메뉴 건너뛰기




Volumn 56, Issue 5, 2013, Pages 191-195

Phenotypes and endotypes of severe asthma in children

Author keywords

Child; Endotype; Phenotype; Severe asthma

Indexed keywords

CORTICOSTEROID; CXCL1 CHEMOKINE; GAMMA INTERFERON; GLUCOCORTICOID; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 8; METHACHOLINE; MONOCLONAL ANTIBODY;

EID: 84878465431     PISSN: 17381061     EISSN: 20927258     Source Type: Journal    
DOI: 10.3345/kjp.2013.56.5.191     Document Type: Review
Times cited : (6)

References (32)
  • 2
    • 33845987340 scopus 로고    scopus 로고
    • Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 2007; 119:405-13.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 405-413
    • Moore, W.C.1    Bleecker, E.R.2    Curran-Everett, D.3    Erzurum, S.C.4    Ameredes, B.T.5    Bacharier, L.6
  • 8
    • 79551500941 scopus 로고    scopus 로고
    • Heterogeneity of severe asthma in childhood: Confirmation by cluster analysis of children in the National Institutes of Health/ National Heart, Lung, and Blood Institute Severe Asthma Research Program
    • 382-9+e1-13
    • Fitzpatrick AM, Teague WG, Meyers DA, Peters SP, Li X, Li H, et al. Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/ National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol 2011;127:382-9. e1-13.
    • (2011) J Allergy Clin Immunol , vol.127
    • Fitzpatrick, A.M.1    Teague, W.G.2    Meyers, D.A.3    Peters, S.P.4    Li, X.5    Li, H.6
  • 11
    • 67049108516 scopus 로고    scopus 로고
    • Pediatric asthma: A different disease
    • Gelfand EW. Pediatric asthma: a different disease. Proc Am Thorac Soc 2009;6:278-82.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 278-282
    • Gelfand, E.W.1
  • 12
    • 33845191620 scopus 로고    scopus 로고
    • Features of severe asthma in school-age children: Atopy and increased exhaled nitric oxide
    • National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program
    • Fitzpatrick AM, Gaston BM, Erzurum SC, Teague WG; National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. Features of severe asthma in school-age children: atopy and increased exhaled nitric oxide. J Allergy Clin Immunol 2006;118:1218-25.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 1218-1225
    • Fitzpatrick, A.M.1    Gaston, B.M.2    Erzurum, S.C.3    Teague, W.G.4
  • 14
    • 0025004551 scopus 로고
    • Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood: A prospective study
    • Sporik R, Holgate ST, Platts-Mills TA, Cogswell JJ. Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood: a prospective study. N Engl J Med 1990;323:502-7.
    • (1990) N Engl J Med , vol.323 , pp. 502-507
    • Sporik, R.1    Holgate, S.T.2    Platts-Mills, T.A.3    Cogswell, J.J.4
  • 16
    • 78649261484 scopus 로고    scopus 로고
    • Severe asthma in children: Insights from the National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Fitzpatrick AM, Teague WG. Severe asthma in children: insights from the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Pediatr Allergy Immunol Pulmonol 2010;23:131-8.
    • (2010) Pediatr Allergy Immunol Pulmonol , vol.23 , pp. 131-138
    • Fitzpatrick, A.M.1    Teague, W.G.2
  • 17
  • 18
    • 77950215411 scopus 로고    scopus 로고
    • The molecular phenotype of severe asthma in children
    • National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program
    • Fitzpatrick AM, Higgins M, Holguin F, Brown LA, Teague WG; National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. The molecular phenotype of severe asthma in children. J Allergy Clin Immunol 2010;125:851-7. e18.
    • (2010) J Allergy Clin Immunol , vol.125
    • Fitzpatrick, A.M.1    Higgins, M.2    Holguin, F.3    Brown, L.A.4    Teague, W.G.5
  • 20
    • 0030859389 scopus 로고    scopus 로고
    • Bronchoscopic evaluation of severe asthma; persistent inflammation associated with high dose glucocorticoids
