994). Neocortical dendritic pathology in human partial epilepsy: a quantitative Golgi study. Epilepsia 35, 728-736.
28. Nguyen, D. K., Nguyen, D. B., Malak, R., and Bouthillier, A. (2009). Insular cortex epilepsy: an overview. Can. J. Neurol. Sci. 36(Suppl. 2), S58-S62.
29. Pan, J. W., Spencer, D. D., Kuzniecky, R., Duckrow, R. B., Hetherington, H., and Spencer, S. S. (2012). Metabolic networks in epilepsy by MR spectroscopic imaging. Acta Neurol. Scand. 126, 411-420.
30. Ranganath, C., and Ritchey, M. (2012). Two cortical systems for memory-guided behaviour. Nat. Rev. Neurosci. 13, 713-726.
31. Roper, S. N., Lévesque, M. F., Sutherling, W. W., and Engel, J. Jr. (1993). Surgical treatment of partial epilepsy arising from the insular cortex. Report of two cases. J. Neurosurg. 79, 266-269.
32. Rosenow, F., and Lüders, H. (2001). Presurgical evaluation of epilepsy. Brain 124, 1683-1700.
33. Sankar, R., Shin, D. H., Liu, H., Mazarati, A., de Vasconcelos, A., and Wasterlain, C. G. (1998). Patterns of status epilepticus-induced neuronal injury during development and long-term consequences. J. Neurosci. 18, 8382-8393.
34. Sequeira, K. M., Tabesh, A., Sainju, R. K., Desantis, S. M., Naselaris, T., Joseph, J. E., et al. (2013). Perfusion network shift during seizures in medial temporal lobe epilepsy. PLoS ONE 8:e53204. doi:10.1371/journal.pone.0053204
35. Shimony, J. S., Zhang, D., Johnston, J. M., Fox, M. D., Roy, A., and Leuthardt, E. C. (2009). Resting-state spontaneous fluctuations in brain activity: a new paradigm for presurgical planning using fMRI. Acad. Radiol. 16, 578-583.
36. Siegel, A. M., Jobst, B. C., Thadani, V. M., Rhodes, C. H., Lewis, P. J., Roberts, D. W., et al. (2001). Medically intractable, localization-related epilepsy with normal MRI: presurgical evaluation and surgical outcome in 43 patients. Epilepsia 42, 883-888.
37. Spencer, S., and Huh, L. (2008). Outcomes of epilepsy surgery in adults and children. Lancet Neurol. 7, 525-537.
38. Stufflebeam, S. M., Liu, H., Sepulcre, J., Tanaka, N., Buckner, R. L., and Madsen, J. R. (2011). Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging. J. Neurosurg. 114, 1693-1697.
39. Taylor, K. S., Seminowicz, D. A., and Davis, K. D. (2009). Two systems of resting state connectivity between the insula and cingulate cortex. Hum. Brain Mapp. 30, 2731-2745.
40. Thom, M. (2004). Neuropathological findings in epilepsy. Curr. Diagn. Pathol. 10, 93-105.
41. Thornton, R., Laufs, H., Rodionov, R., Cannadathu, S., Carmichael, D. W., Vulliemoz, S., et al. (2010). EEG correlated functional MRI and postoperative outcome in focal epilepsy. J. Neurol. Neurosurg. Psychiatr. 81, 922-927.
42. Wiebe, S., Blume, W. T., Girvin, J. P., and Eliasziw, M. (2001). Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N. Engl. J. Med. 345, 311-318.
43. Won, H. J., Chang, K.-H., Cheon, J.-E., Kim, H. D., Lee, D. S., Han, M. H., et al. (1999). Comparison of MR imaging with PET and IctalSPECT in 118 patients with intractable epilepsy. AJNR Am. J. Neuroradiol. 20, 593-599.
44. Wong, M., and Guo, D. (in press). Dendritic spine pathology in epilepsy: cause or consequence? Neuroscience. doi:10.1016/j.neuroscience.2012.03.048
45. Zang, Y., Jiang, T., Lu, Y., He, Y., and Tian, L. (2004). Regional homogeneity approach to fMRI data analysis. Neuroimage 22, 394-400.
46. Zhong, Y., Lu, G., Zhang, Z., Jiao, Q., Li, K., and Liu, Y. (2011). Altered regional synchronization in epileptic patients with generalized tonic-clonic seizures. Epilepsy Res. 97, 83-91.
47. Zijlmans, M., Huiskamp, G., Hersevoort, M., Seppenwoolde, J.-H., van Huffelen, A. C., and Leijten, F. S. S. (2007). EEG-fMRI in the preoperative work-up for epilepsy surgery. Brain 130, 2343-2353.