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Volumn 14, Issue 10, 1996, Pages 2803-2811

Intensive oral methotrexate protects against lymphoid marrow relapse in childhood B-precursor acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; FOLINIC ACID; MERCAPTOPURINE; METHOTREXATE; PREDNISONE; VINCRISTINE;

EID: 0029739087     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1996.14.10.2803     Document Type: Article
Times cited : (47)

References (53)
  • 1
    • 78651010566 scopus 로고
    • Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid (aminopterin)
    • Farber S, Diamond LK, Mercer RD, et al: Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid (aminopterin). N Engl J Med 238:787-793, 1948
    • (1948) N Engl J Med , vol.238 , pp. 787-793
    • Farber, S.1    Diamond, L.K.2    Mercer, R.D.3
  • 2
    • 0026563349 scopus 로고
    • Impact of three methods of treatment intensification on acute lymphoblastic leukemia in children: Long-term results of St. Jude total therapy study X
    • Pui CH, Simone JV, Hancock ML, et al: Impact of three methods of treatment intensification on acute lymphoblastic leukemia in children: Long-term results of St. Jude total therapy study X. Leukemia 6:150-157, 1992
    • (1992) Leukemia , vol.6 , pp. 150-157
    • Pui, C.H.1    Simone, J.V.2    Hancock, M.L.3
  • 3
    • 0027514199 scopus 로고
    • Intensive alternating drug pairs for treatment of high-risk childhood acute lymphoblastic leukemia
    • Lauer SJ, Camitta BM, Leventhal BG, et al: Intensive alternating drug pairs for treatment of high-risk childhood acute lymphoblastic leukemia. Cancer 71:2854-2861, 1993
    • (1993) Cancer , vol.71 , pp. 2854-2861
    • Lauer, S.J.1    Camitta, B.M.2    Leventhal, B.G.3
  • 4
    • 0028365137 scopus 로고
    • Intensive intravenous methotrexate and mercaptopurine treatment of higher-risk non-T acute lymphocytic leukemia
    • Camitta B, Mahoney D, Leventhal B, et al: Intensive intravenous methotrexate and mercaptopurine treatment of higher-risk non-T acute lymphocytic leukemia. J Clin Oncol 12:1383-1389, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 1383-1389
    • Camitta, B.1    Mahoney, D.2    Leventhal, B.3
  • 5
    • 0028037399 scopus 로고
    • Comparison of two schedules of intermediate-dose methotrexate and cytarabine consolidation therapy for childhood B-precursor cell acute lymphoblastic leukemia
    • Land VJ, Shuster JJ, Crist WM, et al: Comparison of two schedules of intermediate-dose methotrexate and cytarabine consolidation therapy for childhood B-precursor cell acute lymphoblastic leukemia. J Clin Oncol 12:1939-1945, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 1939-1945
    • Land, V.J.1    Shuster, J.J.2    Crist, W.M.3
  • 6
    • 0028204905 scopus 로고
    • Treatment of childhood acute lymphoblastic leukemia
    • Schorin MA, Blattner S, Gelber RD, et al: Treatment of childhood acute lymphoblastic leukemia. J Clin Oncol 12:740-747, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 740-747
    • Schorin, M.A.1    Blattner, S.2    Gelber, R.D.3
  • 7
    • 0028152851 scopus 로고
    • Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86
    • Reiter A, Schrappe M, Ludwig W-D, et al: Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86. Blood 84:3122-3133, 1994
    • (1994) Blood , vol.84 , pp. 3122-3133
    • Reiter, A.1    Schrappe, M.2    Ludwig, W.-D.3
  • 8
    • 0028937496 scopus 로고
    • Clinical resistance to antimetabolites
    • Spears CP: Clinical resistance to antimetabolites. Hematol Oncol Clin North Am 9:397-413, 1995
    • (1995) Hematol Oncol Clin North Am , vol.9 , pp. 397-413
    • Spears, C.P.1
  • 9
    • 0019957257 scopus 로고
    • Relationship of pretreatment lymphoblast proliferative activity and prognosis in 97 children with acute lymphoblastic leukemia
