메뉴 건너뛰기




Volumn 38, Issue 8, 2013, Pages 1397-1406

Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats

Author keywords

Acoustic startle response; Allopregnanolone; Behaviour; Hippocampus; Neurodevelopment; Pregnenolone sulphate; Prepulse inhibition; Rat; Schizophrenia

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; FINASTERIDE; NEUROSTEROID; PREGNENOLONE SULFATE;

EID: 84878656301     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2012.12.007     Document Type: Article
Times cited : (17)

References (55)
  • 4
    • 21744447595 scopus 로고    scopus 로고
    • Neurosteroids: endogenous regulators of the GABA(A) receptor
    • Belelli D., Lambert J.J. Neurosteroids: endogenous regulators of the GABA(A) receptor. Nat. Rev. Neurosci. 2005, 6(7):565-575.
    • (2005) Nat. Rev. Neurosci. , vol.6 , Issue.7 , pp. 565-575
    • Belelli, D.1    Lambert, J.J.2
  • 5
    • 0033953033 scopus 로고    scopus 로고
    • Neurosteroids: biosynthesis and function of these novel neuromodulators
    • Compagnone N.A., Mellon S.H. Neurosteroids: biosynthesis and function of these novel neuromodulators. Front. Neuroendocrinol. 2000, 21(1):1-56.
    • (2000) Front. Neuroendocrinol. , vol.21 , Issue.1 , pp. 1-56
    • Compagnone, N.A.1    Mellon, S.H.2
  • 7
    • 0033462180 scopus 로고    scopus 로고
    • Effects of a naturally occurring neurosteroid on GABAA IPSCs during development in rat hippocampal or cerebellar slices
    • Cooper E.J., Johnston G.A., Edwards F.A. Effects of a naturally occurring neurosteroid on GABAA IPSCs during development in rat hippocampal or cerebellar slices. J. Physiol. 1999, 521(Pt 2):437-449.
    • (1999) J. Physiol. , vol.521 , Issue.PART 2 , pp. 437-449
    • Cooper, E.J.1    Johnston, G.A.2    Edwards, F.A.3
  • 8
    • 0041592614 scopus 로고    scopus 로고
    • Perinatal hypothyroidism effects on neuromotor competence, novelty-directed exploratory and anxiety-related behaviour and learning in rats
    • Darbra S., Garau A., Balada F., Sala J., Martí-Carbonell M.A. Perinatal hypothyroidism effects on neuromotor competence, novelty-directed exploratory and anxiety-related behaviour and learning in rats. Behav. Brain Res. 2003, 143:209-215.
    • (2003) Behav. Brain Res. , vol.143 , pp. 209-215
    • Darbra, S.1    Garau, A.2    Balada, F.3    Sala, J.4    Martí-Carbonell, M.A.5
  • 9
    • 68549097836 scopus 로고    scopus 로고
    • Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABAA receptor modulators in adulthood
    • Darbra S., Pallarès M. Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABAA receptor modulators in adulthood. Int. J. Dev. Neurosci. 2009, 27:617-625.
    • (2009) Int. J. Dev. Neurosci. , vol.27 , pp. 617-625
    • Darbra, S.1    Pallarès, M.2
  • 10
    • 77950689114 scopus 로고    scopus 로고
    • Alterations in neonatal neurosteroids affect exploration during adolescence and prepulse inhibition in adulthood
    • Darbra S., Pallarès M. Alterations in neonatal neurosteroids affect exploration during adolescence and prepulse inhibition in adulthood. Psychoneuroendocrinology 2010, 35(4):525-535.
    • (2010) Psychoneuroendocrinology , vol.35 , Issue.4 , pp. 525-535
    • Darbra, S.1    Pallarès, M.2
  • 11
    • 78149498873 scopus 로고    scopus 로고
    • Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour
    • Darbra S., Pallarès M. Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour. Behav. Brain Res. 2011, 216(2):705-711.