    • Wenzel SE, Szefler SJ, Leung DY, Sloan SI, Rex MD, Martin RJ. Bronchoscopic evaluation of severe asthma; persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med 1997;156(3 Pt 1):737-43.
    • (1997) Am J Respir Crit Care Med , vol.156 , Issue.3 PART 1 , pp. 737-743
    • Wenzel, S.E.1    Szefler, S.J.2    Leung, D.Y.3    Sloan, S.I.4    Rex, M.D.5    Martin, R.J.6
  • 22
    • 84863393701 scopus 로고    scopus 로고
    • Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines
    • Bossley CJ, Fleming L, Gupta A, Regamey N, Frith J, Oates T, et al. Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines. J Allergy Clin Immunol 2012;129:974-82. e13.
    • (2012) J Allergy Clin Immunol , vol.129
    • Bossley, C.J.1    Fleming, L.2    Gupta, A.3    Regamey, N.4    Frith, J.5    Oates, T.6
  • 24
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: New insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • Anderson GP. Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 2008;372:1107-19.
    • (2008) Lancet , vol.372 , pp. 1107-1119
    • Anderson, G.P.1
  • 25
    • 84856845581 scopus 로고    scopus 로고
    • Severe asthma: From characteristics to phenotypes to endotypes
    • Wenzel S. Severe asthma: from characteristics to phenotypes to endotypes. Clin Exp Allergy 2012;42:650-8.
    • (2012) Clin Exp Allergy , vol.42 , pp. 650-658
    • Wenzel, S.1
  • 28
    • 0142010551 scopus 로고    scopus 로고
    • A comparison of the clinical characteristics of children and adults with severe asthma
    • Jenkins HA, Cherniack R, Szefler SJ, Covar R, Gelfand EW, Spahn JD. A comparison of the clinical characteristics of children and adults with severe asthma. Chest 2003;124:1318-24.
    • (2003) Chest , vol.124 , pp. 1318-1324
    • Jenkins, H.A.1    Cherniack, R.2    Szefler, S.J.3    Covar, R.4    Gelfand, E.W.5    Spahn, J.D.6
  • 29
    • 78650921930 scopus 로고    scopus 로고
    • Progressive airflow limitation is a feature of children with severe asthma
    • National Institutes of Health/National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Fitzpatrick AM, Teague WG; National Institutes of Health/National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Progressive airflow limitation is a feature of children with severe asthma. J Allergy Clin Immunol 2011;127:282-4.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 282-284
    • Fitzpatrick, A.M.1    Teague, W.G.2
  • 30
    • 79953670552 scopus 로고    scopus 로고
    • Sex dependence of airflow limitation and air trapping in children with severe asthma
    • National Institutes of Health, National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Sorkness RL, Teague WG, Penugonda M, Fitzpatrick AM; National Institutes of Health, National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Sex dependence of airflow limitation and air trapping in children with severe asthma. J Allergy Clin Immunol 2011;127:1073-4.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1073-1074
    • Sorkness, R.L.1    Teague, W.G.2    Penugonda, M.3    Fitzpatrick, A.M.4
  • 31
    • 77955896917 scopus 로고    scopus 로고
    • Long-term studies of the natural history of asthma in childhood
    • Bisgaard H, Bonnelykke K. Long-term studies of the natural history of asthma in childhood. J Allergy Clin Immunol 2010;126:187-97.
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 187-197
    • Bisgaard, H.1    Bonnelykke, K.2
  • 32
    • 33745114978 scopus 로고    scopus 로고
    • Gender differences in IgE-mediated allergic asthma in the epidemiology and natural history of asthma: Outcomes and Treatment Regimens (TENOR) study
    • Tenor Study Group
    • Lee JH, Haselkorn T, Chipps BE, Miller DP, Wenzel SE; Tenor Study Group. Gender differences in IgE-mediated allergic asthma in the epidemiology and natural history of asthma: Outcomes and Treatment Regimens (TENOR) study. J Asthma 2006;43:179-84.
    • (2006) J Asthma , vol.43 , pp. 179-184
    • Lee, J.H.1    Haselkorn, T.2    Chipps, B.E.3    Miller, D.P.4    Wenzel, S.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.