    • Dow LW, Chang LJ, Tsiatis AA, et al: Relationship of pretreatment lymphoblast proliferative activity and prognosis in 97 children with acute lymphoblastic leukemia. Blood 59:1197-1202, 1982
    • (1982) Blood , vol.59 , pp. 1197-1202
    • Dow, L.W.1    Chang, L.J.2    Tsiatis, A.A.3
  • 10
    • 0019914176 scopus 로고
    • Aneuploidy and percentage of S-phase cells determined by flow cytometry correlate with cell phenotype in childhood acute leukemia
    • Look AT, Melvin SL, Williams DL, et al: Aneuploidy and percentage of S-phase cells determined by flow cytometry correlate with cell phenotype in childhood acute leukemia. Blood 60:959-967, 1982
    • (1982) Blood , vol.60 , pp. 959-967
    • Look, A.T.1    Melvin, S.L.2    Williams, D.L.3
  • 11
    • 0020436668 scopus 로고
    • Determination of the significance of in vitro blast cell [3H] thymidine labelling indices obtained initially and serially during induction therapy of acute non-lymphocytic leukemia
    • Murphy SB, Dahl GV, George SL, et al: Determination of the significance of in vitro blast cell [3H] thymidine labelling indices obtained initially and serially during induction therapy of acute non-lymphocytic leukemia. Leuk Res 6:639-648, 1982
    • (1982) Leuk Res , vol.6 , pp. 639-648
    • Murphy, S.B.1    Dahl, G.V.2    George, S.L.3
  • 12
    • 0023914950 scopus 로고
    • Effects of methotrexate on purine and pyrimidine metabolism and cell kinetic parameters in human malignant lymphoblasts of different lineages
    • Bokkerink JA, Ronney A: Effects of methotrexate on purine and pyrimidine metabolism and cell kinetic parameters in human malignant lymphoblasts of different lineages. Biochem Pharmacol 37:2329-2338. 1988
    • (1988) Biochem Pharmacol , vol.37 , pp. 2329-2338
    • Bokkerink, J.A.1    Ronney, A.2
  • 13
    • 0022350968 scopus 로고
    • Maintenance chemotherapy for childhood acute lymphoblastic leukemia: Better in the evening
    • Rivard GE, Infante-Rivard C, Hoyoux C, et al: Maintenance chemotherapy for childhood acute lymphoblastic leukemia: Better in the evening. Lancet 2:1264-1266, 1985
    • (1985) Lancet , vol.2 , pp. 1264-1266
    • Rivard, G.E.1    Infante-Rivard, C.2    Hoyoux, C.3
  • 14
    • 0001160855 scopus 로고
    • Schedule dependent synergism and antagonism between methotrexate and asparaginase
    • Capizzi RL: Schedule dependent synergism and antagonism between methotrexate and asparaginase. Biochem Pharmacol 23:151-161, 1974
    • (1974) Biochem Pharmacol , vol.23 , pp. 151-161
    • Capizzi, R.L.1
  • 15
    • 0016810643 scopus 로고
    • Improvement in the therapeutic index of metho trexate (NSC-740) by L-asparaginase (NSC-109229)
    • Capizzi R: Improvement in the therapeutic index of metho trexate (NSC-740) by L-asparaginase (NSC-109229). Cancer Che-mother Rep 6:37-41, 1975
    • (1975) Cancer Che-mother Rep , vol.6 , pp. 37-41
    • Capizzi, R.1
  • 16
    • 0018941279 scopus 로고
    • Methotrexate-L-aspara-ginase combination chemotherapy for patients with acute leukemia in relapse: A study of 36 children
    • Harris RE, McCallister JA, Provisor DS: Methotrexate-L-aspara-ginase combination chemotherapy for patients with acute leukemia in relapse: A study of 36 children. Cancer 46:2004-2008, 1980
    • (1980) Cancer , vol.46 , pp. 2004-2008
    • Harris, R.E.1    McCallister, J.A.2    Provisor, D.S.3
  • 17
    • 0019763549 scopus 로고
    • Asparaginase-methotrexate in combination chemotherapy. Schedule-dependent differential effects on normal versus neoplastic cells
    • Capizzi RL: Asparaginase-methotrexate in combination chemotherapy. Schedule-dependent differential effects on normal versus neoplastic cells. Cancer Treat Rep 65:115-120, 1981