    • (2011) Behav. Brain Res. , vol.216 , Issue.2 , pp. 705-711
    • Darbra, S.1    Pallarès, M.2
  • 12
    • 81155148724 scopus 로고    scopus 로고
    • Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats
    • Darbra S., Pallarès M. Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats. Neuropsychobiology 2012, 65(1):20-27.
    • (2012) Neuropsychobiology , vol.65 , Issue.1 , pp. 20-27
    • Darbra, S.1    Pallarès, M.2
  • 13
    • 84857189114 scopus 로고    scopus 로고
    • Allopregnanolone infused into the dorsal (CA1) hippocampus increases prepulse inhibition of startle response in Wistar rats
    • Darbra S., Mòdol L., Pallarès M. Allopregnanolone infused into the dorsal (CA1) hippocampus increases prepulse inhibition of startle response in Wistar rats. Psychoneuroendocrinology 2012, 37(4):581-585.
    • (2012) Psychoneuroendocrinology , vol.37 , Issue.4 , pp. 581-585
    • Darbra, S.1    Mòdol, L.2    Pallarès, M.3
  • 14
    • 3042708636 scopus 로고    scopus 로고
    • Age-related differences in elevated plus maze behavior between adolescent and adult rats
    • Doremus T.L., Varlinskaya E.I., Spear L.P. Age-related differences in elevated plus maze behavior between adolescent and adult rats. Ann. N.Y. Acad. Sci. 2004, 1021:427-430.
    • (2004) Ann. N.Y. Acad. Sci. , vol.1021 , pp. 427-430
    • Doremus, T.L.1    Varlinskaya, E.I.2    Spear, L.P.3
  • 15
    • 34548402661 scopus 로고    scopus 로고
    • The role of hippocampus in anxiety: intracerebral infusion sites
    • Engin E., Treit D. The role of hippocampus in anxiety: intracerebral infusion sites. Behav. Pharmacol. 2007, 18(5-6):365-374.
    • (2007) Behav. Pharmacol. , vol.18 , Issue.5-6 , pp. 365-374
    • Engin, E.1    Treit, D.2
  • 19
    • 71249129127 scopus 로고    scopus 로고
    • Neurosteroids' effects and mechanisms for social, cognitive, emotional, and physical functions
    • Frye C.A. Neurosteroids' effects and mechanisms for social, cognitive, emotional, and physical functions. Psychoneuroendocrinology 2009, 34(Suppl. 1):S143-S161.
    • (2009) Psychoneuroendocrinology , vol.34 , Issue.SUPPL. 1
    • Frye, C.A.1
  • 20
    • 0023233793 scopus 로고
    • GABA-dependent modulation of the Cl ionophore by steroids in rat brain
    • Gee K.W., Chang W.C., Brinton R.E., McEwen B.S. GABA-dependent modulation of the Cl ionophore by steroids in rat brain. Eur. J. Pharmacol. 1987, 136:419-423.
    • (1987) Eur. J. Pharmacol. , vol.136 , pp. 419-423
    • Gee, K.W.1    Chang, W.C.2    Brinton, R.E.3    McEwen, B.S.4
  • 21
    • 78049431667 scopus 로고    scopus 로고
    • Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats
    • George O., Vallée M., Vitiello S., Le Moalm M., Piazza P.V., Mayo W. Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats. Biol. Psychiatry 2010, 68(10):956-963.
    • (2010) Biol. Psychiatry , vol.68 , Issue.10 , pp. 956-963
    • George, O.1    Vallée, M.2    Vitiello, S.3    Le Moalm, M.4    Piazza, P.V.5    Mayo, W.6
  • 22
    • 2442562131 scopus 로고    scopus 로고
    • Neonatal neurosteroid administration alters parvalbumin expression and neuron number in medial dorsal thalamus of adult rats
    • Gizerian S.S., Morrow A.L., Lieberman J.A., Grobin A.C. Neonatal neurosteroid administration alters parvalbumin expression and neuron number in medial dorsal thalamus of adult rats. Brain Res. 2004, 1012:66-74.
