Cytotoxic activities of phytochemicals from Ferula species

DARU, Journal of Pharmaceutical Sciences

Volumn 21, Issue 1, 2013, Pages

  Valiahdi, Seied Mojtaba ^a   Iranshahi, Mehrdad ^b   Sahebkar, Amirhossein ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cancer; Cytotoxicity; Ferula; Phytochemical

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 7 ISOPENTENYLOXYCOUMARIN; ACANTRIFOSIDE E; CONFERONE; DIVERSIN; FARNESIFEROL A; GALBANIC ACID; HERNIARIN; MOGOLTADONE; PLANT MEDICINAL PRODUCT; STYLOSIN; TSCHIMGINE; UMBELLIPRENIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG CYTOTOXICITY; FERULA; HUMAN; HUMAN CELL; IC 50; LUNG CANCER; MELANOMA; OVARY CARCINOMA;

EID: 84878600846     PISSN: 15608115     EISSN: 20082231     Source Type: Journal    
DOI: 10.1186/2008-2231-21-39     Document Type: Article

References (36)

1. Natural products as sources of new drugs over the period 1981-2002. Newman DJ, Cragg GM, Snader KM, J Nat Prod 2003 66 1022 1037 10.1021/np030096l 12880330
2. Cragg GM, Kingston DGI, Newman DJ, Anticancer Agents from Natural Products Boca Raton, FL: CRC Press 2005
3. Pimenov MG, Leonov MV, The genera of the Umbelliferae Kew, UK: Royal Botanic Gardens 1993
4. Sesquiterpenoids from the fruits of Ferula kuhistanica and antibacterial activity of the constituents of F. kuhistanica. Tamemoto K, Takais Y, Chen B, Kawazoe K, Shibata H, Higuti T, Honda G, Ito M, Takeda Y, Kodzhimatov OK, Ashurmetov O, Phytochemistry 2001 58 763 767 10.1016/S0031-9422(01)00307-7 11672742
5. Sesquiterpene Coumarins from Ferula fukanensis and Nitric Oxide Production Inhibitory Effects. Motai T, Daikonya A, Kitanaka S, J Nat Prod 2004 67 432 436 10.1021/np030408k 15043424
6. Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes. Iranshahi M, Arfa P, Ramezani M, Jaafari MR, Sadeghian H, Bassarello C, Piacente S, Pizza C, Phytochemistry 2007 68 554 561 10.1016/j.phytochem.2006.11.002 17196626
7. Sesquiterpene coumarins from the fruits of Ferula badrakema. Iranshahi M, Rezaee R, Sahebkar A, Bassarello C, Piacente S, Pizza C, Pharm Biol 2009 47 344 347 10.1080/13880200902752884
8. Synthesis and purification of 7- prenyloxycoumarins and herniarin as bioactive natural coumarins. Askari M, Sahebkar A, Iranshahi M, Iran J Basic Med Sci 2009 12 63 69
9. Purification and structure elucidation of compounds from the roots of Ferula ovina Boiss. Iranshahi M, Famili A, Bassarello C, Piacente S, Pizza C, Journal of Medicinal Plants 2010 9 72 80
10. A new coumarin from Ferula persica. Iranshahi M, Amin G, Shafiee A, Pharm Biol 2004 42 440 442 10.1080/13880200490886102
11. Diversolides A-G, guaianolides from the roots of Ferula diversivittata. Iranshahi M, Hosseini ST, Shahverdi AR, Molazade K, Khan SS, Ahmad VU, Phytochemistry 2008 69 2753 2757 10.1016/j.phytochem.2008.08.009 18804823
12. New sesquiterpene coumarins from the roots of Ferula flabelliloba. Iranshahi M, Kalategi F, Sahebkar A, Sardashti A, Schneider B, Pharm Biol 2010 48 217 220 10.3109/13880200903019226 20645844
13. Sesquiterpene coumarins from Ferula gumosa. Iranshahi M, Masullo M, Asili A, Hamedzadeh A, Jahanbin B, Festa M, Capasso A, Piacente S, J Nat Prod 2010 73 1958 1962 10.1021/np100487j 20961138
14. Polar secondary metabolites of Ferula persica roots. Iranshahi M, Mojarab M, Sadeghian H, Hanafi-Bojd MY, Schneider B, Phytochemistry 2008 69 473 478 10.1016/j.phytochem.2007.08.001 17854851
15. Conferone from Ferula schtschurowskiana enhances vinblastine cytotoxicity in MDCK-MDR1 cells by competitively inhibiting P-glycoprotein transport. Barthomeuf C, Demeule M, Grassi J, Saidkhodjaev A, Beliveau R, Planta Med 2006 72 634 639 10.1055/s-2006-931574 16739070
16. Cytotoxicity of vincristine on the 5637 cell line is enhanced by combination with conferone. Neshati V, Matin MM, Iranshahi M, Bahrami AR, Behravan J, Mollazadeh S, Rassouli FB, Z Naturforsch 2009 C 64 317 322