    • (1981) Cancer Treat Rep , vol.65 , pp. 115-120
    • Capizzi, R.L.1
  • 18
    • 0017162163 scopus 로고
    • Proposals for the classification of the acute leukemias
    • Bennett JM, Catovsky D, Daniel MT: Proposals for the classification of the acute leukemias. Br J Haematol 33:451-458, 1976
    • (1976) Br J Haematol , vol.33 , pp. 451-458
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3
  • 19
    • 0025192778 scopus 로고
    • Myeloid-associated antigen expression lacks prognostic value in childhood acute lymphoblastic leukemia treated with intensive multiagent chemotherapy
    • Pui CH, Behm FG, Singh B: Myeloid-associated antigen expression lacks prognostic value in childhood acute lymphoblastic leukemia treated with intensive multiagent chemotherapy. Blood 75:198-202, 1990
    • (1990) Blood , vol.75 , pp. 198-202
    • Pui, C.H.1    Behm, F.G.2    Singh, B.3
  • 20
    • 0025143234 scopus 로고
    • Prognostic significance of CD34 expression in childhood B-precursor acute lymphocytic leukemia
    • Borowitz MJ, Shuster JJ, Civin CI: Prognostic significance of CD34 expression in childhood B-precursor acute lymphocytic leukemia. J Clin Oncol 8:1389-1398, 1990
    • (1990) J Clin Oncol , vol.8 , pp. 1389-1398
    • Borowitz, M.J.1    Shuster, J.J.2    Civin, C.I.3
  • 21
    • 0026525903 scopus 로고
    • Unexpected acute neurologic toxicity in children with acute lymphoblastic leukemia receiving intensive oral methotrexate
    • Winick N, Bowman WP, Kamen BA, et al: Unexpected acute neurologic toxicity in children with acute lymphoblastic leukemia receiving intensive oral methotrexate. J Natl Cancer Inst 84:252-256, 1992
    • (1992) J Natl Cancer Inst , vol.84 , pp. 252-256
    • Winick, N.1    Bowman, W.P.2    Kamen, B.A.3
  • 22
    • 0028012494 scopus 로고
    • Aerosolized pentamidine for the prevention of pneumocystic carinii pneumonia in children with cancer intolerant or allergic to trimethoprim/sulfamethoxazole
    • Mustafa MM, Pappo A, Cash J, et al: Aerosolized pentamidine for the prevention of pneumocystic carinii pneumonia in children with cancer intolerant or allergic to trimethoprim/sulfamethoxazole. J Clin Oncol 12:258-261, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 258-261
    • Mustafa, M.M.1    Pappo, A.2    Cash, J.3
  • 23
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 24
    • 0017365573 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observation of each patient
    • Peto R, Pike MC, Armitage P: Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Br J Cancer 35:1-39, 1977
    • (1977) Br J Cancer , vol.35 , pp. 1-39
    • Peto, R.1    Pike, M.C.2    Armitage, P.3
  • 25
    • 0021284337 scopus 로고
    • Pediatric Oncology Group utilization of immunologic markers in the designation of acute lymphocytic leukemia (ALL) subgroups. Influence on treatment response
    • Pullen DJ, Boyett JM, Crist WM: Pediatric Oncology Group utilization of immunologic markers in the designation of acute lymphocytic leukemia (ALL) subgroups. Influence on treatment response. Ann N Y Acad Sci 428:26-48. 1984
    • (1984) Ann N Y Acad Sci , vol.428 , pp. 26-48
    • Pullen, D.J.1    Boyett, J.M.2    Crist, W.M.3
  • 26
    • 0027403501 scopus 로고
    • Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide
    • Winick N, McKenna RW, Shuster JJ: Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide. J Clin Oncol 11:209-217, 1993
    • (1993) J Clin Oncol , vol.11 , pp. 209-217
    • Winick, N.1    McKenna, R.W.2    Shuster, J.J.3
  • 27
    • 0344048974 scopus 로고
    • Prolonged intensive oral methotrexate does not induce its own malabsorption
    • Winick N, Bowman W, Arencibia-Mireles O, et al: Prolonged intensive oral methotrexate does not induce its own malabsorption. Cancer Chemother Control 1:245-250, 1990