    • (2004) Brain Res. , vol.1012 , pp. 66-74
    • Gizerian, S.S.1    Morrow, A.L.2    Lieberman, J.A.3    Grobin, A.C.4
  • 23
    • 33744472482 scopus 로고    scopus 로고
    • Neonatal neurosteroid administration results in development specific alterations in prepulse inhibition and locomotor activity: neurosteroids alter prepulse inhibition and locomotor activity
    • Gizerian S.S., Moy S.S., Lieberman J.A., Grobin A.C. Neonatal neurosteroid administration results in development specific alterations in prepulse inhibition and locomotor activity: neurosteroids alter prepulse inhibition and locomotor activity. Psychopharmacology (Berl.) 2006, 86:334-342.
    • (2006) Psychopharmacology (Berl.) , vol.86 , pp. 334-342
    • Gizerian, S.S.1    Moy, S.S.2    Lieberman, J.A.3    Grobin, A.C.4
  • 24
    • 0035955916 scopus 로고    scopus 로고
    • 3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex
    • Grobin A.C., Morrow A.L. 3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex. Brain Res. Dev. Brain Res. 2001, 131(1-2):31-39.
    • (2001) Brain Res. Dev. Brain Res. , vol.131 , Issue.1-2 , pp. 31-39
    • Grobin, A.C.1    Morrow, A.L.2
  • 25
    • 0037338155 scopus 로고    scopus 로고
    • Perinatal neurosteroid levels influence gabaergic interneuron localization in adult rat prefrontal cortex
    • Grobin A.C., Heenan E.J., Lieberman J.A., Morrow A.L. Perinatal neurosteroid levels influence gabaergic interneuron localization in adult rat prefrontal cortex. J. Neurosci. 2003, 23:1832-1839.
    • (2003) J. Neurosci. , vol.23 , pp. 1832-1839
    • Grobin, A.C.1    Heenan, E.J.2    Lieberman, J.A.3    Morrow, A.L.4
  • 26
    • 2942560999 scopus 로고    scopus 로고
    • Electrical stimulation of the hippocampus disrupts prepulse inhibition in rats: frequency and site-dependent effects
    • Howland J.G., MacKenzie E.M., Yim T.T., Taepavarapruk P., Phillips A.G. Electrical stimulation of the hippocampus disrupts prepulse inhibition in rats: frequency and site-dependent effects. Behav. Brain Res. 2004, 152(2):187-197.
    • (2004) Behav. Brain Res. , vol.152 , Issue.2 , pp. 187-197
    • Howland, J.G.1    MacKenzie, E.M.2    Yim, T.T.3    Taepavarapruk, P.4    Phillips, A.G.5
  • 27
    • 0037998929 scopus 로고    scopus 로고
    • Developmental expression of genes involved in neurosteroidogenesis: 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in the rat brain
    • Ibanez C., Guennoun R., Liere P., Eychenne B., Pianos A., El-Etr M., Baulieu E.E., Schumacher M. Developmental expression of genes involved in neurosteroidogenesis: 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in the rat brain. Endocrinology 2003, 144(7):2902-2911.
    • (2003) Endocrinology , vol.144 , Issue.7 , pp. 2902-2911
    • Ibanez, C.1    Guennoun, R.2    Liere, P.3    Eychenne, B.4    Pianos, A.5    El-Etr, M.6    Baulieu, E.E.7    Schumacher, M.8
  • 28
    • 0027257348 scopus 로고
    • On the role of the hippocampus in learning and memory in the rat
    • Jarrard L.E. On the role of the hippocampus in learning and memory in the rat. Behav. Neural Biol. 1993, 60(1):9-26.
    • (1993) Behav. Neural Biol. , vol.60 , Issue.1 , pp. 9-26
    • Jarrard, L.E.1
  • 29
    • 42149170120 scopus 로고    scopus 로고
    • Environmental novelty is signaled by reduction of the hippocampal theta frequency
    • Jeewajee A., Lever C., Burton S., O'Keefe J., Burgess N. Environmental novelty is signaled by reduction of the hippocampal theta frequency. Hippocampus 2008, 18(340):348.
