Crosstalk between Fas and JNK determines lymphocyte apoptosis after ionizing radiation

Radiation Research

Volumn 179, Issue 6, 2013, Pages 725-736

  Praveen, Koganti ^a   Saxena, Nandita ^a,b  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

^b DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; IONIZING RADIATION; LYMPHOCYTE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGENS, CD95; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENZYME ACTIVATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LYMPHOCYTES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECEPTOR CROSS-TALK; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84878699292     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR3189.1     Document Type: Article

References (30)

1. Nagata S. Apoptosis by death factor. Cell 1997; 88:355-65.
2. Tschopp J, Irmler M, Thome M. Inhibition of Fas death signals by FLIPs. Curr Opin Immunol 1998; 10:552-58.
3. Kasibhatla A, Brunner T, Genestier L, Echeverri F, Mahboubi A, Green DR. DNA damaging agents induce expression of Fas Ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol Cell 1998; 1:543-51.
4. Reap EA, Roof K, Maynor K, Borrero M, Booker J, Cohen PL. Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions. Proc Natl Acad Sci U S A 1997; 94:5750-55.
5. Belka C, Marini P, Budach W, Schulze-Osthoff K, Lang F. Radiation-induced apoptosis in human lymphocytes and lymphoma cells critically relies on the up-regulation of CD95/Fas/APO-1ligand. Radiat Res 1998; 149:588-95.
6. Sheard MA, Krammer PH, Zaloudik J. Fractionated gammairradiation renders tumor cells more responsive to apoptotic signals through CD95. Br J Cancer 1999; 80:1689-96.
7. Sheard MA. Ionizing radiation as a response-enhancing agent for CD95-mediated apoptosis. Int J Cancer 2001; 96:213-20.
8. Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M. Reactive oxygen species promote TNF-alpha induced death and sustained JNK activation by inhibiting MAP kinase phosphatase. Cell 2005; 120:649-61.
9. Chen YR, Meyer CF, Tan TH. Persistent activation of c-Jun Nterminal kinase 1 (JNK1) in gamma radiation-induced apoptosis. J Biol Chem 1996; 271:631-4.
10. Dong C, Davis RJ, Flavell RA. MAP kinase in the immune response. Annu Rev Immunol 2002: 20; 55-72.
11. Goillot E, Raingeaud J, Ranger A, Tepper RI, Davis RJ, Harlow E, et al. Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway. Proc Natl Acad Sci U S A 1997; 94:3302-07.
12. Kuwabara M, Takahashi K, Inanmi O. Induction of apoptosis through the activation of SAPK/JNK followed by the expression of death receptor Fas in X-irradiated cells. J Radiat Res 2003; 44:203-9.
13. Bernhard E J, McKenna W G, Muschel R J. Cyclin expression and G2-phase delay after irradiation. Radiat Res 1994; 138:S64-S7.
14. Chen YR, Wang X, Templeton D, Davis RJ, Tan TH. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem 1996; 271:31929-36
15. Faris M, Latinis KM, Kempiak SJ, Koretzky GA, Nel A. Stress-Induced Fas Ligand expression in T cell is mediated through a MEK Kinase 1-regulated response element in the Fas ligand promoter. Mol Cell Biol 1998; 18:5414-24.
16. He JS, Ostergaard HL. CTLs contain and use intracellular stores of Fas L distinct from cytolytic granules. J Immunol 2007;179: 2339-48.
17. Kim PK, Wang Y, Gambotto A, Kim YM, Weller R, Zuckerbraun BS, et al. Hepatocyte Fas-associating death domain protein/ mediator of receptor-induced toxicity (FADD/MORT1) levels increase in response to pro-apoptotic stimuli. J Biol Chem 2002; 277:38855-62.
18. Newton K, Strasser A. Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling: implication for cancer therapy. J Exp Med 2000: 191: 195-200.
19. Abrahams VM, Kamsteeg M, Mor G. The Fas/Fas Ligand System and Cancer. Mol Biotechnol 2003; 25:19-30.
20. Liu J, Lin A. Role of JNK activation in apoptosis: a double-edged sword. Cell Res. 2005; 15:36-42.
21. Chang L, Kamata H, Solinas G, Luo JL, Maeda S, Venuprasad K, et al. The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Cell 2006; 124:601-13.
22. Verbrugge I, Maas C, Heijkoop M, Verheij M, Brost J. Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/ Fas via c-FLIP down regulation. Cell death and differentiation 2010; 17:551-61.
23. Eichhorst ST, Muller M, Li-Weber M, Schulze-Bergkamen H, Angel P, Krammer PH. A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs. Mol Cell Biol 2000; 20:7826-37
24. Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx a novel Fas-binding protein that activates JNK and apoptosis. Cell 1997; 89:1067-76.
25. Hofmann TG, Moller A, Hehner SP, Welsch D, Droge W, Schmitz ML. CD95-induced JNK activation signals are transmitted by the death-inducing signaling complex (DISC), but not by Daxx. Int J Cancer 2001; 93:185-91
26. Haimovitz-Friedman A, Kan CC, Ehleiter D, Persaud RS, McLoughlin M, Fuks Z, et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med. 1994; 180:525-35
27. Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S, et al. Requirement for ceramide initiated JNK/SAPKs signalling in stress-induced apoptosis. Nature 1996; 380:75-79.
28. Herr I, Wilhelm D, Bohler T, Angel P, Debatin KM. Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J. 1997; 16:6200-8
29. Li LH, Wu LJ, Tashiro S, Onodera S, Uchiumi F, Ikejima T. Silibinin prevents UV-induced HaCaT cell apoptosis partly through inhibition of caspase-8 pathway. Biol Pharm Bull. 2006; 29:1096-101.
30. Li BH, Zhou YB, Guo SB, Wang CB. Polypeptide from Chlamysfarreri inhibits UVB-induced HaCaT cells apoptosis via inhibition CD95 pathway and reactive oxygen species. Free Radic Res. 2007; 41:1224-32.