    • (1990) Cancer Chemother Control , vol.1 , pp. 245-250
    • Winick, N.1    Bowman, W.2    Arencibia-Mireles, O.3
  • 28
    • 0020680188 scopus 로고
    • Comparison of inter-mediate-dose methotrexate with cranial irradiation for the post-induction treatment of acute lymphoblastic leukemia in children
    • Freeman AI, Weinberg V, Brecher ML: Comparison of inter-mediate-dose methotrexate with cranial irradiation for the post-induction treatment of acute lymphoblastic leukemia in children. N Engl J Med 308:477-484, 1983
    • (1983) N Engl J Med , vol.308 , pp. 477-484
    • Freeman, A.I.1    Weinberg, V.2    Brecher, M.L.3
  • 29
    • 0020404318 scopus 로고
    • The use of intermediate-dose methotrexate in increased risk childhood acute lymphoblastic leukemia. A comparison of three vs. six courses
    • Green DM, Brecher ML, Blumenson LE: The use of intermediate-dose methotrexate in increased risk childhood acute lymphoblastic leukemia. A comparison of three vs. six courses. Cancer 50:2722-2727, 1982
    • (1982) Cancer , vol.50 , pp. 2722-2727
    • Green, D.M.1    Brecher, M.L.2    Blumenson, L.E.3
  • 30
    • 0023462652 scopus 로고
    • New aspects of clinical and cellular pharmacodynamics of methotrexate with special emphasis on its role in the treatment of acute lymphoblastic leukemia in children
    • Borsi JD, Moe PJ: New aspects of clinical and cellular pharmacodynamics of methotrexate with special emphasis on its role in the treatment of acute lymphoblastic leukemia in children. Acta Paediatr Scand 341:1-31, 1987 (suppl)
    • (1987) Acta Paediatr Scand , vol.341 , Issue.SUPPL. , pp. 1-31
    • Borsi, J.D.1    Moe, P.J.2
  • 31
    • 0023944389 scopus 로고
    • Efficacy of high-dose methotrexate in childhood acute lymphoblastic leukemia: Analysis by contemporary risk classification
    • Abromowitch M, Ochs J, Pui CH: Efficacy of high-dose methotrexate in childhood acute lymphoblastic leukemia: Analysis by contemporary risk classification. Blood 71:866-869, 1988
    • (1988) Blood , vol.71 , pp. 866-869
    • Abromowitch, M.1    Ochs, J.2    Pui, C.H.3
  • 32
    • 0023508521 scopus 로고
    • Systemic clearance of methotrexate in the prognosis of acute lymphoblastic leukemia in children
    • Borsi JD, Moe PJ: Systemic clearance of methotrexate in the prognosis of acute lymphoblastic leukemia in children. Cancer 60:3020-3024, 1987
    • (1987) Cancer , vol.60 , pp. 3020-3024
    • Borsi, J.D.1    Moe, P.J.2
  • 33
    • 0023924833 scopus 로고
    • High-dose methotrexate: Insecure rationale
    • Kamen BA, Winick NJ: High-dose methotrexate: Insecure rationale. Biochem Pharmacol 37:2713-2715, 1988
    • (1988) Biochem Pharmacol , vol.37 , pp. 2713-2715
    • Kamen, B.A.1    Winick, N.J.2
  • 34
    • 0027267433 scopus 로고
    • Randomized comparison of 36-hour intermediate-dose versus 4-hour high-dose methotrexate infusions for remission induction in relapsed childhood acute lymphoblastic leukemia
    • Wolfrom C, Hartmann R, Fengler R, et al: Randomized comparison of 36-hour intermediate-dose versus 4-hour high-dose methotrexate infusions for remission induction in relapsed childhood acute lymphoblastic leukemia. J Clin Oncol 11:827-833, 1993
    • (1993) J Clin Oncol , vol.11 , pp. 827-833
    • Wolfrom, C.1    Hartmann, R.2    Fengler, R.3
  • 35
    • 0010514872 scopus 로고
    • Therapy of neoplasia with asparaginase
    • Holcenberg J, Roberts J (eds): New York, NY, Wiley
    • Capizzi R, Cheng Y: Therapy of neoplasia with asparaginase, in Holcenberg J, Roberts J (eds): Enzymes as Drugs. New York, NY, Wiley, 1981, pp 1-24
    • (1981) Enzymes as Drugs , pp. 1-24
    • Capizzi, R.1    Cheng, Y.2
  • 36
    • 0022007010 scopus 로고
