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Volumn 113, Issue 3, 2013, Pages 763-773

Alterations in purine metabolism in middle-aged elite, amateur, and recreational runners across a 1-year training cycle

Author keywords

HGPRT; Hypoxanthine; Master athletes; Training cycle

Indexed keywords


EID: 84878553523     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-012-2488-4     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 0037503077 scopus 로고    scopus 로고
    • Glycogen availability does not affect the TCA cycle or TAN pools during prolonged, fatiguing exercise
    • 12736189 1:CAS:528:DC%2BD3sXkvVyjtbg%3D
    • Baldwin J, Snow RJ, Gibala MJ, Garnham A, Howarth K, Febbraio MA (2003) Glycogen availability does not affect the TCA cycle or TAN pools during prolonged, fatiguing exercise. J Appl Physiol 94:2181-2187
    • (2003) J Appl Physiol , vol.94 , pp. 2181-2187
    • Baldwin, J.1    Snow, R.J.2    Gibala, M.J.3    Garnham, A.4    Howarth, K.5    Febbraio, M.A.6
  • 3
    • 0022542458 scopus 로고
    • A new method for detecting anaerobic threshold by gas exchange
    • 3087938 1:STN:280:DyaL283ltVCrug%3D%3D
    • Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60:2020-2027
    • (1986) J Appl Physiol , vol.60 , pp. 2020-2027
    • Beaver, W.L.1    Wasserman, K.2    Whipp, B.J.3
  • 4
    • 0021014688 scopus 로고
    • Pattern of venous lactate and pyruvate after submaximal exercise in athletes training in different disciplines
    • 6654551 10.1055/s-2008-1026044 1:CAS:528:DyaL2cXhtFymtr8%3D
    • Bhattacharya AK, Panda PK, Das Gupta PK, De AK (1983) Pattern of venous lactate and pyruvate after submaximal exercise in athletes training in different disciplines. Int J Sports Med 4:252-254
    • (1983) Int J Sports Med , vol.4 , pp. 252-254
    • Bhattacharya, A.K.1    Panda, P.K.2    Das Gupta, P.K.3    De, A.K.4
  • 8
    • 0000831018 scopus 로고
    • L-/± lactate determination with lactate dehydrogenase and NAD
    • H.U. Bergmayer (eds) Academic Press New York
    • Gutmann J, Wahlenfeld AW (1974) l-/± lactate determination with lactate dehydrogenase and NAD. In: Bergmayer HU (ed) Methods of enzymatic analysis. Academic Press, New York, pp 1586-1587
    • (1974) Methods of Enzymatic Analysis , pp. 1586-1587
    • Gutmann, J.1    Wahlenfeld, A.W.2
  • 9
    • 0020657143 scopus 로고
    • Purine transport and metabolism in man: The effect of exercise on concentrations of purine bases, nucleosides and nucleotides in plasma urine, leucocytes and erythrocytes
    • 1:CAS:528:DyaL3sXhsVWhsLw%3D
    • Harkness RA, Simmonds RJ, Coade SB (1983) Purine transport and metabolism in man: the effect of exercise on concentrations of purine bases, nucleosides and nucleotides in plasma urine, leucocytes and erythrocytes. Clin Sci (Lond) 64:333-340
    • (1983) Clin Sci (Lond) , vol.64 , pp. 333-340
    • Harkness, R.A.1    Simmonds, R.J.2    Coade, S.B.3
  • 10
    • 0024434624 scopus 로고
    • The metabolic relation between hypoxanthine and uric acid in man following maximal short-distance running
    • 10.1111/j.1748-1716.1989.tb08762.x
    • Hellsten-Westing Y, Ekblom B, Sjödin B (1989) The metabolic relation between hypoxanthine and uric acid in man following maximal short-distance running. Acta Physiol Scand 137:341-345
    • (1989) Acta Physiol Scand , vol.137 , pp. 341-345
    • Hellsten-Westing, Y.1    Ekblom, B.2    Sjödin, B.3
  • 11
    • 0025908522 scopus 로고
