Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 32, Issue 1, 2013, Pages 41-51

  Hou, Lichao ^a,b   Bowman, Linda ^b   Meighan, Terence G ^b   Shi, Xianglin ^a   Ding, Min ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Cell signal pathways; JB6 cells; microRNA 21; Nanoparticles; Nanotoxicology; Occupational exposure; Occupational respiratory disease; Oncogenicity; PDCD4; Tungsten carbide cobalt

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; CATALASE; COBALT; HYDROGEN PEROXIDE; METAL NANOPARTICLE; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE P38; PROGRAMMED CELL DEATH 4; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN; TUNGSTEN CARBIDE; TUNGSTEN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; ENZYME INHIBITION; EPIDERMIS CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SURFACE PROPERTY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BUTADIENES; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; COBALT; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; EPIDERMIS; HYDROGEN PEROXIDE; IMIDAZOLES; MAP KINASE SIGNALING SYSTEM; MICE; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NANOPARTICLES; NITRILES; OCCUPATIONAL EXPOSURE; PYRIDINES; REACTIVE OXYGEN SPECIES; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TUNGSTEN COMPOUNDS;

EID: 84878464402     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: 10.1615/JEnvironPatholToxicolOncol.2013007097     Document Type: Article

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