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Volumn 100, Issue 3, 2013, Pages 289-297

Is the Hp 2-2 diabetic mouse model a good model to study diabetic nephropathy?

Author keywords

Diabetic nephropathy; Haptoglobin; Mice model; Streptozotocin; Type 1 DM

Indexed keywords

ALBUMIN; COLLAGEN TYPE 4; HAPTOGLOBIN; IRON; LIPID PEROXIDE; SMOOTH MUSCLE ACTIN;

EID: 84878482764     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2013.02.004     Document Type: Review
Times cited : (6)

References (31)
  • 1
    • 0035856920 scopus 로고    scopus 로고
    • Global and social implications of the diabetes epidemic
    • Zimmet P., Alberti K.G., Shaw J. Global and social implications of the diabetes epidemic. Nature 2001, 414:782-787.
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 5
    • 84860425021 scopus 로고    scopus 로고
    • Haptoglobin genotype and its role in determining heme-iron mediated vascular disease
    • July (1)
    • Goldenstein H., Levy N.S., Levy A.P. Haptoglobin genotype and its role in determining heme-iron mediated vascular disease. Pharmacol Res 2012, 66(July (1)):1-6.
    • (2012) Pharmacol Res , vol.66 , pp. 1-6
    • Goldenstein, H.1    Levy, N.S.2    Levy, A.P.3
  • 6
    • 84866098563 scopus 로고    scopus 로고
    • Haptoglobin genotype and its role in diabetic cardiovascular disease
    • August (4)
    • Costacou T., Levy A.P. Haptoglobin genotype and its role in diabetic cardiovascular disease. J Cardiovasc Transl Res 2012, 5(August (4)):423-435.
    • (2012) J Cardiovasc Transl Res , vol.5 , pp. 423-435
    • Costacou, T.1    Levy, A.P.2
  • 7
    • 77049116995 scopus 로고    scopus 로고
    • The haptoglobin 2-2 genotype is associated with increased redox active hemoglobin derived iron in the atherosclerotic plaque
    • March (1)
    • Kalet-Litman S., Moreno P.R., Levy A.P. The haptoglobin 2-2 genotype is associated with increased redox active hemoglobin derived iron in the atherosclerotic plaque. Atherosclerosis 2010, 209(March (1)):28-31.
    • (2010) Atherosclerosis , vol.209 , pp. 28-31
    • Kalet-Litman, S.1    Moreno, P.R.2    Levy, A.P.3
  • 8
    • 77956239512 scopus 로고    scopus 로고
    • Diabetic nephropathy-challenges in pathologic classification
    • September
    • Fioretto P., Mauer M. Diabetic nephropathy-challenges in pathologic classification. Nat Rev Nephrol 2010, 6(September):508-510.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 508-510
    • Fioretto, P.1    Mauer, M.2
  • 11
    • 84856601382 scopus 로고    scopus 로고
    • A novel diabetes mellitus mouse model, MAFK-overexpressing hybride transgenic mice, developed severe diabetic nephropathy and improved with TCV-111 (Candesartan Cilexetil) treatment
    • Fujita A., Yoh K., Shimohata H., Morito N., Ojima M., Yahagata K. A novel diabetes mellitus mouse model, MAFK-overexpressing hybride transgenic mice, developed severe diabetic nephropathy and improved with TCV-111 (Candesartan Cilexetil) treatment. Exp Anim 2012, 61(1):49-57.
    • (2012) Exp Anim , vol.61 , Issue.1 , pp. 49-57
    • Fujita, A.1    Yoh, K.2    Shimohata, H.3    Morito, N.4    Ojima, M.5    Yahagata, K.6
  • 12
    • 84859348722 scopus 로고    scopus 로고
    • Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion
    • April (4)
    • Chang J.H., Paik S.Y., Mao L., Eisner W., Flannery P.J., Wang L., et al. Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion. PLoS ONE 2012, 7(April (4)):4.
    • (2012) PLoS ONE , vol.7 , pp. 4
