Full-field electroretinogram findings in children in the atropine treatment for myopia (ATOM2) study

Documenta Ophthalmologica

Volumn 126, Issue 3, 2013, Pages 177-186

  Chia, Audrey ^a,b   Li, Wen ^c,d   Tan, Donald ^a,b   Luu, Chi D ^a,e  

^a SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^b SINGAPORE NATIONAL EYE CENTRE   (Singapore)

^c SINGAPORE CLINICAL RESEARCH INSTITUTE   (Singapore)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Atropine; Electrophysiology; Electroretinogram; Myopia; Refractive error

Indexed keywords

ATROPINE; CYCLOPENTOLATE;

A WAVE; ARTICLE; B WAVE; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DARK ADAPTATION; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; ELECTRORETINOGRAM; FEMALE; HUMAN; LONGITUDINAL STUDY; MALE; MYOPIA; PHOTOPIC VISION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; TREATMENT DURATION;

ATROPINE; CHILD; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRORETINOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MYDRIATICS; MYOPIA; OPHTHALMIC SOLUTIONS; RETINA; RETROSPECTIVE STUDIES;

EID: 84878757293     PISSN: 00124486     EISSN: 15732622     Source Type: Journal    
DOI: 10.1007/s10633-012-9372-8     Document Type: Article

References (22)

1. Perlman I, Meyer E, Haim T, Zonis S (1984) Retinal function in high refractive error assessed electroretinographically. Br J Ophthalmol 68:79-84
2. Chen JF, Elsner AE, Burns S, Hansen RM, Lou PL, Kwong KK, Fulton AB (1992) The effects of eye shape on retinal responses. Clin Vis Sci 7:520-530
3. Westall CA, Dhaliwal HS, Panton CM, Sigesmun D, Levin AV, Nischal KK, Heon E (2001) Values of electroretinogram responses according to axial length. Doc Ophthalmol 102:115-130
4. Kawabata H, Adachi-Usami E (1997) Multifocal electroretinogram in myopia. Invest Ophthalmol Vis Sci 38:2844-2851
5. Chen JC, Brown B, Schmid KL (2006) Delayed mfERG responses in myopia. Vis Res 46:1221-1229
6. Luu CD, Lau AM, Lee SY (2006) Multifocal electroretinogram in adults and children with myopia. Arch Ophthalmol 124:328-334
7. Wolsley CJ, Saunders KJ, Silvestri G, Anderson RS (2008) Investigation of changes in the myopic retina using multifocal electroretinograms, optical coherence tomography and peripheral resolution acuity. Vis Res 48:1554-1561
8. Chia A, Chua WH, Cheung YB, Wong WL, Lingham A, Fong A, Tan D (2012) Atropine for the Treatment of childhood myopia: safety and efficacy of 0.5%, 0.1% and 0.01% doses (ATOM2). Ophthalmology 119:347-354
9. Peachey NS, Alexander KR, Fishman GA (1989) The luminance-response function of the dark-adapted human electroretinogram. Vis Res 29:263-270
10. Shih YF, Chen CH, Chou AC, Ho TC, Lin LL, Hung PT (1999) Effects of different concentrations of atropine on controlling myopia in myopic children. J Ocul Pharmacol Ther 15:85-90
11. Shih YF, Hsiao CK, Chen CJ, Chang CW, Hung PT, Lin LL (2001) An intervention trial on efficacy of atropine and multi-focal glasses incontrolling myopic progression. Acta Ophthalmol Scand 79:233-236
12. Chua WH, Balakrishnan V, Chan YH, Tong L, Ling Y, Quah BL, Tan D (2006) Atropine for the treatment of childhood myopia. Ophthalmology 113:2285-2291
13. Tong L, Huang XL, Koh AL, Zhang X, Tan DT, Chua WH (2009) Atropine for the treatment of childhood myopia: effect on myopia progression after cessation of atropine. Ophthalmology 116:572-579
14. Barathi VA, Weon SR, Beuerman RW (2009) Expression of muscarinic receptors in human and mouse sclera and their role in the regulation of scleral fibroblast proliferation. Mol Vis 15:1277-1293
15. Barathi VA, Beuerman RW (2011) Molecular mechanisms of muscarinic receptors in mouse scleral fibroblasts: prior to and after induction of experimental myopia with atropine treatment. Mol Vis 17:680-692
16. Luu CD, Lau AMI, Koh AHC, Tan D (2005) Multifocal electroretinogram in children on atropine treatment for myopia. Br J Ophthalmol 89:151-153
17. Crewther DP, Crewther SG, Xie RA (1996) Changes in eye growth produced by drugs which affect retinal ON or OFF responses to light. J Ocul Pharmacol Ther 12:193-208
18. Crewther DP (2000) The role of photoreceptors in the control of refractive state. Prog Ret Eye Res 19:421-457
19. Diether S, Gekeler F, Schaeval F (2001) Changes in contrast sensitivity induces by defocus and their possible relations to emmetropization in the chicken. Invest Ophthal Vis Sci 42:3072-3079
20. Crewther DP, Crewther SG (2002) Refractive compensation to optical defocus depends on the temporal profile of luminance modulation of the environment. NeuroReport 13:1029-1032
21. Crewther SG, Crewther DP (2003) Inhibition of retinal ON/OFF systems differentially affects refractive compensation to defocus. NeuroReport 14:1233-1237
22. Chen JC, Brown B, Schmid KL (2006) Slow flash multifocal electroretinogram in myopia. Vis Res 46:2869-2876