Synthesis and hypoglycemic activity of esterified-derivatives of mangiferin

Chinese Journal of Natural Medicines

Volumn 11, Issue 3, 2013, Pages 296-301

  Li, Xue Jian ^a,b   Du, Zheng Cai ^b   Huang, Yan ^c   Liu, Bu Ming ^c   Hu, Wen Ji ^b   Lu, Wen Jie ^c   Deng, Jia Gang ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b GUANGXI UNIVERSITY OF CHINESE MEDICINE   (China)

^c Guangxi Institute of Traditional Medical & Pharmaceutical Sciences   (China)

Author keywords

Hypoglycemic activity; Mangiferin derivatives; Synthesis

Indexed keywords

3,6,7,2',3',4' HEPTA PROPIONYL MANGIFERIN; 3,6,7,2',3',4' HEXA BUTYRYL MANGIFERIN; 7,2',3',4',6' PENTA ACETYL MANGIFERIN; ANTIDIABETIC AGENT; MANGIFERIN; METFORMIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HISTOLOGY; HYPERGLYCEMIA; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84878440631     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(13)60032-1     Document Type: Article

References (14)

1. Ren XG, Li WD, He CM, et al. Advanced research on the pharmacology of mangiferin [J]. Chin Tradit Pat Med 2011, 33(5):860-863.
2. Kant Singh S, Sinha SK, Prasad S, et al. Synthesis and evaluation of novel analogues of mangiferin as potent antipyretic [J]. Asian Pac J Trop Med 2011, 4(11):866-869.
3. Liao HL, Wu QY, Hu HG, et al. Structure modification of mangiferin [J]. West China J Pharm Sci 2008, 23(4):385-387.
4. Liao HL, Chen J, Yang Q Preparation of mangiferin derivatives [J]. Chem Bioeng 2011, 27(5):49-50.
5. Zhou Y, Hu LN, Luo JF, et al. Synthesis and PTP1B activity of enzyme inhibition of mangiferin derivates [J]. J Pharm Prac 2011, 29(3):193-196.
6. Cantagrel N, Lubrano C, Robin JR. Glycosylation of mangiferin by biocatalyst useful in cosmetic field to protect skin comprises contacting mangiferin with a glycosyltransferase enzyme, in the presence of a sugar donor: FR, 2882762 (A1) [P]. 2006-09-08.
7. Li XJ, Deng JG, Qin ZL, et al. Experimental study on hypoglycemic effect of the mixture of mangiferin and berberine [J]. Mod Chin Med 2008, 10(12):26-28.
8. Liederer BM, Borchardt RT Enzymes involved in the bioconversion of ester-based prodrugs [J]. J Pharm Sci 2006, 95:1177-1195.
9. Hu YJ, Liu S, Wang DY Chemical constituents of the leaf of Mangifera indica [J]. Asia-Pac Tradit Med 2010, 6(2):18-19.
10. Wei S, Yang XL, Zhao WF, et al. Chemical constituents of Mangifera persiciform [J]. Chin Tradit Pat Med 2008, 30(9):1399-1400.
11. Yuan GJ, Yi YK Studies on chemical constituents of the roots of Salacia hainanensis [J]. J Chin Med Mat 2005, 28(1):27-29.
12. Rancona S, Chaboud A, Darbour N, et al. A new C-glycosyl xanthone isolated from Dayallia solida [J]. Phytochemistry 1999, 52:1677-1679.
13. Li ZH Synthesis Principle of Organic Drugs [M] 1985, 636-642. People's Health Publishing House, Beijing. 1st ed.
14. Yu DK, Yang W, Zhang MX, et al. Anti-diabetic effects of extractives of marine algae in streptozotocin-induced diabetic rats [J]. West China J Pharm Sci 2009, 24(1):32-34.