    • Plasma accumulation of hypoxanthine, uric acid and creatine kinase following exhausting runs of differing durations in man
    • 1874247 10.1007/BF00634977 1:STN:280:DyaK3MzjvFymtA%3D%3D
    • Hellsten-Westing Y, Sollevi A, Sjödin B (1991) Plasma accumulation of hypoxanthine, uric acid and creatine kinase following exhausting runs of differing durations in man. Eur J Appl Physiol Occup Physiol 62:380-384
    • (1991) Eur J Appl Physiol Occup Physiol , vol.62 , pp. 380-384
    • Hellsten-Westing, Y.1    Sollevi, A.2    Sjödin, B.3
  • 12
    • 0027716865 scopus 로고
    • The effect of high-intensity training on purine metabolism in man
    • 8128888 10.1111/j.1748-1716.1993.tb09636.x 1:CAS:528:DyaK2cXhtVeisLs%3D
    • Hellsten-Westing Y, Balsom PD, Norman B, Sjödin B (1993a) The effect of high-intensity training on purine metabolism in man. Acta Physiol Scand 149:405-412
    • (1993) Acta Physiol Scand , vol.149 , pp. 405-412
    • Hellsten-Westing, Y.1    Balsom, P.D.2    Norman, B.3    Sjödin, B.4
  • 13
    • 0027309559 scopus 로고
    • Decreased resting levels of adenine nucleotides in human skeletal muscle after high-intensity training
    • 8335586 1:CAS:528:DyaK3sXmtVSms7g%3D
    • Hellsten-Westing Y, Norman B, Balsom PD, Sjödin B (1993b) Decreased resting levels of adenine nucleotides in human skeletal muscle after high-intensity training. J Appl Physiol 74:2523-2528
    • (1993) J Appl Physiol , vol.74 , pp. 2523-2528
    • Hellsten-Westing, Y.1    Norman, B.2    Balsom, P.D.3    Sjödin, B.4
  • 14
    • 0028089339 scopus 로고
    • Exchange of purines in human liver and skeletal muscle with short-term exhaustive exercise
    • 8304559 1:CAS:528:DyaK2cXhsF2qurc%3D
    • Hellsten-Westing Y, Kaijser L, Ekblom B, Sjödin B (1994) Exchange of purines in human liver and skeletal muscle with short-term exhaustive exercise. Am J Physiol 266:R81-R86
    • (1994) Am J Physiol , vol.266
    • Hellsten-Westing, Y.1    Kaijser, L.2    Ekblom, B.3    Sjödin, B.4
  • 15
    • 0029970717 scopus 로고    scopus 로고
    • Oxidation of urate in human skeletal muscle during exercise
    • 8958141 10.1016/S0891-5849(96)00286-9 1:CAS:528:DyaK28XnsVGjur8%3D
    • Hellsten Y, Tullson PC, Richter EA, Bangsbo J (1997) Oxidation of urate in human skeletal muscle during exercise. Free Radic Biol Med 22:169-174
    • (1997) Free Radic Biol Med , vol.22 , pp. 169-174
    • Hellsten, Y.1    Tullson, P.C.2    Richter, E.A.3    Bangsbo, J.4
  • 16
    • 0033230853 scopus 로고    scopus 로고
    • AMP deamination and purine exchange in human skeletal muscle during and after intense exercise
    • 10545153 10.1111/j.1469-7793.1999.00909.x 1:CAS:528:DyaK1MXns1elsrg%3D
    • Hellsten Y, Richter EA, Kiens B, Bangsbo J (1999) AMP deamination and purine exchange in human skeletal muscle during and after intense exercise. J Physiol 520:909-920
    • (1999) J Physiol , vol.520 , pp. 909-920
    • Hellsten, Y.1    Richter, E.A.2    Kiens, B.3    Bangsbo, J.4
  • 17
    • 0035584273 scopus 로고    scopus 로고
    • Allantoin formation and urate and glutathione exchange in human muscle during submaximal exercise
    • 11728802 10.1016/S0891-5849(01)00631-1 1:CAS:528:DC%2BD3MXos1Knu7o%3D
    • Hellsten Y, Svensson M, Sjödin B, Smith S, Christensen A, Richter EA, Bangsbo J (2001) Allantoin formation and urate and glutathione exchange in human muscle during submaximal exercise. Free Radic Biol Med 31:1313-1322