    • Prevention of methotrexate cytotoxicity by asparaginase inhibition of methotrexate polyglutamate formation
    • Jolivet J, Cole DE, Holcenberg JS, et al: Prevention of methotrexate cytotoxicity by asparaginase inhibition of methotrexate polyglutamate formation. Cancer Res 45:217-220, 1985
    • (1985) Cancer Res , vol.45 , pp. 217-220
    • Jolivet, J.1    Cole, D.E.2    Holcenberg, J.S.3
  • 37
    • 0018750104 scopus 로고
    • Methotrexate and asparaginase combination chemotherapy in refractory acute lymphoblastic leukemia in childhood
    • Lobel J, O'Brien R, McIntosh S: Methotrexate and asparaginase combination chemotherapy in refractory acute lymphoblastic leukemia in childhood. Cancer 43:1089-1094, 1979
    • (1979) Cancer , vol.43 , pp. 1089-1094
    • Lobel, J.1    O'Brien, R.2    McIntosh, S.3
  • 38
    • 0019834138 scopus 로고
    • Asparaginase and methotrexate combination chemotherapy in relapsed acute lymphoblastic leukemia in adults
    • Yap B, McCredie KB, Keating MJ: Asparaginase and methotrexate combination chemotherapy in relapsed acute lymphoblastic leukemia in adults. Cancer Treat Rep 65:83-87, 1981
    • (1981) Cancer Treat Rep , vol.65 , pp. 83-87
    • Yap, B.1    McCredie, K.B.2    Keating, M.J.3
  • 39
    • 0028063423 scopus 로고
    • Blast cell methotrexate - Polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia
    • Snyold TW, Relling MV, Boyett JM, et al: Blast cell methotrexate - Polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia. J Clin Invest 94:1996-2001, 1994
    • (1994) J Clin Invest , vol.94 , pp. 1996-2001
    • Snyold, T.W.1    Relling, M.V.2    Boyett, J.M.3
  • 40
    • 0017839684 scopus 로고
    • Optimization of high-dose methotrexate with leucovorin rescue therapy in the L1210 leukemia and sarcoma 180 murine tumor models
    • Sirotnak FM, Moccio DM, Dorick DM: Optimization of high-dose methotrexate with leucovorin rescue therapy in the L1210 leukemia and sarcoma 180 murine tumor models. Cancer Res 38:345-353, 1978
    • (1978) Cancer Res , vol.38 , pp. 345-353
    • Sirotnak, F.M.1    Moccio, D.M.2    Dorick, D.M.3
  • 41
    • 0025020239 scopus 로고
    • Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: A randomized placebo-controlled clinical trial
    • Browman GP, Goodyear MDE, Levine MN, et al: Modulation of the antitumor effect of methotrexate by low-dose leucovorin in squamous cell head and neck cancer: A randomized placebo-controlled clinical trial. J Clin Oncol 8:203-208, 1990
    • (1990) J Clin Oncol , vol.8 , pp. 203-208
    • Browman, G.P.1    Goodyear, M.D.E.2    Levine, M.N.3
  • 42
    • 0024544745 scopus 로고
    • Evidence for CSF accumulation of 5-methyltetrahydrofolate during repeated courses of methotrexate plus folinic acid rescue
    • Thyss A, Milano G, Etienne MC, et al: Evidence for CSF accumulation of 5-methyltetrahydrofolate during repeated courses of methotrexate plus folinic acid rescue. Br J Cancer 59:627-630, 1989
    • (1989) Br J Cancer , vol.59 , pp. 627-630
    • Thyss, A.1    Milano, G.2    Etienne, M.C.3
  • 43
    • 20244372361 scopus 로고
    • Evidence for CSF accumulation of 5-methyltetrahydrofolate during repeated courses of methotrexate plus folinic acid rescue
    • letter
    • Kamen BA, Vietti T: Evidence for CSF accumulation of 5-methyltetrahydrofolate during repeated courses of methotrexate plus folinic acid rescue. Br J Cancer 60:799, 1989 (letter)
    • (1989) Br J Cancer , vol.60 , pp. 799
    • Kamen, B.A.1    Vietti, T.2
  • 44
    • 0021268738 scopus 로고
    • Pharmacokinetics of the diastereoisomers of leucovorin after intravenous and oral administration to normal subjects
    • Straw JA, Szapary D, Wynn WT: Pharmacokinetics of the diastereoisomers of leucovorin after intravenous and oral administration to normal subjects. Cancer Res 44:3114-3119, 1984
