Histone deacetylase inhibition by trichostatin A mitigates LPS induced TNFα and IL-10 production in human placental explants

Placenta

Volumn 34, Issue 7, 2013, Pages 567-573

  Munro, S K ^a   Mitchell, M D ^a,b   Ponnampalam, A P ^a,c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Cytokine; Epigenetic; HDAC; LPS; Placenta; TNF ; Trichostatin A

Indexed keywords

HISTONE DEACETYLASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; TRICHOSTATIN A; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; EPIGENETICS; FEMALE; HUMAN; HUMAN TISSUE; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ADULT; CYTOKINES; FEMALE; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; PLACENTA; PREGNANCY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878569733     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2013.04.004     Document Type: Article

References (37)

1. H. Wang, and S.K. Dey Roadmap to embryo implantation: clues from mouse models Nat Rev Genet 7 3 2006 Mar 185 199
2. S. Tranguch, T. Daikoku, Y. Guo, H. Wang, and S.K. Dey Molecular complexity in establishing uterine receptivity and implantation Cell Mol Life Sci 62 17 2005 Sep 1964 1973
3. T. Weissenbacher, R.P. Laubender, S.S. Witkin, A. Gingelmaier, B. Schiessl, and F. Kainer Influence of maternal age, gestational age and fetal gender on expression of immune mediators in amniotic fluid BMC Res Notes 5 2012 375
4. A. Sharma, A. Satyam, and J.B. Sharma Leptin, IL-10 and inflammatory markers (TNF-alpha, IL-6 and IL-8) in pre-eclamptic, normotensive pregnant and healthy non-pregnant women Am J Reprod Immunol 58 1 2007 Jul 21 30
5. E. Mullins, T. Prior, I. Roberts, and S. Kumar Changes in the maternal cytokine profile in pregnancies complicated by fetal growth restriction Am J Reprod Immunol 68 1 2012 Jul 1 7
6. C. Rusterholz, S. Hahn, and W. Holzgreve Role of placentally produced inflammatory and regulatory cytokines in pregnancy and the etiology of preeclampsia Semin Immunopathol 29 2 2007 Jun 151 162
7. J.A. Keelan, M. Blumenstein, R.J. Helliwell, T.A. Sato, K.W. Marvin, and M.D. Mitchell Cytokines, prostaglandins and parturition-a review Placenta 24 Suppl. A 2003 Apr S33 S46
8. M. Harper, S.L. Zheng, E. Thom, M.A. Klebanoff, J. Thorp Jr., and Y. Sorokin Cytokine gene polymorphisms and length of gestation Obstet Gynecol 117 1 2011 Jan 125 130
9. E. Moura, R. Mattar, E. de Souza, M.R. Torloni, A. Goncalves-Primo, and S. Daher Inflammatory cytokine gene polymorphisms and spontaneous preterm birth J Reprod Immunol 80 1-2 2009 Jun 115 121
10. G.A. Macones, S. Parry, M. Elkousy, B. Clothier, S.H. Ural, and J.F. Strauss 3rd A polymorphism in the promoter region of TNF and bacterial vaginosis: preliminary evidence of gene-environment interaction in the etiology of spontaneous preterm birth Am J Obstet Gynecol 190 6 2004 Jun 1504 1508 [discussion 3A]
11. H.J. Tsai, X. Liu, K. Mestan, Y. Yu, S. Zhang, and Y. Fang Maternal cigarette smoking, metabolic gene polymorphisms, and preterm delivery: new insights on GxE interactions and pathogenic pathways Hum Genet 123 4 2008 May 359 369
12. D.C. Dolinoy, J.R. Weidman, and R.L. Jirtle Epigenetic gene regulation: linking early developmental environment to adult disease Reprod Toxicol 23 3 2007 Apr-May 297 307
13. R.L. Jirtle, and M.K. Skinner Environmental epigenomics and disease susceptibility Nat Rev Genet 8 4 2007 Apr 253 262
14. X.J. Yang, and E. Seto HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention Oncogene 26 37 2007 Aug 13 5310 5318
15. F. Leoni, A. Zaliani, G. Bertolini, G. Porro, P. Pagani, and P. Pozzi The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines Proc Natl Acad Sci U S A 99 5 2002 Mar 5 2995 3000
16. K.A. Bode, K. Schroder, D.A. Hume, T. Ravasi, K. Heeg, and M.J. Sweet Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment Immunology 122 4 2007 Dec 596 606
