Sprint training reduces urinary purine loss following intense exercise in humans

Applied Physiology, Nutrition and Metabolism

Volumn 31, Issue 6, 2006, Pages 702-708

  Stathis, Christos G ^a   Carey, Michael F ^a   Hayes, Alan ^a   Garnham, Andrew P ^b   Snow, Rodney J ^b  

^a VICTORIA UNIVERSITY   (Australia)

^b DEAKIN UNIVERSITY   (Australia)

Author keywords

Hypoxanthine; Inosine; Metabolism; Sprint training; Uric acid

Indexed keywords

HYPOXANTHINE; INOSINE; PURINE DERIVATIVE; URIC ACID;

ADULT; ARTICLE; BLOOD; HUMAN; MALE; METABOLISM; MUSCLE; OSMOLARITY; PHYSICAL EDUCATION; RUNNING; TIME; URINE;

ADULT; HUMANS; HYPOXANTHINE; INOSINE; MALE; MUSCLES; OSMOLAR CONCENTRATION; PHYSICAL EDUCATION AND TRAINING; PURINES; RUNNING; TIME FACTORS; URIC ACID;

EID: 34047112916     PISSN: 17155312     EISSN: None     Source Type: Journal    
DOI: 10.1139/H06-074     Document Type: Article

References (27)