    • (2008) Hippocampus , vol.18 , Issue.340 , pp. 348
    • Jeewajee, A.1    Lever, C.2    Burton, S.3    O'Keefe, J.4    Burgess, N.5
  • 30
    • 0038069379 scopus 로고    scopus 로고
    • Risktaking behavior in adolescent mice: psychobiological determinants and early epigenetic influence
    • Laviola G., Macri S., Morley-Fletcher S., Adriani W. Risktaking behavior in adolescent mice: psychobiological determinants and early epigenetic influence. Neurosci. Biobehav. Rev. 2003, 27:19-31.
    • (2003) Neurosci. Biobehav. Rev. , vol.27 , pp. 19-31
    • Laviola, G.1    Macri, S.2    Morley-Fletcher, S.3    Adriani, W.4
  • 31
    • 27744546607 scopus 로고    scopus 로고
    • The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine
    • Martin-Garcia E., Pallares M. The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine. Brain Res. 2005, 1062(1-2):144-150.
    • (2005) Brain Res. , vol.1062 , Issue.1-2 , pp. 144-150
    • Martin-Garcia, E.1    Pallares, M.2
  • 32
    • 0034332492 scopus 로고    scopus 로고
    • Neuronal activity and brain-derived neurotrophic factor regulate the density of inhibitory synapses in organotypic slice cultures of postnatal hippocampus
    • Marty S., Wehrlé R., Sotelo C. Neuronal activity and brain-derived neurotrophic factor regulate the density of inhibitory synapses in organotypic slice cultures of postnatal hippocampus. J. Neurosci. 2000, 20:8087-8095.
    • (2000) J. Neurosci. , vol.20 , pp. 8087-8095
    • Marty, S.1    Wehrlé, R.2    Sotelo, C.3
  • 33
    • 0027394538 scopus 로고
    • Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat
    • Mayo W., Dellu F., Robel P., Cherkaoui J., Le Moal M., Baulieu E.E. Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat. Brain Res. 1993, 607:324-328.
    • (1993) Brain Res. , vol.607 , pp. 324-328
    • Mayo, W.1    Dellu, F.2    Robel, P.3    Cherkaoui, J.4    Le Moal, M.5    Baulieu, E.E.6
  • 34
    • 34548563903 scopus 로고    scopus 로고
    • Neurosteroid regulation of central nervous system development
    • Mellon S.H. Neurosteroid regulation of central nervous system development. Pharmacol. Ther. 2007, 116(1):107-124.
    • (2007) Pharmacol. Ther. , vol.116 , Issue.1 , pp. 107-124
    • Mellon, S.H.1
  • 35
    • 79954604495 scopus 로고    scopus 로고
    • Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning
    • Mòdol L., Darbra S., Pallarès M. Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning. Behav. Brain Res. 2011, 222(1):223-229.
    • (2011) Behav. Brain Res. , vol.222 , Issue.1 , pp. 223-229
    • Mòdol, L.1    Darbra, S.2    Pallarès, M.3
  • 36
    • 84878662362 scopus 로고    scopus 로고
    • Alterations of allopreganolone levels affects alfa 4 and delta GABA A subunit expression and adult behavioural hippocampal response to neurosteroids. FENS Forum Abstr., A-471-0184-01765.
    • Mòdol, L., Llidó, A., Casas, C., Navarro, X., Pallares, M., Darbra, S., 2012. Alterations of allopreganolone levels affects alfa 4 and delta GABA A subunit expression and adult behavioural hippocampal response to neurosteroids. FENS Forum Abstr., A-471-0184-01765.
    • (2012)
    • Mòdol, L.1    Llidó, A.2    Casas, C.3    Navarro, X.4    Pallares, M.5    Darbra, S.6
  • 37
    • 0037466765 scopus 로고    scopus 로고
    • Increased neurosteroid sensitivity of hippocampal GABAa receptors during postnatal development
    • Mtchedlishvili Z., Sun C.S., Harrison M.B., Kapur J. Increased neurosteroid sensitivity of hippocampal GABAa receptors during postnatal development. Neuroscience 2003, 118:655-666.