    • (2001) Free Radic Biol Med , vol.31 , pp. 1313-1322
    • Hellsten, Y.1    Svensson, M.2    Sjödin, B.3    Smith, S.4    Christensen, A.5    Richter, E.A.6    Bangsbo, J.7
  • 18
    • 28444460265 scopus 로고    scopus 로고
    • Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise
    • 16324927 10.1016/j.metabol.2005.07.013 1:CAS:528:DC%2BD2MXht1Oms7fN
    • Kaya M, Moriwaki Y, Ka T, Inokuchi T, Yamamoto A, Takahashi S, Tsutsumi Z, Tsuzita J, Oku Y, Yamamoto T (2006) Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise. Metabolism 55:103-107
    • (2006) Metabolism , vol.55 , pp. 103-107
    • Kaya, M.1    Moriwaki, Y.2    Ka, T.3    Inokuchi, T.4    Yamamoto, A.5    Takahashi, S.6    Tsutsumi, Z.7    Tsuzita, J.8    Oku, Y.9    Yamamoto, T.10
  • 19
    • 0015317149 scopus 로고
    • Ammonia production in muscle and other tissues: The purine nucleotide cycle
    • Löwenstein JM (1972) Ammonia production in muscle and other tissues: the purine nucleotide cycle. Physiol Rev 52:382-414
    • (1972) Physiol Rev , vol.52 , pp. 382-414
    • Löwenstein, J.M.1
  • 20
    • 0021175649 scopus 로고
    • Control of the purine nucleotide cycle in extracts of rat skeletal muscle: Effects of energy state and concentrations of cycle intermediates
    • 6486798 10.1016/0003-9861(84)90475-2 1:CAS:528:DyaL2cXlt1Gku7s%3D
    • Manfredi JP, Holmes EW (1984) Control of the purine nucleotide cycle in extracts of rat skeletal muscle: effects of energy state and concentrations of cycle intermediates. Arch Biochem Biophys 233:515-529
    • (1984) Arch Biochem Biophys , vol.233 , pp. 515-529
    • Manfredi, J.P.1    Holmes, E.W.2
  • 21
    • 0015747270 scopus 로고
    • Myocardial nucleotide synthesis from purine bases and nucleosides. Comparison of the rates of formation of purine nucleotides from various precursors and identification of the enzymatic routes for nucleotide formation in the isolated rat heart
    • 4357569 10.1161/01.RES.33.6.686 1:CAS:528:DyaE2cXks1SksA%3D%3D
    • Namm DH (1973) Myocardial nucleotide synthesis from purine bases and nucleosides. Comparison of the rates of formation of purine nucleotides from various precursors and identification of the enzymatic routes for nucleotide formation in the isolated rat heart. Circ Res 33:686-695
    • (1973) Circ Res , vol.33 , pp. 686-695
    • Namm, D.H.1
  • 24
    • 0025330404 scopus 로고
    • Adenine nucleotide depletion in human muscle during exercise: Causality and significance of AMP deamination
    • 2361781 10.1055/s-2007-1024856
    • Sahlin K, Broberg S (1990) Adenine nucleotide depletion in human muscle during exercise: causality and significance of AMP deamination. Int J Sports Med 11:S62-S67
    • (1990) Int J Sports Med , vol.11
    • Sahlin, K.1    Broberg, S.2
  • 25
    • 0025877196 scopus 로고
    • Changes in plasma hypoxanthine and free radical markers during exercise in man
    • 1877376 10.1111/j.1748-1716.1991.tb09157.x 1:CAS:528:DyaK3MXks12htLo%3D
    • Sahlin K, Ekberg K, Cizinsky S (1991) Changes in plasma hypoxanthine and free radical markers during exercise in man. Acta Physiol Scand 142:275-281
    • (1991) Acta Physiol Scand , vol.142 , pp. 275-281
    • Sahlin, K.1    Ekberg, K.2    Cizinsky, S.3
  • 26
    • 0032822050 scopus 로고    scopus 로고
    • Plasma hypoxanthine and ammonia in humans during prolonged exercise
    • 10502075 10.1007/s004210050613 1:CAS:528:DyaK1MXls1CqtL8%3D
