Leukocyte enrichment based on a modified pinched flow fractionation approach

Microfluidics and Nanofluidics

Volumn 14, Issue 3-4, 2013, Pages 551-563

  Cupelli, Claudio ^a   Borchardt, Thorsten ^a   Steiner, Thomas ^a   Paust, Nils ^c   Zengerle, Roland ^a,c   Santer, Mark ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^c Institut für Mikro und Informationstechnik   (Germany)

Author keywords

Cell sorting; Dissipative particle dynamics; Micro total analysis systems; Microfluidics; Pinched flow fractionation

Indexed keywords

CELLS; CYTOLOGY; HYDRODYNAMICS; MICROFLUIDICS; SCREENING;

CELL SORTING; DISSIPATIVE PARTICLE DYNAMICS; DISSIPATIVE PARTICLE DYNAMICS METHOD (DPD); DPD SIMULATIONS; EXTENDED OBJECTS; HYDRODYNAMIC FORCES; MICRO TOTAL ANALYSIS SYSTEMS; PINCHED-FLOW FRACTIONATIONS;

BLOOD;

EID: 84878534737     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-012-1073-9     Document Type: Article

References (42)

1. Abkarian M, Viallat A (2008) Vesicles and red blood cells in shear flow. Soft Matter 4:653-657
2. Boryczko K, Dzwinel W, Yuen DA (2003a) Dynamical clustering of red blood cells in capillary vessels. J Mol Mod 9(1):16-33
3. Boryczko K, Dzwinel W, Yuen DA (2003b) Clustering revealed in high-resolution simulations and visualization of multi-resolution features in fluid-particle models. Concurr Comput Pract Exp 15(2):101-116
4. Boryczko K, Dzwinel W, Yuen DA (2004) Modeling fibrin aggregation in blood flow with discrete-particles. Comput Method Prog Bio 75(3):181-194
5. Brenner T (2005) Polymer fabrication and microfluidic unit operations for medical diagnostics on a rotating disk. Thesis/dissertation. http://urn:nbn:de:bsz:25-opus-23062, http://www.freidok.uni-freiburg.de/ volltexte/2306
6. Cherukat P, McLaughlin JB (1994) The inertial lift on a rigid sphere in a linear shear flow field near a flat wall. J Fluid Mech 263:1-18
7. Cherukat P, McLaughlin JB, Dandy DS (1999) A computational study of the inertial lift on a sphere in a linear shear flow field. Int J Multiphase Flow 25:15-33
8. Cox RG, Hsu SK (1977) The lateral migration of solid particles in a laminar flow near a plane. Int J Multiphase Flow 3:201-222
9. Cupelli C, Henrich B, Glatzel T, Moseler M, Zengerle R, Santer M (2008) Dynamic capillary wetting studied with dissipative particle dynamics. New J Phys 10(4):043009
10. Di Carlo D, Irimia D, Tompkins RG, Toner M (2007) Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci USA 104(48):18892-18897
11. El-Kareh AW, Secomb TW (2000) A model for red blood cell motion in bifurcating microvessels. Int J Multiphase Flow 26:1545-1564
12. Español P, Warren PB (1995) Statistical-mechanics of dissipative particle dynamics. Europhys Lett 30(4):191-196
13. Fedosov DA, Caswell B, Karniadakis GE (2010a) Systematic coarse-graining of spectrin-level red blood cell models. Comput Method Appl Mech Eng 199:1937-1948
14. Fedosov DA, Caswell B, Karniadakis GE (2010b) A multiscale red blood cell model with accurate mechanics, rheology and dynamics. Biophys J 98:2215-2225
15. Groot RD, Warren PB (1997) Dissipative particle dynamics: bridging the gap between atomistic and mesoscopic simulation. J Chem Phys 107(11):4423-4435
16. Henrich B, Cupelli C, Moseler M, Zengerle R, Santer M (2007) An adhesive DPD wall model for dynamic wetting. Europhys Lett 80(6):60004
17. Howard M (2003) Shapiro practical flow cytometry, 4th edn. Wiley, New York (Published online 28 Jan 2005)