    • (2003) Neuroscience , vol.118 , pp. 655-666
    • Mtchedlishvili, Z.1    Sun, C.S.2    Harrison, M.B.3    Kapur, J.4
  • 38
    • 51449117376 scopus 로고    scopus 로고
    • Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolism
    • Mukai Y., Higashin T., Nagura Y., Shimada K. Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolism. Biol. Pharm. Bull. 2008, 31(9):1646-1650.
    • (2008) Biol. Pharm. Bull. , vol.31 , Issue.9 , pp. 1646-1650
    • Mukai, Y.1    Higashin, T.2    Nagura, Y.3    Shimada, K.4
  • 39
    • 0036098149 scopus 로고    scopus 로고
    • A neuroactive steroid, pregnenolone, alters the striatal dopaminergic tone before and after puberty
    • Muneoka K., Takigawa T.M. A neuroactive steroid, pregnenolone, alters the striatal dopaminergic tone before and after puberty. Neuroendocrinology 2002, 75:288-295.
    • (2002) Neuroendocrinology , vol.75 , pp. 288-295
    • Muneoka, K.1    Takigawa, T.M.2
  • 40
    • 0032483112 scopus 로고    scopus 로고
    • The neurosteroid pregnenolone sulfate infused into the nucleus basalis increases both acetylcholine release in the frontal cortex or amygdala and spatial memory
    • Pallares M., Darnaudery M., Day J., Le Moal M., Mayo W. The neurosteroid pregnenolone sulfate infused into the nucleus basalis increases both acetylcholine release in the frontal cortex or amygdala and spatial memory. Neuroscience 1998, 87:551-558.
    • (1998) Neuroscience , vol.87 , pp. 551-558
    • Pallares, M.1    Darnaudery, M.2    Day, J.3    Le Moal, M.4    Mayo, W.5
  • 42
    • 0031594582 scopus 로고    scopus 로고
    • Transient expression of the 5alpha-reductase type 2 isozyme in the rat brain in late fetal and early postnatal life
    • Poletti A., Negri-Cesi P., Rabuffetti M., Colciago A., Celotti F., Martini L. Transient expression of the 5alpha-reductase type 2 isozyme in the rat brain in late fetal and early postnatal life. Endocrinology 1998, 139(4):2171-2178.
    • (1998) Endocrinology , vol.139 , Issue.4 , pp. 2171-2178
    • Poletti, A.1    Negri-Cesi, P.2    Rabuffetti, M.3    Colciago, A.4    Celotti, F.5    Martini, L.6
  • 43
    • 18644384781 scopus 로고    scopus 로고
    • Trophic actions of GABA on neuronal development
    • Represa A., Ben-Ari Y. Trophic actions of GABA on neuronal development. Trends Neurosci. 2005, 28(6):278-283.
    • (2005) Trends Neurosci. , vol.28 , Issue.6 , pp. 278-283
    • Represa, A.1    Ben-Ari, Y.2
  • 45
    • 0028173882 scopus 로고
    • Steroid 5a-reductase: two genes/two enzymes
    • Russell D.W., Wilson J.D. Steroid 5a-reductase: two genes/two enzymes. Annu. Rev. Biochem. 1994, 63:25-61.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 25-61
    • Russell, D.W.1    Wilson, J.D.2
  • 46
    • 33749514264 scopus 로고    scopus 로고
    • Effects of testosterone on brain mRNA levels of steroid 5alpha-reductase isozymes in early postnatal life of rat
    • Sánchez P., Torres J.M., Del Moral R.G., Ortega E. Effects of testosterone on brain mRNA levels of steroid 5alpha-reductase isozymes in early postnatal life of rat. Neurochem. Int. 2006, 49(6):626-630.