    • Sahlin K, Tonkonogi M, Söderlund K (1999) Plasma hypoxanthine and ammonia in humans during prolonged exercise. Eur J Appl Physiol Occup Physiol 80:417-422
    • (1999) Eur J Appl Physiol Occup Physiol , vol.80 , pp. 417-422
    • Sahlin, K.1    Tonkonogi, M.2    Söderlund, K.3
  • 27
    • 0033125484 scopus 로고    scopus 로고
    • Relation between changes in serum hypoxanthine levels by exercise and daily physical activity in the elderly
    • 10494902 10.1620/tjem.188.71 1:CAS:528:DyaK1MXkvVGnu7s%3D
    • Saiki S, Sato T, Hiwatari M, Harada T, Oouchi M, Kamimoto M (1999) Relation between changes in serum hypoxanthine levels by exercise and daily physical activity in the elderly. Tohoku J Exp Med 188:71-74
    • (1999) Tohoku J Exp Med , vol.188 , pp. 71-74
    • Saiki, S.1    Sato, T.2    Hiwatari, M.3    Harada, T.4    Oouchi, M.5    Kamimoto, M.6
  • 28
    • 0025201162 scopus 로고
    • Changes in plasma concentration of hypoxanthine and uric acid in man with short-distance running at various intensities
    • 2286490 10.1055/s-2007-1024844
    • Sjödin B, Hellsten-Westing Y (1990) Changes in plasma concentration of hypoxanthine and uric acid in man with short-distance running at various intensities. Int J Sports Med 11:493-495
    • (1990) Int J Sports Med , vol.11 , pp. 493-495
    • Sjödin, B.1    Hellsten-Westing, Y.2
  • 30
    • 16644383630 scopus 로고    scopus 로고
    • Longitudinal assessment of the effects of field hockey training on repeated sprint ability
    • 15518297 10.1016/S1440-2440(04)80027-6 1:STN:280:DC%2BD2crks1Kmug%3D%3D
    • Spencer M, Bishop D, Lawrence S (2004) Longitudinal assessment of the effects of field hockey training on repeated sprint ability. J Sci Med Sport 7:323-334
    • (2004) J Sci Med Sport , vol.7 , pp. 323-334
    • Spencer, M.1    Bishop, D.2    Lawrence, S.3
  • 31
    • 0030445908 scopus 로고    scopus 로고
    • ATP: The red blood cell link to NO and local control of the pulmonary circulation
    • 8997335 1:CAS:528:DyaK2sXmt1ejug%3D%3D
    • Sprague RS, Ellsworth ML, Stephenson AH, Lonigro AJ (1996) ATP: the red blood cell link to NO and local control of the pulmonary circulation. Am J Physiol 271:H2717-H2722
    • (1996) Am J Physiol , vol.271
    • Sprague, R.S.1    Ellsworth, M.L.2    Stephenson, A.H.3    Lonigro, A.J.4
  • 32
    • 0028210633 scopus 로고
    • Influence of sprint training on human skeletal muscle purine nucleotide metabolism
    • 8045862 1:CAS:528:DyaK2cXltVGitb0%3D
    • Stathis CG, Febbraio MA, Carey MF, Snow RJ (1994) Influence of sprint training on human skeletal muscle purine nucleotide metabolism. J Appl Physiol 76:1802-1809
    • (1994) J Appl Physiol , vol.76 , pp. 1802-1809
    • Stathis, C.G.1    Febbraio, M.A.2    Carey, M.F.3    Snow, R.J.4
  • 33
    • 34047112916 scopus 로고    scopus 로고
    • Sprint training reduces urinary purine loss following intense exercise in humans
    • 17213884 10.1139/h06-074
    • Stathis CG, Carey MF, Hayes A, Garnham AP, Snow RJ (2006) Sprint training reduces urinary purine loss following intense exercise in humans. Appl Physiol Nutr Metab 31:702-708
    • (2006) Appl Physiol Nutr Metab , vol.31 , pp. 702-708
    • Stathis, C.G.1    Carey, M.F.2    Hayes, A.3    Garnham, A.P.4    Snow, R.J.5
  • 34
    • 0028950941 scopus 로고
    • Purine enzyme activities in peripheral blood mononuclear cells: Comparison of a new non-radiochemical high-performance liquid chromatography procedure and a radiochemical thin-layer chromatography procedure
