A multicentre study to determine the value and safety of drug patch tests for the three main classes of severe cutaneous adverse drug reactions

British Journal of Dermatology

Volumn 168, Issue 3, 2013, Pages 555-562

  Barbaud, A ^a   Collet, E ^b   Milpied, B ^c   Assier, H ^d   Staumont, D ^e   Avenel Audran, M ^f   Grange, A ^g   Amarger, S ^h   Girardin, P ⁱ   Guinnepain, M T ^j,k   Truchetet, F ^l   Lasek, A ^m   Waton, J ^a  

^a UNIVERSITY HOSPITAL OF NANCY   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c BORDEAUX UNIVERSITY HOSPITAL   (France)

^d HENRI MONDOR HOSPITAL   (France)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f ANGERS UNIVERSITY HOSPITAL   (France)

^g REIMS UNIVERSITY HOSPITAL   (France)

^h UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

ⁱ HÔPITAL SAINT JACQUES   (France)

^j INSTITUT PASTEUR   (France)

^k FOCH HOSPITAL   (France)

^l Laboratory of Immunology   (France)

^m Dermatology Department   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS; ADOLESCENT; ADULT; AGED; ARTICLE; CHEMICALLY INDUCED DISORDER; DRUG ERUPTION; DRUG INTERACTION; EOSINOPHILIA; EVALUATION; FEMALE; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; PATCH TEST; STEVENS JOHNSON SYNDROME; TIME; TOXIC EPIDERMAL NECROLYSIS; VERY ELDERLY;

ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DRUG ERUPTIONS; DRUG INTERACTIONS; EOSINOPHILIA; EPIDERMAL NECROLYSIS, TOXIC; FEMALE; HUMANS; MALE; MIDDLE AGED; PATCH TESTS; STEVENS-JOHNSON SYNDROME; TIME FACTORS; YOUNG ADULT;

EID: 84878583525     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/bjd.12125     Document Type: Article

References (30)

1. Adam J, Pichler WJ, Yerly D. Delayed drug hypersensitivity: models of T-cell stimulation. Br J Clin Pharmacol 2011;71:701-7.
2. Barbaud A. Skin testing in delayed reactions to drugs. Immunol Allergy Clin North Am 2009;29:517-35.
3. Santiago F, Gonçalo M, Vieira R et al. Epicutaneous patch testing in drug hypersensitivity syndrome (DRESS). Contact Dermatitis 2010;62:47-53.
4. Gex-Collet C, Helbling A, Pichler WJ. Multiple drug hypersensitivity - proof of multiple drug hypersensitivity by patch and lymphocyte transformation tests. J Investig Allergol Clin Immunol 2005;15:293-6.
5. Picard D, Janela B, Descamps V et al. Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response. Sci Transl Med 2010;2:46ra62.
6. Kardaun SH, Sidoroff A, Valeyrie-Allanore L et al. Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist? Br J Dermatol 2006;155:422-8.
7. Barbaud A, Gonçalo M, Bruynzeel D, Bircher A. Guidelines for performing skin tests with drugs in the investigation of cutaneous adverse drug reactions. Contact Dermatitis 2001;45:321-8.
8. Brockow K, Romano A, Blanca M et al. General considerations for skin test procedures in the diagnosis of drug hypersensitivity. Allergy 2002;57:45-51.
9. Wolkenstein P, Chosidow O, Flechet M-L et al. Patch testing in severe cutaneous adverse drug reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis. Contact Dermatitis 1996;35:234-6.
10. Ueda T, Abe M, Okiyama R et al. Acute generalized exanthematous pustulosis due to allylisopropylacetylurea: role of IL-17-producing T cells. Eur J Dermatol 2011;21:140-1.
11. Britschgi M, Steiner UC, Schmid S et al. T-cell involvement in drug-induced acute generalized exanthematous pustulosis. J Clin Invest 2001;107:1433-41.
12. Thomas E, Bellón T, Barranco P et al. Acute generalized exanthematous pustulosis due to tetrazepam. J Investig Allergol Clin Immunol 2008;18:119-22.
13. Mashiah J, Brenner S. A systemic reaction to patch testing for the evaluation of acute generalized exanthematous pustulosis. Arch Dermatol 2003;139:1181-3.
14. Davidovici B, Dodiuk-Gad R, Rozenman D et al. Profile of acute generalized exanthematous pustulosis in Israel during 2002-2005: results of the RegiSCAR Study. Isr Med Assoc J 2008;10:410-12.
15. Sidoroff A, Dunant A, Viboud C et al. Risk factors for acute generalized exanthematous pustulosis (AGEP): results of a multinational case-control study (EuroSCAR). Br J Dermatol 2007;157:989-96.
16. Mardivirin L, Valeyrie-Allanore L, Branlant-Redon E et al. Amoxicillin-induced flare in patients with DRESS (drug reaction with eosinophilia and systemic symptoms): report of seven cases and demonstration of a direct effect of amoxicillin on human herpesvirus 6 replication in vitro. Eur J Dermatol 2010;20:68-73.
17. Lin YT, Chang YC, Hui RC et al. A patch testing and cross-sensitivity study of carbamazepine-induced severe cutaneous adverse drug reactions. J Eur Acad Dermatol Venereol 2012. doi: 10.1111/j.1468-3083.2011.04418.x
18. Shear N, Milpied B, Bruynzeel DP, Phillips E. A review of drug patch testing and implications for HIV clinicians. AIDS 2008;22:999-1007.
19. Lee JH, Park HK, Heo J et al. Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by celecoxib and anti-tuberculosis drugs. J Korean Med Sci 2008;23:521-5.
20. Kawakami T, Fujita A, Takeuchi S et al. Drug-induced hypersensitivity syndrome: drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome induced by aspirin treatment of Kawasaki disease. J Am Acad Dermatol 2009;60:146-9.
21. Aouam K, Bel Hadj Ali H, Youssef M et al. Carbamazepine-induced DRESS and HHV6 primary infection: the importance of skin tests. Epilepsia 2008;49:1630-3.
22. Suswardana, Hernanto M, Yudani BA et al. DRESS syndrome from cefadroxil confirmed by positive patch test. Allergy 2007;62:1216-17.
23. Daveluy A, Milpied B, Barbaud A et al. Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect? Eur J Clin Pharmacol 2012;68:101-5.
24. Ye YM, Kim JE, Kim JH et al. Propylthiouracil-induced DRESS syndrome confirmed by a positive patch test. Allergy 2010;65:407-9.
25. Caboni S, Gunera-Saad N, Ktiouet-Abassi S et al. Esomeprazoleinduced DRESS syndrome. Studies of cross-reactivity among proton-pump inhibitor drugs. Allergy 2007;62:1342-3.
26. Studer M, Waton J, Bursztejn A-C et al. La polysensibilisation médicamenteuse systémique existe-t-elle? Ann Dermatol Venereol 2012;139:375-80.
27. Pirmohamed M, Naisbitt DJ, Gordon F, Park BK. The danger hypothesis - potential role in idiosyncratic drug reactions. Toxicology 2002;2:55-63.
28. Gaig P, Garćia-Ortega P, Baltasar M, Bartra J. Drug neosensitization during anticonvulsant hypersensitivity syndrome. J Investig Allergol Clin Immunol 2006;16:321-6.
29. Chung WH, Hung SI, Yang JY et al. Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Nat Med 2008;14:1343-50.
30. Klein CE, Trautmann A, Zillikens D, Brocker EB. Patch testing in an unusual case of toxic epidermal necrolysis. Contact Dermatitis 1995;33:448-9.