    • (2006) Neurochem. Int. , vol.49 , Issue.6 , pp. 626-630
    • Sánchez, P.1    Torres, J.M.2    Del Moral, R.G.3    Ortega, E.4
  • 47
    • 0036231790 scopus 로고    scopus 로고
    • Withdrawal properties of a neuroactive steroid: implication for GABAA receptor gene regulation in the brain and anxiety behavior
    • Smith S.S. Withdrawal properties of a neuroactive steroid: implication for GABAA receptor gene regulation in the brain and anxiety behavior. Steroids 2002, 67:519-528.
    • (2002) Steroids , vol.67 , pp. 519-528
    • Smith, S.S.1
  • 48
    • 33845325470 scopus 로고    scopus 로고
    • Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function
    • Swerdlow N.R., Light G.A., Cadenhead K.S., Sprock J., Hsieh M.H., Braff D.L. Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function. Arch. Gen. Psychiatry 2006, 63(12):1325-1335.
    • (2006) Arch. Gen. Psychiatry , vol.63 , Issue.12 , pp. 1325-1335
    • Swerdlow, N.R.1    Light, G.A.2    Cadenhead, K.S.3    Sprock, J.4    Hsieh, M.H.5    Braff, D.L.6
  • 49
    • 0032577475 scopus 로고    scopus 로고
    • Changes in head-dipping behavior in the holeboard test reflect the anxiogenic and/or anxiolytic state in mice
    • Takeda H., Tsuji M., Matsumiya T. Changes in head-dipping behavior in the holeboard test reflect the anxiogenic and/or anxiolytic state in mice. Eur. J. Pharmacol. 1998, 350(1):21-29.
    • (1998) Eur. J. Pharmacol. , vol.350 , Issue.1 , pp. 21-29
    • Takeda, H.1    Tsuji, M.2    Matsumiya, T.3
  • 50
    • 0021806827 scopus 로고
    • Animal models for the study of anti-anxiety agents: a review
    • Treit D. Animal models for the study of anti-anxiety agents: a review. Neurosci. Biobehav. Rev. 1985, 9(2):203-222.
    • (1985) Neurosci. Biobehav. Rev. , vol.9 , Issue.2 , pp. 203-222
    • Treit, D.1
  • 52
    • 0034544581 scopus 로고    scopus 로고
    • Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry
    • Vallée M., Rivera J.D., Koob G.F., Purdy R.H., Fitzgerald R.L. Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry. Anal. Biochem. 2000, 287:153-166.
    • (2000) Anal. Biochem. , vol.287 , pp. 153-166
    • Vallée, M.1    Rivera, J.D.2    Koob, G.F.3    Purdy, R.H.4    Fitzgerald, R.L.5
  • 53
    • 18644371723 scopus 로고    scopus 로고
    • The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression
    • Wang J.M., Johnston P.B., Ball B.G., Brinton R.D. The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression. J. Neurosci. 2005, 25(19):4706-4718.
    • (2005) J. Neurosci. , vol.25 , Issue.19 , pp. 4706-4718
    • Wang, J.M.1    Johnston, P.B.2    Ball, B.G.3    Brinton, R.D.4
  • 54
    • 0036846534 scopus 로고    scopus 로고
    • Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients
    • Weill-Engerer S., David J.P., Sazdovitch V., Liere P., Eychenne B., Pianos A., et al. Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients. J. Clin. Endocrinol. Metab. 2002, 87(11):5138-5143.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , Issue.11 , pp. 5138-5143
    • Weill-Engerer, S.1    David, J.P.2    Sazdovitch, V.3    Liere, P.4    Eychenne, B.5    Pianos, A.6
  • 55
    • 70149108055 scopus 로고    scopus 로고
    • Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain
    • Yawno T., Hirst J.J., Castillo-Melendez M., Walker D.W. Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain. Neuroscience 2009, 163(3):838-847.
    • (2009) Neuroscience , vol.163 , Issue.3 , pp. 838-847
    • Yawno, T.1    Hirst, J.J.2    Castillo-Melendez, M.3    Walker, D.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.