    • Chang, J.H.1    Paik, S.Y.2    Mao, L.3    Eisner, W.4    Flannery, P.J.5    Wang, L.6
  • 13
    • 50149083681 scopus 로고    scopus 로고
    • Pharmacogenomic application of the haptoglobin genotype in the prevention of diabetic cardiovascular disease
    • August (8)
    • Blum S., Milman U., Shapira C., Levy A.P. Pharmacogenomic application of the haptoglobin genotype in the prevention of diabetic cardiovascular disease. Pharmacogenomics 2008, 9(August (8)):989-991.
    • (2008) Pharmacogenomics , vol.9 , pp. 989-991
    • Blum, S.1    Milman, U.2    Shapira, C.3    Levy, A.P.4
  • 14
    • 33947497535 scopus 로고    scopus 로고
    • In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease
    • Asleh R., Levy A.P. In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease. Vasc Health Risk Manag 2005, 1(1):19-28.
    • (2005) Vasc Health Risk Manag , vol.1 , Issue.1 , pp. 19-28
    • Asleh, R.1    Levy, A.P.2
  • 15
    • 65949087452 scopus 로고    scopus 로고
    • Pharmacogenomic effect of vitamin E on kidney structure and function in transgenic mice with the haptoglobin 2-2 genotype and diabetes mellitus
    • [Epub 2009 Jan 28], April (4)
    • Nakhoul F.M., Miller-Lotan R., Awad H., Asleh R., Jad K., Nakhoul N., et al. Pharmacogenomic effect of vitamin E on kidney structure and function in transgenic mice with the haptoglobin 2-2 genotype and diabetes mellitus. Am J Physiol Renal Physiol 2009, 296(April (4)):F830-F838. [Epub 2009 Jan 28].
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Nakhoul, F.M.1    Miller-Lotan, R.2    Awad, H.3    Asleh, R.4    Jad, K.5    Nakhoul, N.6
  • 16
  • 17
    • 84864416943 scopus 로고    scopus 로고
    • Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus
    • Asleh R., Nakhoul F.M., Miller-Lotan R., Awad H., Farbstein D., Levy N.S., et al. Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus. Free Radic Biol Med 2012, 53(4):779-786.
    • (2012) Free Radic Biol Med , vol.53 , Issue.4 , pp. 779-786
    • Asleh, R.1    Nakhoul, F.M.2    Miller-Lotan, R.3    Awad, H.4    Farbstein, D.5    Levy, N.S.6
  • 18
    • 33847217986 scopus 로고    scopus 로고
    • Retinal capillary basement membrane thickness in diabetic mice genetically modified at the haptoglobin locus
    • Miller-Lotan R., Miller B., Nakhoul F., Aronson D., Asaf R., Levy A.P. Retinal capillary basement membrane thickness in diabetic mice genetically modified at the haptoglobin locus. Diabetes Metab Res Rev 2007 Feb, 23(2):152-156.
    • (2007) Diabetes Metab Res Rev , vol.23 , Issue.2 , pp. 152-156
    • Miller-Lotan, R.1    Miller, B.2    Nakhoul, F.3    Aronson, D.4    Asaf, R.5    Levy, A.P.6
  • 20
    • 53149150561 scopus 로고    scopus 로고
    • Regulation of CD163 associated casein kinase II activity is haptoglobin genotype dependent
    • October (1-2)
    • Strauss M., Levy A.P. Regulation of CD163 associated casein kinase II activity is haptoglobin genotype dependent. Mol Cell Biochem 2008, 317(October (1-2)):131-135.
    • (2008) Mol Cell Biochem , vol.317 , pp. 131-135
    • Strauss, M.1    Levy, A.P.2
  • 22
    • 0037378785 scopus 로고    scopus 로고
    • Atubular glomeruli and glomerulotubular junction abnormalities in diabetic nephropathy
    • Behzad N., Kim Y., John T., Crosson T., Mauer M. Atubular glomeruli and glomerulotubular junction abnormalities in diabetic nephropathy. J Am Soc Nephrol 2003, 14:908-917.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 908-917
    • Behzad, N.1    Kim, Y.2    John, T.3    Crosson, T.4    Mauer, M.5
