An agent based model of integrin clustering: Exploring the role of ligand clustering, integrin homo-oligomerization, integrin-ligand affinity, membrane crowdedness and ligand mobility

Journal of Computational Physics

Volumn 244, Issue , 2013, Pages 264-278

  Jamali, Yousef ^a   Jamali, Tahereh ^a   Mofrad, Mohammad R K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Agent based modeling; Cellular mechanotransduction; Computational physics; Focal adhesions; Integrin; Integrin clustering; Multiscale

Indexed keywords

ADHESION; AUTONOMOUS AGENTS; CELL MEMBRANES; COMPUTATIONAL METHODS; GLYCOPROTEINS; LIGANDS; OLIGOMERS; SIGNAL TRANSDUCTION;

AGENT-BASED MODEL; CELLULAR MECHANOTRANSDUCTION; CELLULARS; CLUSTERINGS; COMPUTATIONAL PHYSICS; FOCAL ADHESIONS; INTEGRIN CLUSTERING; INTEGRINS; MECHANOTRANSDUCTION; MULTISCALE;

OLIGOMERIZATION;

EID: 84878507582     PISSN: 00219991     EISSN: 10902716     Source Type: Journal    
DOI: 10.1016/j.jcp.2012.09.010     Document Type: Article

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