Optimal testing of the live organ donor for blood-borne viral pathogens: The report of a consensus conference

American Journal of Transplantation

Volumn 13, Issue 6, 2013, Pages 1405-1415

  Blumberg, E A ^a   Ison, M G ^b   Pruett, T L ^c   Segev, D L ^d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Donor infection; hepatitis B virus; hepatitis C virus; HIV; live donor transplantation; testing

Indexed keywords

COCAINE DEPENDENCE; CONFERENCE PAPER; CONSENSUS DEVELOPMENT; DONOR SELECTION; ENDEMIC DISEASE; ENZYME IMMUNOASSAY; GENITAL ULCER; HEMOPHILIA; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HEROIN DEPENDENCE; HIGH RISK POPULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; INFORMED CONSENT; INTRAVENOUS DRUG ABUSE; LABORATORY TEST; LIVING DONOR; MALE HOMOSEXUAL; NONHUMAN; NUCLEIC ACID ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PRISONER; PROSTITUTION; PUBLIC HEALTH SERVICE; RISK ASSESSMENT; SEXUALLY TRANSMITTED DISEASE; TRAVEL; UNITED STATES; VIRUS DETECTION; VIRUS INFECTION; VIRUS PATHOGENESIS; VIRUS TRANSMISSION;

BLOOD-BORNE PATHOGENS; CONSENSUS DEVELOPMENT CONFERENCES AS TOPIC; DNA, VIRAL; HUMANS; LIVING DONORS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; VIRUS DISEASES; VIRUSES;

EID: 84878472440     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12205     Document Type: Conference Paper

References (34)

1. HIV transmitted from a living organ donor-New York City. 2009; MMWR Morbidity and mortality weekly report 2011; 60: 297-301.
2. Pittsburgh Post Gazette 2011.
3. Landro L., Organ recipient gets HIV. Wall St J 2011. Available at: http://online.wsj.com/article/SB10001424052748704261504576205050495573230.html. Accessed April 4, 2013.
4. Segev DL, Gentry SE, Warren DS, Reeb B, Montgomery RA., Kidney paired donation and optimizing the use of live donor organs. JAMA 2005; 293: 1883-1890.
5. Humar A, Morris M, Blumberg E, et al. Nucleic acid testing (NAT) of organ donors: Is the 'best' test the right test? A consensus conference report. Am J Transplant 2010; 10: 889-899.
6. Guidelines for preventing transmission of human immunodeficiency virus through transplantation of human tissue and organs. Centers for disease control and prevention. MMWR Recomm Rep 1994; 43: 1-17.
7. Kucirka LM, Sarathy H, Govindan P, et al. Risk of window period hepatitis-C infection in high infectious risk donors: Systematic review and meta-analysis. Am J Transplant 2011; 11: 1188-1200.
8. Kucirka LM, Sarathy H, Govindan P, et al. Risk of window period HIV infection in high infectious risk donors: Systematic review and meta-analysis. Am J Transplant 2011; 11: 1176-1187.
9. Stramer SL, Wend U, Candotti D, et al. Nucleic acid testing to detect HBV infection in blood donors. N Engl J Med 2011; 364: 236-247.
10. Venettoni S, Emilio SC, Scalamogna M, et al. Strategies for evaluation of suitable donors: Italian experience. Ann Transplant 2004; 9: 15-16.
11. OPTN. Guidance for the Medical Evaluation of Potential Living Liver Donors.
12. Association JWPoTBTSaTR. United Kingdom Guidelines For Living Donor Kidney Transplantation. 2011.
13. Council AGNHaMR. Organ and Tissue Donation by Living Donors Guidelines for Ethical Practice for Health Professionals. 2007.
14. OPTN. Guidance for the Development of Program-Specific Living Kidney Donor Medical Evaluation Protocols.
15. Guidelines for Laboratory Testing and Result Reporting of Antibody to Hepatitis C Virus. MMWR 2003; 52: 1-16.
16. Revised Recommendations for HIV Testing of Adults, Adolescents and Pregnant Women in Health-Care Settings. MMWR 2006; 55: 1-17.
17. Recommendations for Identification and Public Health Management of Persons with Chronic Hepatitis B Virus Infection. MMWR 2008; 57: 1-20.
18. Recommendations for prevention and control of hepatitis C virus [HCV] infection and HCV-related chronic disease. MMWR 1998; 47: 1-33.
19. Z900.2. 3-03. Perfusable Organs for Transplantation. (Accessed July 11, 2012, at http://shop.csa.ca/en/canada/transplantation/cancsa-z90023-03-r2008/ invt/27017652003/&bklist=icat,5,shop,publications,healthcare, transplantation.)
20. Gordon EJ, Beauvais N, Theodoropoulos N, et al. The challenge of informed consent for increased risk living donation and transplantation. Am J Transplant 2011; 11: 2569-2574.
21. Abecassis M, Adams M, Adams P, et al. Consensus statement on the live organ donor. JAMA 2000; 284: 2919-2926.
22. North American Transplant Coordinators Organization Public Policy statement. Living donor transplantation. Prog Transplant 2002; 12: 314-315.
23. The consensus statement of the Amsterdam Forum on the care of the live kidney donor. Transplantation 2004; 78: 491-492.
24. Rodrigue JR, Pavlakis M, Danovitch GM, et al. Evaluating living kidney donors: Relationship types, psychosocial criteria and consent processes at US transplant programs. Am J Transplant 2007; 7: 2326-2332.
25. Pruett TL, Tibell A, Alabdulkareem A, et al. The ethics statement of the Vancouver forum on the live lung, liver, pancreas and intestine donor. Transplantation 2006; 81: 1386-1387.
26. (Accessed at http://optn.transplant.hrsa.gov/ContentDocuments/Guidance- InformedConsentLiving-Donors.pdf.)
27. Kucirka LM, Namuyinga R, Hanrahan C, Montgomery RA, Segev DL., Formal policies and special informed consent are associated with higher provider utilization of CDC high-risk donor organs. Am J Transplant 2009; 9: 629-635.
28. Hizo-Abes P, Young A, Reese PP, et al. Attitudes to sharing personal health information in living kidney donation. Clin J Am Soc Nephrol 2010; 5: 717-722.
29. Segev DL, Kucirka LM, Gentry SE, Montgomery RA., Utilization and outcomes of kidney paired donation in the United States. Transplantation 2008; 86: 502-510.
30. (Accessed July 11, 2012, at http://aids.gov/hiv-aids-basics/just- diagnosed-with-hiv-aids/your-legal-rights/legal-disclosure/.)
31. Freeman RB, Cohen JT., Transplantation risks and the real world: What does 'high risk' really mean ? Am J Transplant 2009; 9: 23-30.
32. Guidance for the informed consent of living donors. (Accessed at http://optn.transplant.hrsa.gov/ContentDocuments/Guidance-InformedConsentLiving- Donors.pdf.)
33. Transplantation) AACoO. U.S. Department of Health and Human Services Recommendations 1-18.
34. Minimum procurement standards for an organ procurement organization. (Accessed July 7, 2012, at http://optn.transplant.hrsa.gov/PoliciesandBylaws2/ policies/pdfs/policy-2.pdf.)