  • 23
    • 84865680790 scopus 로고    scopus 로고
    • Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature
    • October (7)
    • Vardi M., Blum S., Levy A.P. Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature. Eur J Intern Med 2012, 23(October (7)):628-632.
    • (2012) Eur J Intern Med , vol.23 , pp. 628-632
    • Vardi, M.1    Blum, S.2    Levy, A.P.3
  • 24
    • 77954314742 scopus 로고    scopus 로고
    • The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes
    • July (1)
    • Blum S., Vardi M., Levy N.S., Miller-Lotan R., Levy A.P. The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes. Atherosclerosis 2010, 211(July (1)):25-27.
    • (2010) Atherosclerosis , vol.211 , pp. 25-27
    • Blum, S.1    Vardi, M.2    Levy, N.S.3    Miller-Lotan, R.4    Levy, A.P.5
  • 25
    • 0027988510 scopus 로고
    • Lysosomal iron accumulation in diabetic nephropathy
    • Nankivell B.J., Tay Y.C., Boadle R.A., Harris D.C. Lysosomal iron accumulation in diabetic nephropathy. Ren Fail 1994, 16:367-381.
    • (1994) Ren Fail , vol.16 , pp. 367-381
    • Nankivell, B.J.1    Tay, Y.C.2    Boadle, R.A.3    Harris, D.C.4
  • 26
    • 84863445098 scopus 로고    scopus 로고
    • Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis
    • July (2)
    • Purushothaman K.R., Purushothaman M., Levy A.P., Lento P.A., Evrard S., Kovacic J.C., et al. Increased expression of oxidation-specific epitopes and apoptosis are associated with haptoglobin genotype: possible implications for plaque progression in human atherosclerosis. J Am Coll Cardiol 2012, 60(July (2)):112-119.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 112-119
    • Purushothaman, K.R.1    Purushothaman, M.2    Levy, A.P.3    Lento, P.A.4    Evrard, S.5    Kovacic, J.C.6
  • 27
    • 81255172201 scopus 로고    scopus 로고
    • Haptoglobin genotype predicts development of coronary artery calcification in a prospective cohort of patients with type 1 diabetes
    • Simpson M., Snell-Bergeon J.K., Kinney G.L., Lache O., Miller-Lotan R., Anbinder Y., et al. Haptoglobin genotype predicts development of coronary artery calcification in a prospective cohort of patients with type 1 diabetes. Cardiovasc Diabetol 2011, 10:99.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 99
    • Simpson, M.1    Snell-Bergeon, J.K.2    Kinney, G.L.3    Lache, O.4    Miller-Lotan, R.5    Anbinder, Y.6
  • 28
    • 51449122325 scopus 로고    scopus 로고
    • Haptoglobin genotype is a major determinant of the amount of iron in the human atherosclerotic plaque
    • September (13)
    • Moreno P.R., Purushothaman K.R., Purushothaman M., Muntner P., Levy N.S., Fuster V., et al. Haptoglobin genotype is a major determinant of the amount of iron in the human atherosclerotic plaque. J Am Coll Cardiol 2008, 52(September (13)):1049-1051.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1049-1051
    • Moreno, P.R.1    Purushothaman, K.R.2    Purushothaman, M.3    Muntner, P.4    Levy, N.S.5    Fuster, V.6
  • 29
    • 84870501767 scopus 로고    scopus 로고
    • Vitamin D receptor signaling in podocytes protects against diabetic nephropathy
    • Wang Y., Deb D.K., Zhang Z., Sun T., Liu W., Yoon D., et al. Vitamin D receptor signaling in podocytes protects against diabetic nephropathy. J Am Soc Nephrol 2012, 23:1977-1986.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1977-1986
    • Wang, Y.1    Deb, D.K.2    Zhang, Z.3    Sun, T.4    Liu, W.5    Yoon, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.