Promoter methylation of Egr-1 site contributes to fetal hypoxia-mediated PKCε gene repression in the developing heart

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 304, Issue 9, 2013, Pages

  Chen, Man ^a   Xiong, Fuxia ^a   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

DNA methylation; Egr 1; Heart; Hypoxia; PKC

Indexed keywords

ACTIN; EARLY GROWTH RESPONSE FACTOR 1; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; PROTEIN KINASE C EPSILON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA MODIFICATION; FEMALE; FETUS; FETUS DEVELOPMENT; FETUS HYPOXIA; GENE REPRESSION; HEART DEVELOPMENT; MALE; METHYLATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE;

DNA METHYLATION; EGR-1; HEART; HYPOXIA; PKCΕ;

ANIMALS; ANIMALS, NEWBORN; ANTIMETABOLITES; AZACITIDINE; BINDING SITES; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; EARLY GROWTH RESPONSE PROTEIN 1; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPIGENESIS, GENETIC; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; FETAL HYPOXIA; HEART; MALE; MYOCARDIUM; PREGNANCY; PROTEIN KINASE C-EPSILON; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; SEX CHARACTERISTICS;

EID: 84878660442     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00461.2012     Document Type: Article

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