Early mineralocorticoid receptor blockade in primary percutaneous coronary intervention for ST-elevation myocardial infarction is associated with a reduction of life-threatening ventricular arrhythmia

International Journal of Cardiology

Volumn 167, Issue 1, 2013, Pages 73-79

  Beygui, Farzin ^a,b   Labbé, Jean Philippe ^a   Cayla, Guillaume ^c   Ennezat, Pierre Vladimir ^d   Motreff, Pascal ^e   Roubille, François ^f   Silvain, Johanne ^a,b   Barthélémy, Olivier ^a,b   Delarche, Nicolas ^g   Van Belle, Eric ^d   Collet, Jean Philippe ^a,b   Montalescot, Gilles ^a,b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b INSERM   (France)

^c Cardiology Department   (France)

^d Cardiology Hospital   (France)

^e Cardiology Department   (France)

^f MONTPELLIER UNIVERSITY HOSPITAL   (France)

^g Pau Hospital   (France)

Author keywords

Aldosterone; Angioplasty; Infarction; Sudden death; Ventricular arrhythmia

Indexed keywords

ALDOSTERONE; CANRENOATE POTASSIUM; MINERALOCORTICOID RECEPTOR; SPIRONOLACTONE;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; BOOTSTRAPPING; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY CARE UNIT; DEATH; FEMALE; FOLLOW UP; HEART ARREST; HEART FIBRILLATION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE TACHYCARDIA; HUMAN; MAJOR CLINICAL STUDY; MALE; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECEPTOR BLOCKING; RESUSCITATION; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; MINERALOCORTICOID RECEPTOR ANTAGONISTS; MYOCARDIAL INFARCTION; PERCUTANEOUS CORONARY INTERVENTION; PROSPECTIVE STUDIES; TACHYCARDIA, VENTRICULAR; TIME FACTORS; TREATMENT OUTCOME;

EID: 84878561373     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2011.11.076     Document Type: Article

References (43)

