Metabolomic Profiling Unravels DNA Adducts in Human Breast That Are Formed from Peroxidase Mediated Activation of Estrogens to Quinone Methides

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Gaikwad, Nilesh W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABIETAQUINONE METHIDE; ADENINE; ESTROGEN; HYDROGEN PEROXIDE; LACTOPEROXIDASE; MANGANESE DIOXIDE; PEROXIDASE; DNA ADDUCT; INDOLE DERIVATIVE; MANGANESE DERIVATIVE; OXIDE; QUINONE METHIDE; SOLUTION AND SOLUBILITY;

ADULT; ARTICLE; BREAST; BREAST CANCER; CARCINOGENESIS; COVALENT BOND; CULTURE MEDIUM; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; ELECTROPHILICITY; ESTROGEN METABOLISM; FEMALE; GENE MUTATION; HORMONAL REGULATION; HUMAN; HUMAN TISSUE; METABOLOMICS; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; BIOPSY; BIOSYNTHESIS; CHEMISTRY; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; METABOLISM; METABOLOME; MIDDLE AGED; SOLUTION AND SOLUBILITY;

ADENINE; ADULT; BIOPSY; BREAST; CHROMATOGRAPHY, LIQUID; DNA ADDUCTS; DNA DAMAGE; ESTROGENS; FEMALE; HUMANS; HYDROGEN PEROXIDE; INDOLEQUINONES; LACTOPEROXIDASE; MANGANESE COMPOUNDS; METABOLOME; MIDDLE AGED; OXIDES; SOLUTIONS; TANDEM MASS SPECTROMETRY;

EID: 84878785477     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065826     Document Type: Article

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