17. T. Roger, J. Lugrin, D. Le Roy, G. Goy, M. Mombelli, and T. Koessler Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection Blood 117 4 2011 Jan 27 1205 1217
18. M.D. Mitchell, A.P. Ponnampalam, and G.E. Rice Epigenetic regulation of cytokine production in human amnion and villous placenta Mediators Inflamm 2012 159709
19. T.A. Sato, and M.D. Mitchell Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS Am J Physiol Endocrinol Metab 290 3 2006 Mar E490 E493
20. M.R. Peltier, E.M. Gurzenda, A. Murthy, K. Chawala, V. Lerner, and I. Kharode Can oxygen tension contribute to an abnormal placental cytokine milieu? Am J Reprod Immunol 66 4 2011 Oct 279 285
21. C. Royle, S. Lim, B. Xu, J. Tooher, R. Ogle, and A. Hennessy Effect of hypoxia and exogenous IL-10 on the pro-inflammatory cytokine TNF-alpha and the anti-angiogenic molecule soluble Flt-1 in placental villous explants Cytokine 47 1 2009 Jul 56 60
22. N.G. Reti, M. Lappas, B. Huppertz, C. Riley, M.E. Wlodek, and P. Henschke Effect of high oxygen on placental function in short-term explant cultures Cell Tissue Res 328 3 2007 Jun 607 616
23. M. Sullivan, P. Galea, and S. Latif What is the appropriate oxygen tension for in vitro culture? Mol Hum Reprod 12 11 2006 Nov 653
24. R.K. Miller, O. Genbacev, M.A. Turner, J.D. Aplin, I. Caniggia, and B. Huppertz Human placental explants in culture: approaches and assessments Placenta 26 6 2005 Jul 439 448
25. H. Bessler, M. Osovsky, B. Beilin, Y. Alcalay, and L. Sirota The existence of gender difference in IL-1Ra gene polymorphism J Interferon Cytokine Res 27 11 2007 Nov 931 935
26. M. Sadeghi, V. Daniel, C. Naujokat, R. Weimer, and G. Opelz Strikingly higher interleukin (IL)-1alpha, IL-1beta and soluble interleukin-1 receptor antagonist (sIL-1RA) but similar IL-2, sIL-2R, IL-3, IL-4, IL-6, sIL-6R, IL-10, tumour necrosis factor (TNF)-alpha, transforming growth factor (TGF)-beta and interferon IFN-gamma urine levels in healthy females compared to healthy males: protection against urinary tract injury? Clin Exp Immunol 142 2 2005 Nov 312 317
27. E. Elsmen, D. Ley, C.M. Cilio, I. Hansen-Pupp, and L. Hellstrom-Westas Umbilical cord levels of interleukin-1 receptor antagonist and neonatal outcome Biol Neonate 89 4 2006 220 226
28. K.E. Sullivan, A.B. Reddy, K. Dietzmann, A.R. Suriano, V.P. Kocieda, and M. Stewart Epigenetic regulation of tumor necrosis factor alpha Mol Cell Biol 27 14 2007 Jul 5147 5160
29. M.A. Halili, M.R. Andrews, M.J. Sweet, and D.P. Fairlie Histone deacetylase inhibitors in inflammatory disease Curr Top Med Chem 9 3 2009 309 319
30. J.M. Taylor, K. Wicks, C. Vandiedonck, and J.C. Knight Chromatin profiling across the human tumour necrosis factor gene locus reveals a complex, cell type-specific landscape with novel regulatory elements Nucleic Acids Res 36 15 2008 Sep 4845 4862
31. N. Hanna, I. Hanna, M. Hleb, E. Wagner, J. Dougherty, and D. Balkundi Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts J Immunol 164 11 2000 Jun 1 5721 5728
32. H. Zhu, L. Shan, P.W. Schiller, A. Mai, and T. Peng Histone deacetylase-3 activation promotes tumor necrosis factor-alpha (TNF-alpha) expression in cardiomyocytes during lipopolysaccharide stimulation J Biol Chem 285 13 2010 Mar 26 9429 9436
33. J. Gillespie, S. Savic, C. Wong, A. Hempshall, M. Inman, and P. Emery Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients Arthritis Rheum 64 2 2012 Feb 418 422
34. M.A. Halili, M.R. Andrews, L.I. Labzin, K. Schroder, G. Matthias, and C. Cao Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS J Leukoc Biol 87 6 2010 Jun 1103 1114
35. A. Schuetz, J. Min, A. Allali-Hassani, M. Schapira, M. Shuen, and P. Loppnau Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity J Biol Chem 283 17 2008 Apr 25 11355 11363
36. P. Bertrand Inside HDAC with HDAC inhibitors Eur J Med Chem 45 6 2010 Jun 2095 2116
37. S.L. Foster, and R. Medzhitov Gene-specific control of the TLR-induced inflammatory response Clin Immunol 130 1 2009 Jan 7 15