    • 10.1016/0378-4347(94)00571-L 1:CAS:528:DyaK2MXkvFKjsLg%3D
    • Stolk JN, De Abreu RA, Boerbooms AM, de Koning DG, de Graaf R, Kerstens PJ, van de Putte LB (1995) Purine enzyme activities in peripheral blood mononuclear cells: comparison of a new non-radiochemical high-performance liquid chromatography procedure and a radiochemical thin-layer chromatography procedure. J Chromatogr B 666:33-43
    • (1995) J Chromatogr B , vol.666 , pp. 33-43
    • Stolk, J.N.1    De Abreu, R.A.2    Boerbooms, A.M.3    De Koning, D.G.4    De Graaf, R.5    Kerstens, P.J.6    Van De Putte, L.B.7
  • 35
    • 0018834083 scopus 로고
    • Purine metabolism during strenuous muscular exercise in man
    • 7374440 10.1016/0026-0495(80)90067-0 1:CAS:528:DyaL3cXptF2muw%3D%3D
    • Sutton JR, Toews CJ, Ward GR, Fox IH (1980) Purine metabolism during strenuous muscular exercise in man. Metabolism 29:254-260
    • (1980) Metabolism , vol.29 , pp. 254-260
    • Sutton, J.R.1    Toews, C.J.2    Ward, G.R.3    Fox, I.H.4
  • 36
    • 0025997043 scopus 로고
    • Adenine nucleotide synthesis in exercising and endurance-trained skeletal muscle
    • 1908187 1:CAS:528:DyaK3MXlsFGqt7o%3D
    • Tullson PC, Terjung RL (1991) Adenine nucleotide synthesis in exercising and endurance-trained skeletal muscle. Am J Physiol 261:C342-C347
    • (1991) Am J Physiol , vol.261
    • Tullson, P.C.1    Terjung, R.L.2
  • 37
    • 0019132291 scopus 로고
    • Simultaneous liquid chromatography of 5-fluorouracil, uridine, hypoxanthine, xanthine, uric acid, allopurinol and oxipurinol in plasma
    • 7428153 1:CAS:528:DyaL3MXktlCqsA%3D%3D
    • Wung WE, Howell SB (1980) Simultaneous liquid chromatography of 5-fluorouracil, uridine, hypoxanthine, xanthine, uric acid, allopurinol and oxipurinol in plasma. Clin Chem 26:1704-1708
    • (1980) Clin Chem , vol.26 , pp. 1704-1708
    • Wung, W.E.1    Howell, S.B.2
  • 38
    • 84859575998 scopus 로고    scopus 로고
    • Training-inducted adaptation in purine metabolism in high-level sprinters vs. triathletes
    • 22162524 10.1152/japplphysiol.01292.2011
    • Zieliński J, Kusy K (2012) Training-inducted adaptation in purine metabolism in high-level sprinters vs. triathletes. J Appl Physiol 112:542-551
    • (2012) J Appl Physiol , vol.112 , pp. 542-551
    • Zieliński, J.1    Kusy, K.2
  • 39
    • 68349131760 scopus 로고    scopus 로고
    • The effect of endurance training on changes in purine metabolism: A longitudinal study of competitive long-distance runners
    • 19479277 10.1007/s00421-009-1079-5
    • Zieliński J, Rychlewski T, Kusy K, Domaszewska K, Laurentowska M (2009) The effect of endurance training on changes in purine metabolism: a longitudinal study of competitive long-distance runners. Eur J Appl Physiol 106:867-876
    • (2009) Eur J Appl Physiol , vol.106 , pp. 867-876
    • Zieliński, J.1    Rychlewski, T.2    Kusy, K.3    Domaszewska, K.4    Laurentowska, M.5
  • 40
    • 85027935719 scopus 로고    scopus 로고
    • Effect of training load structure on purine metabolism in middle-distance runners
    • 21364483 10.1249/MSS.0b013e318215d10b
    • Zieliński J, Kusy K, Rychlewski T (2011) Effect of training load structure on purine metabolism in middle-distance runners. Med Sci Sports Exerc 43:1798-1807
    • (2011) Med Sci Sports Exerc , vol.43 , pp. 1798-1807
    • Zieliński, J.1    Kusy, K.2    Rychlewski, T.3


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