The correlation between dose of folinic acid and neurotoxicity in children and adolescents treated for osteosarcoma with high-dose methotrexate (HDMTX): A neuropsychological and psychosocial study

Journal of Pediatric Hematology/Oncology

Volumn 35, Issue 4, 2013, Pages 271-275

  Bonda Shkedi, Esther ^a,b   Arush, Myriam Weyl Ben ^c   Kaplinsky, Chaim ^d,e   Ash, Shifra ^a,e   Goshen, Yaakov ^a,e   Yaniv, Isaac ^a,e   Cohen, Ian J ^a,e  

^a SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c MEYER CHILDREN S HOSPITAL   (Israel)

^d SHEBA MEDICAL CENTER   (Israel)

^e TEL AVIV UNIVERSITY   (Israel)

Author keywords

Folinic acid; Methotrexate; Neuropsychology; Neurotoxicity; Prevention

Indexed keywords

FOLINIC ACID; METHOTREXATE; ANTINEOPLASTIC ANTIMETABOLITE;

ADOLESCENT; ADULT; ARTICLE; ATTENTION; CHILD; CLINICAL ARTICLE; CLINICAL PROTOCOL; COMPREHENSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; EXECUTIVE FUNCTION; FEMALE; HUMAN; LOW DRUG DOSE; MALE; MENTAL HEALTH; NEUROPSYCHOLOGY; NEUROTOXICITY; OSTEOSARCOMA; PRIORITY JOURNAL; QUALITY OF LIFE; SCHOOL CHILD; SELF ESTEEM; SOCIAL PSYCHOLOGY; SOCIAL STATUS; SOCIAL SUPPORT; TREATMENT DURATION; TREATMENT RESPONSE; VERBAL MEMORY; VISION; VISUAL MEMORY; BONE TUMOR; NEUROPSYCHOLOGICAL TEST; PSYCHOLOGICAL ASPECT; TOXICITY AND INTOXICATION;

ADOLESCENT; ADULT; ANTIMETABOLITES, ANTINEOPLASTIC; BONE NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LEUCOVORIN; MALE; METHOTREXATE; NEUROPSYCHOLOGICAL TESTS; NEUROTOXICITY SYNDROMES; OSTEOSARCOMA; YOUNG ADULT;

MLCS; MLOWN;

EID: 84878637282     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e31828c2da1     Document Type: Article

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