17. Investigating the cytotoxic and apoptosis inducing effects of monoterpenoid stylosin in vitro. Rassouli FB, Matin MM, Iranshahi M, Bahrami AR, Fitoterapia 2011 82 742 749 10.1016/j.fitote.2011.03.005 21459136
18. Rounaghi F, Moghaddam Matin M, Bahrami AR, Iranshahi M, Investigating the anti-cancer effects of tschimgine on MCF-7 cells in vitro 12th Iranian Pharmaceutical Sciences Congress. 2010 Available at: http://profdoc.um.ac.ir/ articles/a/1019668.pdf
19. Phytoestrogens and breast cancer. Baillieres. Barnes S, Clin Endocrinol Metab 1998 12 559 579
20. Phyto-oestrogens and cancer. Adlercreutz H, Lancet Oncol 2002 3 364 373 10.1016/S1470-2045(02)00777-5 12107024
21. Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented melanoma cells through cell-cycle arrest in G1 and induction of caspasedependent apoptosis. Barthomeuf C, Lim S, Iranshahi M, Chollet P, Phytomedicine 2008 15 103 111 10.1016/j.phymed.2007.04.001 17689942
22. Cancer chemopreventive activity of terpenoid coumarins from Ferula species. Iranshahi M, Kalategi F, Rezaee R, Shahverdi AR, Ito C, Furukawa H, Tokuda H, Itoigawa M, Planta Med 2008 74 147 150 10.1055/s-2008-1034293 18240102
23. Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo. Iranshahi M, Sahebkar A, Takasaki M, Konoshima T, Tokuda H, Eur J Cancer Prev 2009 18 412 415 10.1097/CEJ.0b013e32832c389e 19531956
24. Two matrix metalloproteinases inhibitors from Ferula persica var. persica. Shahverdi AR, Saadat F, Khorramizadeh MR, Iranshahi M, Khoshayand MR, Phytomedicine 2006 13 712 717 10.1016/j.phymed.2006.01.003 16487689
25. Galbanic acid isolated from Ferula assafoetida exerts in vivo anti-tumor activity in association with anti-angiogenesis and anti-proliferation. Kim KH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Kim HS, Zhang Y, Ryu SY, Lee MH, Lü J, Kim SH, Pharm Res 2011 28 597 609 10.1007/s11095-010-0311-7 21063754
26. Farnesiferol A from Ferula persica and Galbanic Acid from Ferula szowitsiana Inhibit P-Glycoprotein-Mediated Rhodamine Efflux in Breast Cancer Cell Lines. Hanafi-Bojd MY, Iranshahi M, Mosaffa F, Tehrani SO, Kalalinia F, Behravan J, Planta Med 2011 77 1590 1593 10.1055/s-0030-1270987 21484672
27. Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway. Hanif R, Qiao L, Schiff SJ, Rigas B, J Lab Clin Med 1997 130 576 584 10.1016/S0022-2143(97)90107-4 9422331
28. Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines. Mehta K, Pantazis P, McQueen T, Aggarwal BB, Anticancer Drugs 1997 8 470 481 10.1097/00001813-199706000-00010 9215611
29. The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in-vitro. Elattar TM, Virji AS, Anticancer Res 2000 20 1733 1738 10928101
30. Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway. Siwak DR, Shishodia S, Aggarwal BB, Kuzrock R, Cancer 2005 104 879 890 10.1002/cncr.21216 16007726
31. Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway. Lin YG, Kunnumakkara AB, Nair A, Merritt WM, Han LY, Armaiz-Pena GN, Kamat AA, Spannuth WA, Gershenson DM, Lutgendorf SK, Aggarwal BB, Sood AK, Clin Cancer Res 2007 13 3423 3430 10.1158/1078-0432.CCR-06-3072 17545551
32. Curcumin: An anti-inflammatory molecule from a curry spice on the path to cancer treatment. Basnet P, Skalko-Basnet N, Molecules 2011 16 4567 4598 10.3390/molecules16064567 21642934
33. Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma. Wilken R, Veena MS, Wang MB, Srivatsan ES, Mol Cancer 2011 10 12 10.1186/1476-4598-10-12 21299897
34. Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines. Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB, Oncogene 2001 20 7597 7609 10.1038/sj.onc.1204997 11753638
35. Who plays dual role in cancerous and normal cells? natural antioxidants or free radicals or the cell environment. Abdollahi M, Soodabeh S, Int J Pharmacol 2012 8 711 712 10.3923/ijp.2012.711.712
36. Antioxidant potential of various extracts from Ferula szovitsiana in relation to their phenolic content. Dehghan G, Shafiee A, Ghahremani MH, Ardestani SK, Abdollahi M, Pharm Biol 2007 45 691 699 10.1080/13880200701575098