1. J.P. Benitah, E. Perrier, A.M. Gomez, and G. Vassort Effects of aldosterone on transient outward K + current density in rat ventricular myocytes J Physiol 537 Pt 1 2001 151 160
2. J.P. Benitah, and G. Vassort Aldosterone upregulates Ca(2 +) current in adult rat cardiomyocytes Circ Res 85 12 1999 1139 1145
3. R. Gomez, L. Nunez, R. Caballero, M. Vaquero, J. Tamargo, and E. Delpon Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1 + minK channels Br J Pharmacol 146 1 2005 146 161
4. A. Ouvrard-Pascaud, Y. Sainte-Marie, and J.P. Benitah Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias Circulation 111 23 2005 3025 3033
5. Y. Shimoni, K. Chen, T. Emmett, and G. Kargacin Aldosterone and the autocrine modulation of potassium currents and oxidative stress in the diabetic rat heart Br J Pharmacol 154 3 2008 675 687
6. A.T. Askari, M.H. Shishehbor, M.A. Kaminski, M.J. Riley, A. Hsu, and A.M. Lincoff The association between early ventricular arrhythmias, renin-angiotensin-aldosterone system antagonism, and mortality in patients with ST-segment-elevation myocardial infarction: insights from Global Use of Strategies to Open coronary arteries (GUSTO) V Am Heart J 158 2 2009 238 243
7. A.N. Cheema, K. Sheu, M. Parker, A.H. Kadish, and J.J. Goldberger Nonsustained ventricular tachycardia in the setting of acute myocardial infarction: tachycardia characteristics and their prognostic implications Circulation 98 19 1998 2030 2036
8. D.M. Henkel, B.J. Witt, and B.J. Gersh Ventricular arrhythmias after acute myocardial infarction: a 20-year community study Am Heart J 151 4 2006 806 812
9. A.P. Maggioni, G. Zuanetti, and M.G. Franzosi Prevalence and prognostic significance of ventricular arrhythmias after acute myocardial infarction in the fibrinolytic era. GISSI-2 results Circulation 87 2 1993 312 322
10. R.H. Mehta, A.Z. Starr, and R.D. Lopes Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention JAMA 301 17 2009 1779 1789
11. J.P. Piccini, J.S. Berger, and D.L. Brown Early sustained ventricular arrhythmias complicating acute myocardial infarction Am J Med 121 9 2008 797 804
12. S.G. Foy, I.G. Crozier, and A.M. Richards Neurohormonal changes after acute myocardial infarction. Relationships with haemodynamic indices and effects of ACE inhibition Eur Heart J 16 6 1995 770 778
13. A. Sigurdsson, P. Held, and K. Swedberg Short- and long-term neurohormonal activation following acute myocardial infarction Am Heart J 126 5 1993 1068 1076
14. F. Beygui, J.P. Collet, and J.J. Benoliel High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction Circulation 114 24 2006 2604 2610
15. B. Pitt, W. Remme, and F. Zannad Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction N Engl J Med 348 14 2003 1309 1321
16. B. Pitt, F. Zannad, and W.J. Remme The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators N Engl J Med 341 10 1999 709 717
17. F. Zannad, J.J. McMurray, and H. Krum Eplerenone in patients with systolic heart failure and mild symptoms N Engl J Med 364 1 2011 11 21
18. J. Fogliani, P. Capuccio, A. Goudard, J.C. Guillen, and J.R. Monties Value of soludactone in cardiac surgery in adults Ann Anesthesiol Fr 16 3 1975 189 196
19. K. Matsuda, N. Tatsuta, and Y. Konishi Therapeutic effect of canrenoate potassium (soldactone) in patients after open-heart surgery Nihon Geka Hokan 51 3 1982 519 527
20. R. Tufano, M. Scopa, G. Brando, and D. Leone Use of potassium canrenoate in cardiosurgery Minerva Anestesiol 47 4 1981 149 154
21. B. Denis, R. Dimitriou, J. Machecourt, J.E. Wolf, E. Page, and J.P. Reboud Hyperaldosteronism in the acute phase of myocardial infarction. Effects of its treatment on the prevention of ventricular fibrillation Arch Mal Coeur Vaiss 77 1984 35 40 Spec No
22. P. Di Pasquale, S. Cannizzaro, and S. Scalzo Effects of canrenoate plus angiotensin-converting enzyme inhibitors versus angiotensin-converting enzyme inhibitors alone on systolic and diastolic function in patients with acute anterior myocardial infarction Am Heart J 150 5 2005 919
23. I. Uzunhasan, A. Yildiz, and U. Coskun Effects of aldosterone blockade on left ventricular function and clinical status during acute myocardial infarction Scand J Clin Lab Invest 69 5 2009 545 549
24. M. Hayashi, T. Tsutamoto, and A. Wada Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction Circulation 107 20 2003 2559 2565
25. B. Pitt, H. White, and J. Nicolau Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure J Am Coll Cardiol 46 3 2005 425 431
26. F. Beygui, G. Montalescot, and E. Vicaut Aldosterone and long-term outcome after myocardial infarction: a substudy of the French nationwide Observatoire sur la Prise en charge hospitaliere, l'Evolution a un an et les caRacteristiques de patients presentant un infArctus du myocarde avec ou sans onde Q (OPERA) study Am Heart J 157 4 2009 680 687
27. B.R. Palmer, A.P. Pilbrow, and C.M. Frampton Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction Eur Heart J 29 20 2008 2489 2496
28. J.P. Piccini, M. Zhang, and K. Pieper Predictors of sudden cardiac death change with time after myocardial infarction: results from the VALIANT trial Eur Heart J 31 2 2010 211 221
29. K.A. Eagle, M.J. Lim, and O.H. Dabbous A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry JAMA 291 22 2004 2727 2733
30. R. Perrier, S. Richard, and Y. Sainte-Marie A direct relationship between plasma aldosterone and cardiac L-type Ca2 + current in mice J Physiol 569 Pt 1 2005 153 162
31. J. Wei, J. Ni, D. Huang, M. Chen, S. Yan, and Y. Peng The effect of aldosterone antagonists for ventricular arrhythmia: a meta-analysis Clin Cardiol 33 9 2010 572 577
32. H.V. Huikuri, A. Castellanos, and R.J. Myerburg Sudden death due to cardiac arrhythmias N Engl J Med 345 20 2001 1473 1482
33. D. Mehta, J. Curwin, J.A. Gomes, and V. Fuster Sudden death in coronary artery disease: acute ischemia versus myocardial substrate Circulation 96 9 1997 3215 3223
34. B.K. Yeh, B.N. Chiang, and P.K. Sung Antiarrhythmic activity of potassium canrenoate in man Am Heart J 92 3 1976 308 314
35. S.D. Solomon, S. Zelenkofske, and J.J. McMurray Sudden death in patients with myocardial infarction and left ventricular dysfunction, heart failure, or both N Engl J Med 352 25 2005 2581 2588
36. D.S. Echt, P.R. Liebson, and L.B. Mitchell Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial N Engl J Med 324 12 1991 781 788
37. A.L. Waldo, A.J. Camm, and H. deRuyter Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction. The SWORD Investigators. Survival With Oral d-Sotalol Lancet 348 9019 1996 7 12
38. J.L. Rouleau, M. Packer, and L. Moye Prognostic value of neurohumoral activation in patients with an acute myocardial infarction: effect of captopril J Am Coll Cardiol 24 3 1994 583 591
39. F. Beygui, J. Silvain, and A. Pena Usefulness of a biomarker strategy to improve GRACE score's prediction performance in patients with non-ST-elevation acute coronary syndrome and low event rates Am J Cardiol 106 2010 650 658
40. G. Montalescot, H. Drexler, R. Gallo, T. Pearson, M. Thoenes, and D.L. Bhatt Effect of irbesartan and enalapril in non-ST elevation acute coronary syndrome: results of the randomized, double-blind ARCHIPELAGO study Eur Heart J 30 22 2009 2733 2741
41. E. Perrier, B.G. Kerfant, and N. Lalevee Mineralocorticoid receptor antagonism prevents the electrical remodeling that precedes cellular hypertrophy after myocardial infarction Circulation 110 7 2004 776 783
42. A.D. Struthers Aldosterone: cardiovascular assault Am Heart J 144 5 Suppl 2002 S2 S7
43. F. Beygui, E. Vicaut, and P. Ecollan Rationale for an early aldosterone blockade in acute myocardial infarction and design of the ALBATROSS trial Am Heart J 160 4 2010 642 648