    • (1984) Cancer Res , vol.44 , pp. 3114-3119
    • Straw, J.A.1    Szapary, D.2    Wynn, W.T.3
  • 45
    • 0023515018 scopus 로고
    • Pharmacokinetics of leucovorin (D,L-5-formyltetrahydrofolate) after intravenous injection and constant intravenous infusion
    • Straw JA, Newman EM, Doroshow JH: Pharmacokinetics of leucovorin (D,L-5-formyltetrahydrofolate) after intravenous injection and constant intravenous infusion. NCI Monogr 5:41-45, 1987
    • (1987) NCI Monogr , vol.5 , pp. 41-45
    • Straw, J.A.1    Newman, E.M.2    Doroshow, J.H.3
  • 46
    • 0025789017 scopus 로고
    • How much is too much? Folinic acid rescue dose in children with acute lymphoblastic leukaemia
    • Borsi JD, Wesenberg F, Stokland T, et al: How much is too much? Folinic acid rescue dose in children with acute lymphoblastic leukaemia. Eur J Cancer 27:1006-1009, 1991
    • (1991) Eur J Cancer , vol.27 , pp. 1006-1009
    • Borsi, J.D.1    Wesenberg, F.2    Stokland, T.3
  • 47
    • 0026079804 scopus 로고
    • Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia
    • Pui CH, Ribeiro RC, Hancock ML: Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia. N Engl J Med 325:1682-1687, 1991
    • (1991) N Engl J Med , vol.325 , pp. 1682-1687
    • Pui, C.H.1    Ribeiro, R.C.2    Hancock, M.L.3
  • 48
    • 0024004497 scopus 로고
    • Increase in etoposide-induced topoisomerase H-mediated DNA breaks after cell synchronization induced by low doses of methotrexate
    • Lorico A, Rappa G, Boiocchi M: Increase in etoposide-induced topoisomerase H-mediated DNA breaks after cell synchronization induced by low doses of methotrexate. Biochem Pharmacol 37:1883-1884, 1988
    • (1988) Biochem Pharmacol , vol.37 , pp. 1883-1884
    • Lorico, A.1    Rappa, G.2    Boiocchi, M.3
  • 49
    • 0028997908 scopus 로고
    • Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo
    • Holden SA, Teicher BA, Robinson MF, et al: Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo. Cancer Chemother Pharmacol 36:165-171, 1995
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 165-171
    • Holden, S.A.1    Teicher, B.A.2    Robinson, M.F.3
  • 50
    • 0028973397 scopus 로고
    • L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxins
    • Pui CH, Relling MV, Behm FG, et al: L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxins. Leukemia 9:1680-1684, 1995
    • (1995) Leukemia , vol.9 , pp. 1680-1684
    • Pui, C.H.1    Relling, M.V.2    Behm, F.G.3
  • 51
    • 0027300253 scopus 로고
    • Secondary acute myeloid leukemia in Hispanic children
    • letter
    • Winick N, Buchanan GR, Kamen BA: Secondary acute myeloid leukemia in Hispanic children. J Clin Oncol 11:1433, 1993 (letter)
    • (1993) J Clin Oncol , vol.11 , pp. 1433
    • Winick, N.1    Buchanan, G.R.2    Kamen, B.A.3
  • 52
    • 0028775357 scopus 로고
    • Infant leukemia, topoisomerase II inhibitors, and the MLL gene
    • Ross JA, Potter JD, Robison LL: Infant leukemia, topoisomerase II inhibitors, and the MLL gene. J Nat Cancer Inst 86:1678-1680, 1994
    • (1994) J Nat Cancer Inst , vol.86 , pp. 1678-1680
    • Ross, J.A.1    Potter, J.D.2    Robison, L.L.3
  • 53
    • 0028813641 scopus 로고
    • Intensification of treatment and survival in all children with lymphoblastic leukaemia: Results of UK Medical Research Council trial UKALL X
    • Chessells JM, Bailey C, Richards SM: Intensification of treatment and survival in all children with lymphoblastic leukaemia: Results of UK Medical Research Council trial UKALL X. Lancet 345:143-148, 1995
    • (1995) Lancet , vol.345 , pp. 143-148
    • Chessells, J.M.1    Bailey, C.2    Richards, S.M.3


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