1. Balsom, P.D., Seger, J.Y., Sjodin, B., and Ekblom, B. 1992a. Physiological responses to maximal intensity intermittent exercise, Eur. J. Appl. Physiol. Occup. Physiol. 65: 144-149. PMID:1396638.
2. Balsom, P.D., Seger, J.Y., Sjodin, B., and Ekblom, B. 1992a. Maximal-intensity intermittent exercise: effect of recovery duration. Int. J. Sports Med. 13: 528-533. PMID: 1459748.
3. Bangsbo, J., Sjodin, B., and Hellsten-Westing, Y. 1992. Exchange of hypoxanthine in muscle during intense exercise in man. Acta Physiol. Scand. 146: 549-550. PMID: 1492576.
4. Burgomaster, K.A., Hughes, S.C., Heigenhauser, G.J., Bradwell, S.N., and Gibala, M.J. 2005. Six sessions of sprint interval training increases muscle oxidative potential and cycle endurance capacity in humans. J. Appl. Physiol. 98: 1985-1990. doi:10.1152/japplphysiol.01095.2004. PMID: 15705728.
5. Harmer, A.R., McKenna, M.J., Sutton, J.R., Snow, R.J., Ruell, P.A., and Booth, J. 2000. Skeletal muscle metabolic and ionic adaptations during intense exercise following sprint training in humans. J. Appl. Physiol. 89: 1793-1803. PMID: 11053328.
6. Harris, R.C., Hultman, E., and Nordesjo, L.-O. 1974. Glycogen, glycolytic intermediates and high energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values. Scand. J. Clin. Lab. Invest. 33: 109-120. PMID:4852173.
7. Hellsten, Y., Richter, E.A., Kiens, B., and Bangsbo, J. 1999. AMP deamination and purine exchange in human skeletal muscle during and after intense exercise. J. Physiol. 520: 909-920. doi:10.1111/j.1469-7793.1999. 00909.x. PMID: 10545153.
8. Hellsten, Y., Skadhauge, L., and Bangsbo, J. 2004. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286: R182-R188. PMID: 14660478.
9. Hellsten-Westing, Y., Norman, B., Balsom, P.D., and Sjodin, B. 1993a. Decreased resting levels of adenine nucleotides in human skeletal muscle after high-intensity training. J, Appl. Physiol. 74: 2523-2528. PMID:8335586.
10. Hellsten-Westing, Y., Balsom, P.D., Norman, B., and Sjodin, B, 1993a. The effect of high-intensity training on purine metabolism in man. Acta Physiol. Scand. 149: 405-412. PMID:8128888.
11. Hellsten-Westing, Y., Kaijser, L., Ekblom, B., and Sjodin, B. 1994. Exchange of purines in human liver and skeletal muscle with short-term exhaustive exercise. Am. J. Physiol. Regul. Integr. Comp. Physiol. 266: R81-R86. PMID:8304559.
12. Lowenstein, J.M. 1990. The purine nucleotide cycle revisited. Int. J. Sports Med. 11: Suppl 2, S37-S46. PMID:2193892.
13. Lowry, O., and Passoneau, J. 1972. A flexible system of enzymatic analysis. Academic Press, New York, N.Y.
14. Meyer, R.A., and Terjung, R.L. 1980. AMP deamination and IMP reamination in working skeletal muscle. Am. J. Physiol. 239: C32-C38. PMID:7395984.
15. Nasrallah, S., and Al-Khalidi, U. 1964. Nature of purines excreted in urine during muscular exercise. J. Appl. Physiol. 19: 246-248. PMID: 14155289.
16. Parra, J., Cadefau, J.A., Rodas, G., Amigo, N., and Cusso, R. 2000. The distribution of rest periods affects performance and adaptations of energy metabolism induced by high-intensity training in human muscle. Acta Physiol. Scand. 169: 157-165. doi:10.1046/j. 1365-201x.2000.00730.x. PMID: 10848646.
17. Raggi, A., and Ranieri-Raggi, M. 1987. Regulatory properties of AMP deaminase isoenzymes from rabbit red muscle. Biochem. J. 242: 875-879. PMID:3593281.
18. Rush, J.W., Tullson, P.C., and Terjung, R.L. 1998. Molecular and kinetic alterations of muscle AMP deaminase during chronic creatine depletion. Am. J. Physiol. 274: C465-C471. PMID:9486137.
19. Sjodin, B., and Hellsten-Westing, Y. 1990. Changes in plasma concentration of hypoxanthine and uric acid in man with short distance running at various intensities. Int. J. Sports Med. 11: 493-495. PMID:2286490.
20. Snyder, W., Cook, E., Nasset, L., Karhausen, L., Howells, G., and Tipton, I. 1975. Report of the task group on reference man. Permagon Press, Oxford, UK.
21. Sorensen, L.B., and Levinson, D.J. 1975. Origin and extrarenal elimination of uric acid in man. Nephron, 14: 7-20. PMID: 1124137.
22. Stathis, C.G., Febbraio, M.A., Carey, M.F., and Snow, R.J. 1994. Influence of sprint training on human skeletal muscle purine nucleotide metabolism. J. Appl. Physiol. 76: 1802-1809. PMID:8045862.
23. Stathis, C.G., Zhao, S., Carey, M.F., and Snow, R.J. 1999. Purine loss after repeated sprint bouts in humans. J. Appl. Physiol. 87: 2037-2042. PMID: 10601147.
24. Sutton, J.R., Toews, C.J., Ward, G.R., and Fox, I.H. 1980. Purine metabolism during strenuous muscular exercise in man. Metabolism, 29: 254-260. doi: 10.1016/0026-0495(80)90067-0. PMID:7374440.
25. Tullson, P.C., Bangsbo, J., Hellsten, Y., and Richter, E.A. 1995. IMP metabolism in human skeletal muscle after exhaustive exercise. J. Appl. Physiol. 78: 146-152. PMID:7713804.
26. Wheeler, T.J., and Lowenstein, J.M. 1979. Adenylate deaminase from rat muscle. Regulation by purine nucleotides and orthophosphate in the presence of 150 mmol/L KCl. J. Biol. Chem. 254: 8994-8999. PMID:479176.
27. Wynants, J., and Van Belle, H. 1985. Single-run high-performanceliquid chromatography of nucleotides, nucleosides, and major purine bases and its application to different tissue extracts. Anal. Biochem. 144: 258-266. doi: 10.1016/0003-2697(85) 90114-9. PMID:3985319.