18. Liu Y, Liu WK (2006) Rheology of red blood cell aggregation by computer simulation. J Comput Phys 220(1):139-154
19. Lowe CP (1999) An alternative approach to dissipative particle dynamics. Europhys Lett 47(2):145-151
20. Marsh CA, Backx G, Ernst MH (1997) Static and dynamic properties of dissipative particle dynamics. Phys Rev E 56(2):1676-1691
21. Noguchi H, Gompper G (2005) Shape transitions of fluid vesicles and red blood cells in capillary flows. Proc Natl Acad Sci USA 102(40):14159-14164
22. Olla P (1999) Simplified model for red cell dynamics in small blood vessels. Phys Rev Lett 6(5):453-456
23. Peters EAJF (2004) Elimination of time step effects in DPD. Europhys Lett 66(3):311-317
24. Pozrikidis C (2003) Numerical simulation of the flow-induced deformation of red blood cells. Ann Biomed Eng 31:1194-1205
25. Riegger L et al (2006) Read-out concepts for multiplexed bead-based fluorescence immunoassays on centrifugal microfluidic platforms. Sens Actuators A 126:455-462
26. Roberts BW, Olbricht WL (2003) Flow-induced particulate separations. AIChE J 49(11):2842-2849
27. Roberts BW, Olbricht WL (2006) The distribution of freely suspended particles at microfluidic bifurcations. AIChE J 52(1):199-206
28. Rubinow SI, Keller JB (1999) The transverse force on a spinning sphere moving in a viscous fluid. J Fluid Mech 11:447-459
29. Saffman PG (1965) The lift on a small sphere in a slow shear flow. J Fluid Mech 22(2):385-400
30. Segré G, Silberberg A (1961) Radial particle displacements in Poisseuille flow of suspensions. Nature 189:209-210
31. Steiner T, Cupelli C, Zengerle R, Santer M (2009) Simulation of advanced microfluidic systems with dissipative particle dynamics. Microfluid Nanofluid 7:307-323
32. Sun C, Migliori C, Munn LL (2003) Red blood cells initiate leukocyte rolling in postcapillary expansions: a lattice boltzmann analysis. Biophys J 85:208-222
33. Takagi J, Yamada M, Yasuda M, Seki M (2005) Continuous particle separation in a microchannel having asymmetrically arranged multiple branches. Lab Chip 5(7):778-784
34. Takemura F, Magnaudet J (2003) The transverse force on clean and contaminated bubbles rising near a vertical wall at moderate Reynolds number. J Fluid Mech 495:235-253
35. Tokarev A, Panasenko G, Ataullakhanov F (2011) Segregation of flowing blood: mathematical description. Math Model Nat Phenom 6(5):281-319
36. Young B, Lowe JS, Stevens A, Heart JW (2006) Wheater's functional histology, 5th edn. Churchill Livingstone, London
37. Worth Longest P, Kleinstreuer C, Buchanan JR (2004) Efficient computation of micro-particle dynamics including wall effects. Comput Fluids 33:577-601
38. Vattulainen I, Karttunen M, Besold G, Polson JM (2002) Integration schemes for dissipative particle dynamics simulations: from softly interacting systems towards hybrid models. J Chem Phys 116(10):3967-3979
39. Yamada M, Nakashima M, Seki M (2004) Pinched flow fractionation: continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel. Anal Chem 76(18):5465-5471
40. Yamada M, Seki M (2005) Hydrodynamic filtration for on-chip particle concentration and classification utilizing microfluidics. Lab Chip 5(11):1233-1239
41. Yamada M, Seki M (2006) Microfluidic particle sorter employing flow splitting and recombining. Anal Chem 78(4):1357-1362
42. Zeng L, Balachandar S, Fischer P (2005) Wall-induced forces on a rigid sphere at finite Reynolds number. J Fluid Mech 536:1-25